SST5 receptor homology model

PROTEIN CLASS

Class A (Rhodopsin)

RECEPTOR

SPECIES

Homo sapiens

STATE

Active

VERSION

2021-09-08

MODEL

PDB file contains GPCRdb generic numbers in the B-factor field of CA atoms

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MAIN TEMPLATE

κ receptor (sequence similarity: 45%) PDB: 6B73

TEMPLATES

6B73 (κ receptor)
4DJH (κ receptor)
5VBL (apelin receptor)
7MBX (CCK1 receptor)
None
Main template (%) Additional templates (%) No template - freely modelled (%)
Backbone 78.5 11.6 9.9
Side-chains 31.1 55.3 13.7

Number of backbone templates: 4
Number of rotamer templates: 47

Segment Seq.num. AA GPCRdb# Backbone PDB Rotamer PDB
N-term 33 A - - - - -
N-term 34 P - - - - -
N-term 35 S - κ receptor 6B73 κ receptor 6B73
N-term 36 A - κ receptor 6B73 κ receptor 6B73
N-term 37 G - κ receptor 6B73 κ receptor 6B73
TM1 38 A 1.30x30 κ receptor 6B73 κ receptor 6B73
TM1 39 R 1.31x31 κ receptor 6B73 CysLT1 receptor 6RZ4
TM1 40 A 1.32x32 κ receptor 6B73 μ receptor 5C1M
TM1 41 V 1.33x33 κ receptor 6B73 κ receptor 6B73
TM1 42 L 1.34x34 κ receptor 6B73 CCR5 7O7F
TM1 43 V 1.35x35 κ receptor 6B73 CXCR2 6LFO
TM1 44 P 1.36x36 κ receptor 6B73 AT1 receptor 6DO1
TM1 45 V 1.37x37 κ receptor 6B73 H1 receptor 7DFL
TM1 46 L 1.38x38 κ receptor 6B73 μ receptor 5C1M
TM1 47 Y 1.39x39 κ receptor 6B73 κ receptor 6B73
TM1 48 L 1.40x40 κ receptor 6B73 CB1 receptor 5XRA
TM1 49 L 1.41x41 κ receptor 6B73 CCK1 receptor 7MBX
TM1 50 V 1.42x42 κ receptor 6B73 κ receptor 6B73
TM1 51 C 1.43x43 κ receptor 6B73 μ receptor 5C1M
TM1 52 A 1.44x44 κ receptor 6B73 δ receptor 6PT2
TM1 53 A 1.45x45 κ receptor 6B73 β2-adrenoceptor 3SN6
TM1 54 G 1.46x46 κ receptor 6B73 κ receptor 6B73
TM1 55 L 1.47x47 κ receptor 6B73 κ receptor 6B73
TM1 56 G 1.48x48 κ receptor 6B73 5-HT2B receptor 5TUD
TM1 57 G 1.49x49 κ receptor 6B73 κ receptor 6B73
TM1 58 N 1.50x50 κ receptor 6B73 κ receptor 6B73
TM1 59 T 1.51x51 κ receptor 6B73 CCK1 receptor 7MBX
TM1 60 L 1.52x52 κ receptor 6B73 κ receptor 6B73
TM1 61 V 1.53x53 κ receptor 6B73 κ receptor 6B73
TM1 62 I 1.54x54 κ receptor 6B73 CCK1 receptor 7MBX
TM1 63 Y 1.55x55 κ receptor 6B73 μ receptor 5C1M
TM1 64 V 1.56x56 κ receptor 6B73 κ receptor 6B73
TM1 65 V 1.57x57 κ receptor 6B73 OX2 receptor 7L1V
TM1 66 L 1.58x58 κ receptor 6B73 CXCR2 6LFO
TM1 67 R 1.59x59 κ receptor 6B73 μ receptor 5C1M
TM1 68 F 1.60x60 κ receptor 6B73 - -
ICL1 69 A 12.48x48 - - - -
ICL1 70 K 12.49x49 κ receptor 4DJH 5-HT2C receptor 6BQG
ICL1 71 M 12.50x50 κ receptor 4DJH κ receptor 4DJH
ICL1 72 K 12.51x51 - - - -
TM2 73 T 2.37x37 κ receptor 6B73 κ receptor 6B73
TM2 74 V 2.38x38 κ receptor 6B73 AT1 receptor 6DO1
TM2 75 T 2.39x39 κ receptor 6B73 κ receptor 6B73
TM2 76 N 2.40x40 κ receptor 6B73 κ receptor 6B73
TM2 77 I 2.41x41 κ receptor 6B73 κ receptor 6B73
TM2 78 Y 2.42x42 κ receptor 6B73 κ receptor 6B73
TM2 79 I 2.43x43 κ receptor 6B73 κ receptor 6B73
TM2 80 L 2.44x44 κ receptor 6B73 AT1 receptor 6DO1
TM2 81 N 2.45x45 κ receptor 6B73 κ receptor 6B73
TM2 82 L 2.46x46 κ receptor 6B73 κ receptor 6B73
TM2 83 A 2.47x47 κ receptor 6B73 κ receptor 6B73
TM2 84 V 2.48x48 κ receptor 6B73 CCK1 receptor 7MBX
TM2 85 A 2.49x49 κ receptor 6B73 κ receptor 6B73
TM2 86 D 2.50x50 κ receptor 6B73 κ receptor 6B73
TM2 87 V 2.51x51 κ receptor 6B73 OX2 receptor 7L1V
TM2 88 L 2.52x52 κ receptor 6B73 κ receptor 6B73
TM2 89 Y 2.53x53 κ receptor 6B73 P2Y1 receptor 4XNW
TM2 90 M 2.54x54 κ receptor 6B73 - -
TM2 91 L 2.55x55 κ receptor 6B73 AT1 receptor 6DO1
TM2 92 G 2.56x56 κ receptor 6B73 Rhodopsin 4X1H
TM2 93 L 2.57x57 κ receptor 6B73 μ receptor 5C1M
TM2 94 P 2.58x58 κ receptor 6B73 κ receptor 6B73
TM2 95 F 2.59x59 κ receptor 6B73 κ receptor 6B73
TM2 96 L 2.60x60 κ receptor 6B73 FPR2/ALX 6OMM
TM2 97 A 2.61x61 κ receptor 6B73 AT1 receptor 6DO1
TM2 98 T 2.62x62 κ receptor 6B73 κ receptor 6B73
TM2 99 Q 2.63x63 κ receptor 6B73 TP receptor 6IIV
TM2 100 N 2.64x64 κ receptor 6B73 CCK1 receptor 7MBX
TM2 101 A 2.65x65 κ receptor 6B73 AT1 receptor 6DO1
TM2 102 A 2.66x66 κ receptor 6B73 D1 receptor 7JVQ
ECL1 103 S - - - - -
ECL1 104 F 23.49x49 κ receptor 4DJH D1 receptor 7JVQ
ECL1 105 W 23.50x50 κ receptor 4DJH κ receptor 4DJH
ECL1 106 P 23.51x51 κ receptor 4DJH κ receptor 4DJH
ECL1 107 F 23.52x52 - - - -
TM3 108 G 3.21x21 κ receptor 6B73 κ receptor 6B73
TM3 109 P 3.22x22 κ receptor 6B73 Rhodopsin 4X1H
TM3 110 V 3.23x23 κ receptor 6B73 κ receptor 6B73
TM3 111 L 3.24x24 κ receptor 6B73 κ receptor 6B73
TM3 112 C 3.25x25 κ receptor 6B73 κ receptor 6B73
TM3 113 R 3.26x26 κ receptor 6B73 V2 receptor 7KH0
TM3 114 L 3.27x27 κ receptor 6B73 CCR5 7O7F
TM3 115 V 3.28x28 κ receptor 6B73 κ receptor 6B73
TM3 116 M 3.29x29 κ receptor 6B73 D4 receptor 6IQL
TM3 117 T 3.30x30 κ receptor 6B73 D3 receptor 7CMV
TM3 118 L 3.31x31 κ receptor 6B73 OX2 receptor 7L1V
TM3 119 D 3.32x32 κ receptor 6B73 κ receptor 6B73
TM3 120 G 3.33x33 κ receptor 6B73 CCK1 receptor 7MBX
TM3 121 V 3.34x34 κ receptor 6B73 OX2 receptor 7L1V
TM3 122 N 3.35x35 κ receptor 6B73 κ receptor 6B73
TM3 123 Q 3.36x36 κ receptor 6B73 - -
TM3 124 F 3.37x37 κ receptor 6B73 κ receptor 6B73
TM3 125 T 3.38x38 κ receptor 6B73 κ receptor 6B73
TM3 126 S 3.39x39 κ receptor 6B73 κ receptor 6B73
TM3 127 V 3.40x40 κ receptor 6B73 AT1 receptor 6DO1
TM3 128 F 3.41x41 κ receptor 6B73 κ receptor 6B73
TM3 129 C 3.42x42 κ receptor 6B73 GPR52 6LI3
TM3 130 L 3.43x43 κ receptor 6B73 κ receptor 6B73
TM3 131 T 3.44x44 κ receptor 6B73 κ receptor 6B73
TM3 132 V 3.45x45 κ receptor 6B73 β1-adrenoceptor 7BU7
TM3 133 M 3.46x46 κ receptor 6B73 κ receptor 6B73
TM3 134 S 3.47x47 κ receptor 6B73 κ receptor 6B73
TM3 135 V 3.48x48 κ receptor 6B73 κ receptor 6B73
TM3 136 D 3.49x49 κ receptor 6B73 κ receptor 6B73
TM3 137 R 3.50x50 κ receptor 6B73 κ receptor 6B73
TM3 138 Y 3.51x51 κ receptor 6B73 κ receptor 6B73
TM3 139 L 3.52x52 κ receptor 6B73 AT1 receptor 6DO1
TM3 140 A 3.53x53 κ receptor 6B73 κ receptor 6B73
TM3 141 V 3.54x54 κ receptor 6B73 κ receptor 6B73
TM3 142 V 3.55x55 κ receptor 6B73 AT1 receptor 6DO1
TM3 143 H 3.56x56 κ receptor 6B73 κ receptor 6B73
ICL2 144 P 34.50x50 κ receptor 6B73 κ receptor 6B73
ICL2 145 L 34.51x51 κ receptor 6B73 CCK1 receptor 7MBX
ICL2 146 S 34.52x52 κ receptor 6B73 Rhodopsin 5W0P
ICL2 147 S 34.53x53 κ receptor 6B73 AT1 receptor 6DO1
ICL2 148 A 34.54x54 κ receptor 6B73 5-ht1E receptor 7E33
ICL2 149 R 34.55x55 κ receptor 6B73 D1 receptor 7JVQ
ICL2 150 W 34.56x56 κ receptor 6B73 CCK1 receptor 7MBX
ICL2 151 R 34.57x57 κ receptor 6B73 κ receptor 6B73
TM4 152 R 4.38x38 κ receptor 6B73 OT receptor 6TPK
TM4 153 P 4.39x39 κ receptor 6B73 κ receptor 6B73
TM4 154 R 4.40x40 κ receptor 6B73 μ receptor 5C1M
TM4 155 V 4.41x41 κ receptor 6B73 AT1 receptor 6DO1
TM4 156 A 4.42x42 κ receptor 6B73 κ receptor 6B73
TM4 157 K 4.43x43 κ receptor 6B73 κ receptor 6B73
TM4 158 L 4.44x44 κ receptor 6B73 δ receptor 6PT2
TM4 159 A 4.45x45 κ receptor 6B73 β3-adrenoceptor 7DH5
TM4 160 S 4.46x46 κ receptor 6B73 CCR5 7O7F
TM4 161 A 4.47x47 κ receptor 6B73 CCK1 receptor 7MBX
TM4 162 A 4.48x48 κ receptor 6B73 CCK1 receptor 7MBX
TM4 163 A 4.49x49 κ receptor 6B73 D1 receptor 7JVQ
TM4 164 W 4.50x50 κ receptor 6B73 κ receptor 6B73
TM4 165 V 4.51x51 κ receptor 6B73 δ receptor 6PT2
TM4 166 L 4.52x52 κ receptor 6B73 κ receptor 6B73
TM4 167 S 4.53x53 κ receptor 6B73 κ receptor 6B73
TM4 168 L 4.54x54 κ receptor 6B73 CXCR2 6LFO
TM4 169 C 4.55x55 κ receptor 6B73 5-HT1D receptor 7E32
TM4 170 M 4.56x56 κ receptor 6B73 LPA1 receptor 4Z35
TM4 171 S 4.57x57 apelin receptor 5VBL AT1 receptor 6DO1
TM4 172 L 4.58x59 apelin receptor 5VBL AT1 receptor 6DO1
TM4 173 P 4.59x60 κ receptor 6B73 AT1 receptor 6DO1
TM4 174 L 4.60x61 κ receptor 6B73 D3 receptor 7CMV
TM4 175 L 4.61x62 κ receptor 6B73 CXCR2 6LFO
TM4 176 V 4.62x63 κ receptor 6B73 5-HT2C receptor 6BQG
TM4 177 F 4.63x64 κ receptor 6B73 CCR5 7F1S
TM4 178 A 4.64x65 apelin receptor 5VBL CXCR4 3ODU
ECL2 179 D - - - - -
ECL2 180 V - - - - -
ECL2 181 Q - - - - -
ECL2 182 E - - - - -
ECL2 183 G - - - - -
ECL2 184 G - - - - -
ECL2 185 T - - - - -
ECL2 186 C 45.50x50 κ receptor 6B73 κ receptor 6B73
ECL2 187 N 45.51x51 κ receptor 6B73 - -
ECL2 188 A 45.52x52 κ receptor 6B73 V2 receptor 7KH0
ECL2 189 S - - - - -
ECL2 190 W - - - - -
ECL2 191 P - - - - -
ECL2 192 E - - - - -
TM5 193 P 5.30x31 κ receptor 4DJH - -
TM5 194 V 5.31x32 κ receptor 4DJH - -
TM5 195 G 5.32x33 κ receptor 4DJH PAR1 3VW7
TM5 196 L 5.33x34 κ receptor 6B73 CXCR4 3ODU
TM5 197 W 5.34x35 κ receptor 6B73 κ receptor 6B73
TM5 198 G 5.35x36 κ receptor 6B73 NOP receptor 5DHG
TM5 199 A 5.36x37 κ receptor 6B73 α2B-adrenoceptor 6K42
TM5 200 V 5.37x38 κ receptor 6B73 δ receptor 6PT2
TM5 201 F 5.38x39 κ receptor 6B73 D3 receptor 7CMV
TM5 202 I 5.39x40 κ receptor 6B73 α2B-adrenoceptor 6K42
TM5 203 I 5.40x41 κ receptor 6B73 κ receptor 6B73
TM5 204 Y 5.41x42 κ receptor 6B73 D3 receptor 7CMV
TM5 205 T 5.42x43 κ receptor 6B73 H1 receptor 7DFL
TM5 206 A 5.43x44 κ receptor 6B73 H1 receptor 7DFL
TM5 207 V 5.44x45 κ receptor 6B73 β1-adrenoceptor 7BU7
TM5 208 L 5.45x46 κ receptor 6B73 AT1 receptor 6DO1
TM5 209 G 5.46x461 κ receptor 6B73 AT1 receptor 6DO1
TM5 210 F 5.47x47 κ receptor 6B73 κ receptor 6B73
TM5 211 F 5.48x48 κ receptor 6B73 5-HT2B receptor 5TUD
TM5 212 A 5.49x49 κ receptor 6B73 OX2 receptor 7L1V
TM5 213 P 5.50x50 κ receptor 6B73 κ receptor 6B73
TM5 214 L 5.51x51 κ receptor 6B73 OX2 receptor 7L1V
TM5 215 L 5.52x52 κ receptor 6B73 κ receptor 6B73
TM5 216 V 5.53x53 κ receptor 6B73 CCK1 receptor 7MBX
TM5 217 I 5.54x54 κ receptor 6B73 κ receptor 6B73
TM5 218 C 5.55x55 κ receptor 6B73 M1 receptor 6OIJ
TM5 219 L 5.56x56 κ receptor 6B73 OX2 receptor 7L1V
TM5 220 C 5.57x57 κ receptor 6B73 κ receptor 6B73
TM5 221 Y 5.58x58 κ receptor 6B73 κ receptor 6B73
TM5 222 L 5.59x59 κ receptor 6B73 OX2 receptor 7L1V
TM5 223 L 5.60x60 κ receptor 6B73 κ receptor 6B73
TM5 224 I 5.61x61 κ receptor 6B73 AT1 receptor 6DO1
TM5 225 V 5.62x62 κ receptor 6B73 CCR6 6WWZ
TM5 226 V 5.63x63 κ receptor 6B73 D3 receptor 7CMV
TM5 227 K 5.64x64 κ receptor 6B73 OX2 receptor 7L1V
TM5 228 V 5.65x65 κ receptor 6B73 H1 receptor 7DFL
TM5 229 R 5.66x66 κ receptor 6B73 δ receptor 6PT2
TM5 230 A 5.67x67 κ receptor 6B73 V2 receptor 7KH0
TM5 231 A 5.68x68 CCK1 receptor 7MBX AT1 receptor 6DO1
TM5 232 G 5.69x69 CCK1 receptor 7MBX FPR2/ALX 6OMM
TM5 233 V 5.70x70 CCK1 receptor 7MBX CB1 receptor 6N4B
TM5 234 R 5.71x71 CCK1 receptor 7MBX D1 receptor 7JVQ
TM5 235 V 5.72x72 CCK1 receptor 7MBX D2 receptor 7JVR
ICL3 236 G - - - - -
ICL3 237 C - - - - -
ICL3 238 V - - - - -
ICL3 239 R - - - - -
ICL3 240 R - - - - -
ICL3 241 R - - - - -
TM6 242 S 6.29x29 κ receptor 6B73 δ receptor 6PT2
TM6 243 E 6.30x30 κ receptor 6B73 β1-adrenoceptor 7BU7
TM6 244 R 6.31x31 κ receptor 6B73 μ receptor 5C1M
TM6 245 K 6.32x32 κ receptor 6B73 OX2 receptor 7L1V
TM6 246 V 6.33x33 κ receptor 6B73 CCK1 receptor 7MBX
TM6 247 T 6.34x34 κ receptor 6B73 κ receptor 6B73
TM6 248 R 6.35x35 κ receptor 6B73 κ receptor 6B73
TM6 249 M 6.36x36 κ receptor 6B73 μ receptor 5C1M
TM6 250 V 6.37x37 κ receptor 6B73 κ receptor 6B73
TM6 251 L 6.38x38 κ receptor 6B73 κ receptor 6B73
TM6 252 V 6.39x39 κ receptor 6B73 κ receptor 6B73
TM6 253 V 6.40x40 κ receptor 6B73 κ receptor 6B73
TM6 254 V 6.41x41 κ receptor 6B73 κ receptor 6B73
TM6 255 L 6.42x42 κ receptor 6B73 AT1 receptor 6DO1
TM6 256 V 6.43x43 κ receptor 6B73 κ receptor 6B73
TM6 257 F 6.44x44 κ receptor 6B73 κ receptor 6B73
TM6 258 A 6.45x45 κ receptor 6B73 OX2 receptor 7L1V
TM6 259 G 6.46x46 κ receptor 6B73 NOP receptor 5DHG
TM6 260 C 6.47x47 κ receptor 6B73 κ receptor 6B73
TM6 261 W 6.48x48 κ receptor 6B73 κ receptor 6B73
TM6 262 L 6.49x49 κ receptor 6B73 OX2 receptor 7L1V
TM6 263 P 6.50x50 κ receptor 6B73 κ receptor 6B73
TM6 264 F 6.51x51 κ receptor 6B73 β1-adrenoceptor 7BU7
TM6 265 F 6.52x52 κ receptor 6B73 CCK1 receptor 7MBX
TM6 266 T 6.53x53 κ receptor 6B73 CysLT2 receptor 6RZ6
TM6 267 V 6.54x54 κ receptor 6B73 CCR5 7O7F
TM6 268 N 6.55x55 κ receptor 6B73 CCK1 receptor 7MBX
TM6 269 I 6.56x56 κ receptor 6B73 μ receptor 5C1M
TM6 270 V 6.57x57 κ receptor 6B73 κ receptor 6B73
TM6 271 N 6.58x58 κ receptor 6B73 CCR5 7O7F
TM6 272 L 6.59x59 κ receptor 6B73 A1 receptor 6D9H
TM6 273 A 6.60x60 κ receptor 6B73 CCR6 6WWZ
TM6 274 V 6.61x61 κ receptor 6B73 δ receptor 6PT2
ECL3 275 A - - - - -
ECL3 276 L - κ receptor 6B73 - -
ECL3 277 P - κ receptor 6B73 - -
ECL3 278 Q - κ receptor 6B73 - -
TM7 279 E 7.28x27 κ receptor 6B73 - -
TM7 280 P 7.29x28 κ receptor 6B73 δ receptor 6PT2
TM7 281 A 7.30x29 κ receptor 6B73 κ receptor 6B73
TM7 282 S 7.31x30 κ receptor 6B73 - -
TM7 283 A 7.32x31 κ receptor 6B73 OT receptor 6TPK
TM7 284 G 7.33x32 κ receptor 6B73 α2B-adrenoceptor 6K41
TM7 285 L 7.34x33 κ receptor 6B73 β1-adrenoceptor 7BU7
TM7 286 Y 7.35x34 κ receptor 6B73 κ receptor 6B73
TM7 287 F 7.36x35 κ receptor 6B73 GPR52 6LI3
TM7 288 F 7.37x36 κ receptor 6B73 κ receptor 6B73
TM7 289 V 7.38x37 κ receptor 6B73 D4 receptor 6IQL
TM7 290 V 7.39x38 κ receptor 6B73 D1 receptor 7JVQ
TM7 291 I 7.40x39 κ receptor 6B73 CXCR2 6LFO
TM7 292 L 7.41x40 κ receptor 6B73 κ receptor 6B73
TM7 293 S 7.42x41 κ receptor 6B73 CCK1 receptor 7MBX
TM7 294 Y 7.43x42 κ receptor 6B73 κ receptor 6B73
TM7 295 A 7.44x43 κ receptor 6B73 OX2 receptor 7L1V
TM7 296 N 7.45x45 κ receptor 6B73 κ receptor 6B73
TM7 297 S 7.46x46 κ receptor 6B73 κ receptor 6B73
TM7 298 C 7.47x47 κ receptor 6B73 μ receptor 5C1M
TM7 299 A 7.48x48 κ receptor 6B73 OX2 receptor 7L1V
TM7 300 N 7.49x49 κ receptor 6B73 κ receptor 6B73
TM7 301 P 7.50x50 κ receptor 6B73 κ receptor 6B73
TM7 302 V 7.51x51 κ receptor 6B73 μ receptor 6DDF
TM7 303 L 7.52x52 κ receptor 4DJH κ receptor 4DJH
TM7 304 Y 7.53x53 κ receptor 4DJH κ receptor 4DJH
TM7 305 G 7.54x54 κ receptor 4DJH AT1 receptor 6DO1
TM7 306 F 7.55x55 κ receptor 4DJH κ receptor 4DJH
TM7 307 L 7.56x56 κ receptor 4DJH κ receptor 4DJH
H8 308 S 8.47x47 κ receptor 4DJH OX2 receptor 7L1V
H8 309 D 8.48x48 κ receptor 4DJH NK1 receptor 6HLP
H8 310 N 8.49x49 κ receptor 4DJH κ receptor 4DJH
H8 311 F 8.50x50 κ receptor 4DJH κ receptor 4DJH
H8 312 R 8.51x51 κ receptor 4DJH CCK1 receptor 7MBX
H8 313 Q 8.52x52 κ receptor 4DJH 5-HT1D receptor 7E32
H8 314 S 8.53x53 κ receptor 4DJH CB2 receptor 6PT0
H8 315 F 8.54x54 κ receptor 4DJH κ receptor 4DJH
H8 316 Q 8.55x55 κ receptor 4DJH β1-adrenoceptor 7BU7
H8 317 K 8.56x56 κ receptor 4DJH CXCR2 6LFO
H8 318 V 8.57x57 κ receptor 4DJH AT2 receptor 5UNG
H8 319 L 8.58x58 κ receptor 4DJH AT1 receptor 6DO1
H8 320 C 8.59x59 κ receptor 4DJH β2-adrenoceptor 3SN6
C-term 321 L - - - - -
C-term 322 R - - - - -
C-term 323 K - - - - -
C-term 324 G - - - - -
C-term 325 S - - - - -