CELSR3 homology model
PROTEIN CLASS
Class B2 (Adhesion)
RECEPTOR
SPECIES
Homo sapiens
STATE
Inactive
VERSION
2022-06-19
MODEL
MAIN TEMPLATE
TEMPLATES
7WU2 (ADGRD1)
4K5Y (CRF1 receptor)
6PB1 (CRF2 receptor)
7WUJ (ADGRG4)
None
4K5Y (CRF1 receptor)
6PB1 (CRF2 receptor)
7WUJ (ADGRG4)
None
| Main template (%) | Additional templates (%) | No template - freely modelled (%) | |
|---|---|---|---|
| Backbone | 72.6 | 20.0 | 7.4 |
| Side-chains | 15.9 | 47.8 | 36.3 |
Number of backbone templates: 4
Number of rotamer templates: 17
| Segment | Seq.num. | AA | GPCRdb# | Backbone | PDB | Rotamer | PDB |
|---|---|---|---|---|---|---|---|
| N-term | 2527 | S | - | ADGRD1 | 7WU2 | ADGRD1 | 7WU2 |
| N-term | 2528 | P | - | ADGRD1 | 7WU2 | ADGRD1 | 7WU2 |
| N-term | 2529 | R | - | ADGRD1 | 7WU2 | ADGRD1 | 7WU2 |
| N-term | 2530 | E | - | ADGRD1 | 7WU2 | ADGRD1 | 7WU2 |
| N-term | 2531 | R | - | ADGRD1 | 7WU2 | ADGRD1 | 7WU2 |
| TM1 | 2532 | L | 1.32x32 | ADGRD1 | 7WU2 | - | - |
| TM1 | 2533 | E | 1.33x33 | ADGRD1 | 7WU2 | GLP-1 receptor | 7DUQ |
| TM1 | 2534 | G | 1.34x34 | ADGRD1 | 7WU2 | ADGRD1 | 7WU2 |
| TM1 | 2535 | D | 1.35x35 | ADGRD1 | 7WU2 | - | - |
| TM1 | 2536 | L | 1.36x36 | ADGRD1 | 7WU2 | secretin receptor | 6WZG |
| TM1 | 2537 | E | 1.37x37 | CRF1 receptor | 4K5Y | GIP receptor | 7FIN |
| TM1 | 2538 | L | 1.38x38 | CRF1 receptor | 4K5Y | ADGRL3 | 7SF7 |
| TM1 | 2539 | L | 1.39x39 | CRF1 receptor | 4K5Y | ADGRD1 | 7WU2 |
| TM1 | 2540 | A | 1.40x40 | CRF1 receptor | 4K5Y | ADGRG4 | 7WUJ |
| TM1 | 2541 | V | 1.41x41 | CRF1 receptor | 4K5Y | ADGRL3 | 7SF7 |
| TM1 | 2542 | F | 1.42x42 | CRF1 receptor | 4K5Y | - | - |
| TM1 | 2543 | T | 1.43x43 | CRF1 receptor | 4K5Y | ADGRL3 | 7SF7 |
| TM1 | 2544 | H | 1.44x44 | CRF1 receptor | 4K5Y | - | - |
| TM1 | 2545 | V | 1.45x45 | CRF1 receptor | 4K5Y | ADGRD1 | 7WU2 |
| TM1 | 2546 | V | 1.46x46 | CRF1 receptor | 4K5Y | - | - |
| TM1 | 2547 | V | 1.47x47 | CRF1 receptor | 4K5Y | - | - |
| TM1 | 2548 | A | 1.48x48 | CRF1 receptor | 4K5Y | GLP-1 receptor | 7DUQ |
| TM1 | 2549 | V | 1.49x49 | CRF1 receptor | 4K5Y | CRF2 receptor | 6PB1 |
| TM1 | 2550 | S | 1.50x50 | CRF1 receptor | 4K5Y | CRF1 receptor | 4K5Y |
| TM1 | 2551 | V | 1.51x51 | CRF1 receptor | 4K5Y | ADGRD1 | 7WU2 |
| TM1 | 2552 | A | 1.52x52 | CRF1 receptor | 4K5Y | CRF2 receptor | 6PB1 |
| TM1 | 2553 | A | 1.53x53 | CRF1 receptor | 4K5Y | CRF1 receptor | 4K5Y |
| TM1 | 2554 | L | 1.54x54 | CRF1 receptor | 4K5Y | CRF1 receptor | 4K5Y |
| TM1 | 2555 | V | 1.55x55 | CRF1 receptor | 4K5Y | ADGRD1 | 7WU2 |
| TM1 | 2556 | L | 1.56x56 | CRF1 receptor | 4K5Y | ADGRF1 | 7WU3 |
| TM1 | 2557 | T | 1.57x57 | CRF1 receptor | 4K5Y | ADGRD1 | 7WU2 |
| TM1 | 2558 | A | 1.58x58 | CRF1 receptor | 4K5Y | - | - |
| TM1 | 2559 | A | 1.59x59 | CRF1 receptor | 4K5Y | GLP-1 receptor | 7DUQ |
| TM1 | 2560 | I | 1.60x60 | CRF1 receptor | 4K5Y | ADGRF1 | 7WU3 |
| TM1 | 2561 | L | 1.61x61 | CRF1 receptor | 4K5Y | secretin receptor | 6WZG |
| TM1 | 2562 | L | 1.62x62 | CRF1 receptor | 4K5Y | CRF1 receptor | 4K5Y |
| TM1 | 2563 | S | 1.63x63 | CRF1 receptor | 4K5Y | - | - |
| TM1 | 2564 | L | 1.64x64 | CRF1 receptor | 4K5Y | CRF2 receptor | 6PB1 |
| ICL1 | 2565 | R | 12.48x48 | - | - | - | - |
| ICL1 | 2566 | S | 12.49x49 | CRF2 receptor | 6PB1 | CRF2 receptor | 6PB1 |
| ICL1 | 2567 | L | 12.50x50 | CRF2 receptor | 6PB1 | calcitonin receptor-like receptor | 6UVA |
| ICL1 | 2568 | K | 12.51x51 | - | - | - | - |
| TM2 | 2569 | S | 2.44x44 | CRF1 receptor | 4K5Y | - | - |
| TM2 | 2570 | N | 2.45x45 | CRF1 receptor | 4K5Y | - | - |
| TM2 | 2571 | V | 2.46x46 | CRF1 receptor | 4K5Y | - | - |
| TM2 | 2572 | R | 2.47x47 | CRF1 receptor | 4K5Y | ADGRF1 | 7WU3 |
| TM2 | 2573 | G | 2.48x48 | CRF1 receptor | 4K5Y | - | - |
| TM2 | 2574 | I | 2.49x49 | CRF1 receptor | 4K5Y | CRF1 receptor | 4K5Y |
| TM2 | 2575 | H | 2.50x50 | CRF1 receptor | 4K5Y | CRF1 receptor | 4K5Y |
| TM2 | 2576 | A | 2.51x51 | CRF1 receptor | 4K5Y | ADGRD1 | 7WU2 |
| TM2 | 2577 | N | 2.52x52 | CRF1 receptor | 4K5Y | CRF1 receptor | 4K5Y |
| TM2 | 2578 | V | 2.53x53 | CRF1 receptor | 4K5Y | - | - |
| TM2 | 2579 | A | 2.54x54 | CRF1 receptor | 4K5Y | ADGRF1 | 7WU3 |
| TM2 | 2580 | A | 2.55x55 | CRF1 receptor | 4K5Y | GLP-1 receptor | 7DUQ |
| TM2 | 2581 | A | 2.56x56 | CRF1 receptor | 4K5Y | CRF1 receptor | 4K5Y |
| TM2 | 2582 | L | 2.57x57 | CRF1 receptor | 4K5Y | ADGRL3 | 7SF7 |
| TM2 | 2583 | G | 2.58x58 | CRF1 receptor | 4K5Y | - | - |
| TM2 | 2584 | V | 2.59x59 | CRF1 receptor | 4K5Y | ADGRD1 | 7WU2 |
| TM2 | 2585 | A | 2.60x60 | CRF1 receptor | 4K5Y | ADGRD1 | 7WU2 |
| TM2 | 2586 | E | 2.61x61 | CRF1 receptor | 4K5Y | ADGRL3 | 7SF7 |
| TM2 | 2587 | L | 2.62x62 | CRF1 receptor | 4K5Y | ADGRL3 | 7SF7 |
| TM2 | 2588 | L | 2.63x63 | CRF1 receptor | 4K5Y | ADGRD1 | 7WU2 |
| TM2 | 2589 | F | 2.64x64 | CRF1 receptor | 4K5Y | ADGRL3 | 7SF7 |
| TM2 | 2590 | L | 2.65x65 | CRF1 receptor | 4K5Y | ADGRD1 | 7WU2 |
| TM2 | 2591 | L | 2.66x66 | CRF1 receptor | 4K5Y | CRF2 receptor | 6PB1 |
| TM2 | 2592 | G | 2.67x67 | CRF1 receptor | 4K5Y | ADGRL3 | 7SF7 |
| TM2 | 2593 | I | 2.68x68 | CRF1 receptor | 4K5Y | - | - |
| TM2 | 2594 | H | 2.69x69 | CRF1 receptor | 4K5Y | - | - |
| TM2 | 2595 | R | 2.70x70 | CRF1 receptor | 4K5Y | - | - |
| ECL1 | 2596 | T | - | - | - | - | - |
| ECL1 | 2597 | H | - | - | - | - | - |
| ECL1 | 2598 | N | - | - | - | - | - |
| ECL1 | 2599 | Q | - | - | - | - | - |
| TM3 | 2600 | L | 3.27x27 | CRF1 receptor | 4K5Y | GLP-1 receptor | 7DUQ |
| TM3 | 2601 | V | 3.28x28 | CRF1 receptor | 4K5Y | ADGRF1 | 7WU3 |
| TM3 | 2602 | C | 3.29x29 | CRF1 receptor | 4K5Y | CRF1 receptor | 4K5Y |
| TM3 | 2603 | T | 3.30x30 | CRF1 receptor | 4K5Y | ADGRF1 | 7WU3 |
| TM3 | 2604 | A | 3.31x31 | CRF1 receptor | 4K5Y | ADGRF1 | 7WU3 |
| TM3 | 2605 | V | 3.32x32 | CRF1 receptor | 4K5Y | CRF1 receptor | 4K5Y |
| TM3 | 2606 | A | 3.33x33 | CRF1 receptor | 4K5Y | ADGRD1 | 7WU2 |
| TM3 | 2607 | I | 3.34x34 | CRF1 receptor | 4K5Y | ADGRG1 | 7SF8 |
| TM3 | 2608 | L | 3.35x35 | CRF1 receptor | 4K5Y | ADGRD1 | 7WU2 |
| TM3 | 2609 | L | 3.36x36 | CRF1 receptor | 4K5Y | ADGRD1 | 7WU2 |
| TM3 | 2610 | H | 3.37x37 | CRF1 receptor | 4K5Y | ADGRD1 | 7WU2 |
| TM3 | 2611 | Y | 3.38x38 | CRF1 receptor | 4K5Y | CRF1 receptor | 4K5Y |
| TM3 | 2612 | F | 3.39x39 | CRF1 receptor | 4K5Y | CRF1 receptor | 4K5Y |
| TM3 | 2613 | F | 3.40x40 | CRF1 receptor | 4K5Y | ADGRD1 | 7WU2 |
| TM3 | 2614 | L | 3.41x41 | CRF1 receptor | 4K5Y | ADGRD1 | 7WU2 |
| TM3 | 2615 | S | 3.42x42 | CRF1 receptor | 4K5Y | ADGRD1 | 7WU2 |
| TM3 | 2616 | T | 3.43x43 | CRF1 receptor | 4K5Y | - | - |
| TM3 | 2617 | F | 3.44x44 | CRF1 receptor | 4K5Y | CRF1 receptor | 4K5Y |
| TM3 | 2618 | A | 3.45x45 | CRF1 receptor | 4K5Y | ADGRD1 | 7WU2 |
| TM3 | 2619 | W | 3.46x46 | CRF1 receptor | 4K5Y | CRF1 receptor | 4K5Y |
| TM3 | 2620 | L | 3.47x47 | CRF1 receptor | 4K5Y | secretin receptor | 6WZG |
| TM3 | 2621 | F | 3.48x48 | CRF1 receptor | 4K5Y | CRF1 receptor | 4K5Y |
| TM3 | 2622 | V | 3.49x49 | CRF1 receptor | 4K5Y | ADGRD1 | 7WU2 |
| TM3 | 2623 | Q | 3.50x50 | CRF1 receptor | 4K5Y | - | - |
| TM3 | 2624 | G | 3.51x51 | CRF1 receptor | 4K5Y | CRF1 receptor | 4K5Y |
| TM3 | 2625 | L | 3.52x52 | CRF1 receptor | 4K5Y | ADGRD1 | 7WU2 |
| TM3 | 2626 | H | 3.53x53 | CRF1 receptor | 4K5Y | ADGRD1 | 7WU2 |
| TM3 | 2627 | L | 3.54x54 | CRF1 receptor | 4K5Y | CRF1 receptor | 4K5Y |
| TM3 | 2628 | Y | 3.55x55 | CRF1 receptor | 4K5Y | ADGRD1 | 7WU2 |
| TM3 | 2629 | R | 3.56x56 | CRF1 receptor | 4K5Y | ADGRG1 | 7SF8 |
| TM3 | 2630 | M | 3.57x57 | CRF1 receptor | 4K5Y | ADGRD1 | 7WU2 |
| TM3 | 2631 | Q | 3.58x58 | CRF1 receptor | 4K5Y | - | - |
| TM3 | 2632 | V | 3.59x59 | CRF1 receptor | 4K5Y | CRF1 receptor | 4K5Y |
| TM3 | 2633 | E | 3.60x60 | CRF1 receptor | 4K5Y | - | - |
| ICL2 | 2634 | P | - | - | - | - | - |
| ICL2 | 2635 | R | - | ADGRD1 | 7WU2 | - | - |
| ICL2 | 2636 | N | - | ADGRD1 | 7WU2 | - | - |
| ICL2 | 2637 | V | - | ADGRD1 | 7WU2 | - | - |
| ICL2 | 2638 | D | - | ADGRD1 | 7WU2 | - | - |
| ICL2 | 2639 | R | - | ADGRD1 | 7WU2 | - | - |
| ICL2 | 2640 | G | - | - | - | - | - |
| TM4 | 2641 | A | 4.41x42 | CRF1 receptor | 4K5Y | - | - |
| TM4 | 2642 | M | 4.42x43 | CRF1 receptor | 4K5Y | ADGRF1 | 7WU3 |
| TM4 | 2643 | R | 4.43x44 | CRF1 receptor | 4K5Y | ADGRD1 | 7WU2 |
| TM4 | 2644 | F | 4.44x45 | CRF1 receptor | 4K5Y | - | - |
| TM4 | 2645 | Y | 4.45x46 | CRF1 receptor | 4K5Y | ADGRD1 | 7WU2 |
| TM4 | 2646 | H | 4.46x47 | CRF1 receptor | 4K5Y | - | - |
| TM4 | 2647 | A | 4.47x48 | CRF1 receptor | 4K5Y | secretin receptor | 6WZG |
| TM4 | 2648 | L | 4.48x49 | CRF1 receptor | 4K5Y | ADGRF1 | 7WU3 |
| TM4 | 2649 | G | 4.49x491 | CRF1 receptor | 4K5Y | CRF1 receptor | 4K5Y |
| TM4 | 2650 | W | 4.50x50 | CRF1 receptor | 4K5Y | CRF1 receptor | 4K5Y |
| TM4 | 2651 | G | 4.51x51 | CRF1 receptor | 4K5Y | CRF1 receptor | 4K5Y |
| TM4 | 2652 | V | 4.52x52 | CRF1 receptor | 4K5Y | CRF1 receptor | 4K5Y |
| TM4 | 2653 | P | 4.53x53 | CRF1 receptor | 4K5Y | CRF1 receptor | 4K5Y |
| TM4 | 2654 | A | 4.54x54 | CRF1 receptor | 4K5Y | ADGRL3 | 7SF7 |
| TM4 | 2655 | V | 4.55x55 | CRF1 receptor | 4K5Y | CT receptor | 6NIY |
| TM4 | 2656 | L | 4.56x56 | CRF1 receptor | 4K5Y | ADGRG1 | 7SF8 |
| TM4 | 2657 | L | 4.57x57 | CRF1 receptor | 4K5Y | - | - |
| TM4 | 2658 | G | 4.58x58 | CRF1 receptor | 4K5Y | GHRH receptor | 7V9M |
| TM4 | 2659 | L | 4.59x59 | CRF1 receptor | 4K5Y | secretin receptor | 6WZG |
| TM4 | 2660 | A | 4.60x60 | CRF1 receptor | 4K5Y | - | - |
| TM4 | 2661 | V | 4.61x61 | CRF1 receptor | 4K5Y | ADGRG4 | 7WUJ |
| TM4 | 2662 | G | 4.62x62 | CRF1 receptor | 4K5Y | - | - |
| TM4 | 2663 | L | 4.63x63 | CRF1 receptor | 4K5Y | PAC1 receptor | 6P9Y |
| TM4 | 2664 | D | 4.64x64 | CRF1 receptor | 4K5Y | - | - |
| ECL2 | 2665 | P | - | - | - | - | - |
| ECL2 | 2666 | E | - | ADGRD1 | 7WU2 | - | - |
| ECL2 | 2667 | G | - | ADGRD1 | 7WU2 | - | - |
| ECL2 | 2668 | Y | - | ADGRD1 | 7WU2 | ADGRD1 | 7WU2 |
| ECL2 | 2669 | G | - | ADGRD1 | 7WU2 | ADGRD1 | 7WU2 |
| ECL2 | 2670 | N | - | ADGRD1 | 7WU2 | - | - |
| ECL2 | 2671 | P | - | ADGRD1 | 7WU2 | - | - |
| ECL2 | 2672 | D | - | ADGRD1 | 7WU2 | - | - |
| ECL2 | 2673 | F | - | - | - | - | - |
| ECL2 | 2674 | C | 45.50x50 | CRF1 receptor | 4K5Y | CRF1 receptor | 4K5Y |
| ECL2 | 2675 | W | 45.51x51 | CRF1 receptor | 4K5Y | CRF1 receptor | 4K5Y |
| ECL2 | 2676 | I | 45.52x52 | CRF1 receptor | 4K5Y | calcitonin receptor-like receptor | 6UVA |
| ECL2 | 2677 | S | - | - | - | - | - |
| ECL2 | 2678 | V | - | ADGRD1 | 7WU2 | - | - |
| ECL2 | 2679 | H | - | ADGRD1 | 7WU2 | - | - |
| ECL2 | 2680 | E | - | - | - | - | - |
| TM5 | 2681 | P | 5.34x34 | ADGRG4 | 7WUJ | - | - |
| TM5 | 2682 | L | 5.35x35 | ADGRG4 | 7WUJ | - | - |
| TM5 | 2683 | I | 5.36x36 | CRF1 receptor | 4K5Y | ADGRD1 | 7WU2 |
| TM5 | 2684 | W | 5.37x37 | CRF1 receptor | 4K5Y | ADGRD1 | 7WU2 |
| TM5 | 2685 | S | 5.38x38 | ADGRD1 | 7WU2 | ADGRL3 | 7SF7 |
| TM5 | 2686 | F | 5.39x39 | ADGRD1 | 7WU2 | ADGRD1 | 7WU2 |
| TM5 | 2687 | A | 5.40x40 | CRF1 receptor | 4K5Y | - | - |
| TM5 | 2688 | G | 5.41x41 | CRF1 receptor | 4K5Y | CRF1 receptor | 4K5Y |
| TM5 | 2689 | P | 5.42x42 | CRF1 receptor | 4K5Y | CRF1 receptor | 4K5Y |
| TM5 | 2690 | V | 5.43x43 | CRF1 receptor | 4K5Y | secretin receptor | 6WZG |
| TM5 | 2691 | V | 5.44x44 | CRF1 receptor | 4K5Y | PAC1 receptor | 6P9Y |
| TM5 | 2692 | L | 5.45x45 | CRF1 receptor | 4K5Y | CRF1 receptor | 4K5Y |
| TM5 | 2693 | V | 5.46x46 | CRF1 receptor | 4K5Y | CRF1 receptor | 4K5Y |
| TM5 | 2694 | I | 5.47x47 | CRF1 receptor | 4K5Y | ADGRD1 | 7WU2 |
| TM5 | 2695 | V | 5.48x48 | CRF1 receptor | 4K5Y | ADGRD1 | 7WU2 |
| TM5 | 2696 | M | 5.49x49 | CRF1 receptor | 4K5Y | ADGRG4 | 7WUJ |
| TM5 | 2697 | N | 5.50x50 | CRF1 receptor | 4K5Y | CRF1 receptor | 4K5Y |
| TM5 | 2698 | G | 5.51x51 | CRF1 receptor | 4K5Y | - | - |
| TM5 | 2699 | T | 5.52x52 | CRF1 receptor | 4K5Y | - | - |
| TM5 | 2700 | M | 5.53x53 | CRF1 receptor | 4K5Y | ADGRG4 | 7WUJ |
| TM5 | 2701 | F | 5.54x54 | CRF1 receptor | 4K5Y | ADGRG4 | 7WUJ |
| TM5 | 2702 | L | 5.55x55 | CRF1 receptor | 4K5Y | ADGRF1 | 7WU3 |
| TM5 | 2703 | L | 5.56x56 | CRF1 receptor | 4K5Y | ADGRF1 | 7WU3 |
| TM5 | 2704 | A | 5.57x57 | CRF1 receptor | 4K5Y | ADGRL3 | 7SF7 |
| TM5 | 2705 | A | 5.58x58 | CRF1 receptor | 4K5Y | - | - |
| TM5 | 2706 | R | 5.59x59 | CRF1 receptor | 4K5Y | CRF1 receptor | 4K5Y |
| TM5 | 2707 | T | 5.60x60 | CRF1 receptor | 4K5Y | - | - |
| TM5 | 2708 | S | 5.61x61 | CRF1 receptor | 4K5Y | - | - |
| TM5 | 2709 | C | 5.62x62 | CRF1 receptor | 4K5Y | - | - |
| TM5 | 2710 | S | 5.63x63 | CRF1 receptor | 4K5Y | ADGRG4 | 7WUJ |
| TM5 | 2711 | T | 5.64x64 | CRF1 receptor | 4K5Y | - | - |
| TM5 | 2712 | G | 5.65x65 | CRF1 receptor | 4K5Y | - | - |
| TM5 | 2713 | Q | 5.66x66 | ADGRD1 | 7WU2 | PAC1 receptor | 6P9Y |
| TM5 | 2714 | R | 5.67x67 | ADGRD1 | 7WU2 | - | - |
| TM5 | 2715 | E | 5.68x68 | ADGRD1 | 7WU2 | - | - |
| TM5 | 2716 | A | 5.69x69 | ADGRD1 | 7WU2 | - | - |
| TM5 | 2717 | K | 5.70x70 | ADGRD1 | 7WU2 | - | - |
| ICL3 | 2718 | K | - | - | - | - | - |
| TM6 | 2719 | T | 6.34x34 | CRF1 receptor | 4K5Y | ADGRF1 | 7WU3 |
| TM6 | 2720 | S | 6.35x35 | CRF1 receptor | 4K5Y | - | - |
| TM6 | 2721 | A | 6.36x36 | CRF1 receptor | 4K5Y | - | - |
| TM6 | 2722 | L | 6.37x37 | CRF1 receptor | 4K5Y | ADGRD1 | 7WU2 |
| TM6 | 2723 | T | 6.38x38 | CRF1 receptor | 4K5Y | ADGRD1 | 7WU2 |
| TM6 | 2724 | L | 6.39x39 | CRF1 receptor | 4K5Y | ADGRG4 | 7WUJ |
| TM6 | 2725 | R | 6.40x40 | CRF1 receptor | 4K5Y | calcitonin receptor-like receptor | 6UVA |
| TM6 | 2726 | S | 6.41x41 | CRF1 receptor | 4K5Y | ADGRF1 | 7WU3 |
| TM6 | 2727 | S | 6.42x42 | CRF1 receptor | 4K5Y | - | - |
| TM6 | 2728 | F | 6.43x43 | CRF1 receptor | 4K5Y | - | - |
| TM6 | 2729 | L | 6.44x44 | CRF1 receptor | 4K5Y | secretin receptor | 6WZG |
| TM6 | 2730 | L | 6.45x45 | CRF1 receptor | 4K5Y | CRF1 receptor | 4K5Y |
| TM6 | 2731 | L | 6.46x46 | CRF1 receptor | 4K5Y | CRF1 receptor | 4K5Y |
| TM6 | 2732 | L | 6.47x47 | CRF1 receptor | 4K5Y | ADGRG1 | 7SF8 |
| TM6 | 2733 | L | 6.48x48 | CRF1 receptor | 4K5Y | CRF1 receptor | 4K5Y |
| TM6 | 2734 | V | 6.49x49 | CRF1 receptor | 4K5Y | ADGRG3 | 7D77 |
| TM6 | 2735 | S | 6.50x50 | CRF1 receptor | 4K5Y | - | - |
| TM6 | 2736 | A | 6.51x51 | CRF1 receptor | 4K5Y | - | - |
| TM6 | 2737 | S | 6.52x52 | CRF1 receptor | 4K5Y | ADGRD1 | 7WU2 |
| TM6 | 2738 | W | 6.53x53 | CRF1 receptor | 4K5Y | ADGRD1 | 7WU2 |
| TM6 | 2739 | L | 6.54x54 | CRF1 receptor | 4K5Y | - | - |
| TM6 | 2740 | F | 6.55x55 | CRF1 receptor | 4K5Y | ADGRD1 | 7WU2 |
| TM6 | 2741 | G | 6.56x56 | CRF1 receptor | 4K5Y | ADGRD1 | 7WU2 |
| TM6 | 2742 | L | 6.57x57 | CRF1 receptor | 4K5Y | ADGRL3 | 7SF7 |
| TM6 | 2743 | L | 6.58x58 | CRF1 receptor | 4K5Y | - | - |
| TM6 | 2744 | A | 6.59x59 | ADGRD1 | 7WU2 | ADGRD1 | 7WU2 |
| TM6 | 2745 | V | 6.60x60 | ADGRD1 | 7WU2 | ADGRD1 | 7WU2 |
| ECL3 | 2746 | N | - | - | - | - | - |
| ECL3 | 2747 | H | - | - | - | - | - |
| TM7 | 2748 | S | 7.34x33 | CRF1 receptor | 4K5Y | CRF1 receptor | 4K5Y |
| TM7 | 2749 | I | 7.35x34 | CRF1 receptor | 4K5Y | - | - |
| TM7 | 2750 | L | 7.36x35 | CRF1 receptor | 4K5Y | ADGRF1 | 7WU5 |
| TM7 | 2751 | A | 7.37x36 | CRF1 receptor | 4K5Y | ADGRF1 | 7WU3 |
| TM7 | 2752 | F | 7.38x37 | CRF1 receptor | 4K5Y | CRF1 receptor | 4K5Y |
| TM7 | 2753 | H | 7.39x38 | CRF1 receptor | 4K5Y | ADGRF1 | 7WU3 |
| TM7 | 2754 | Y | 7.40x39 | CRF1 receptor | 4K5Y | CRF1 receptor | 4K5Y |
| TM7 | 2755 | L | 7.41x40 | CRF1 receptor | 4K5Y | ADGRL3 | 7SF7 |
| TM7 | 2756 | H | 7.42x41 | CRF1 receptor | 4K5Y | - | - |
| TM7 | 2757 | A | 7.43x42 | CRF1 receptor | 4K5Y | ADGRD1 | 7WU2 |
| TM7 | 2758 | G | 7.44x43 | CRF1 receptor | 4K5Y | PAC1 receptor | 6P9Y |
| TM7 | 2759 | L | 7.45x44 | CRF1 receptor | 4K5Y | CRF1 receptor | 4K5Y |
| TM7 | 2760 | C | 7.46x45 | CRF1 receptor | 4K5Y | - | - |
| TM7 | 2761 | G | 7.47x46 | CRF1 receptor | 4K5Y | - | - |
| TM7 | 2762 | L | 7.48x47 | CRF1 receptor | 4K5Y | ADGRD1 | 7WU2 |
| TM7 | 2763 | Q | 7.49x49 | CRF1 receptor | 4K5Y | CRF1 receptor | 4K5Y |
| TM7 | 2764 | G | 7.50x50 | CRF1 receptor | 4K5Y | CRF1 receptor | 4K5Y |
| TM7 | 2765 | L | 7.51x51 | CRF1 receptor | 4K5Y | ADGRD1 | 7WU2 |
| TM7 | 2766 | A | 7.52x52 | CRF1 receptor | 4K5Y | - | - |
| TM7 | 2767 | V | 7.53x53 | CRF1 receptor | 4K5Y | CRF1 receptor | 4K5Y |
| TM7 | 2768 | L | 7.54x54 | CRF1 receptor | 4K5Y | ADGRF1 | 7WU3 |
| TM7 | 2769 | L | 7.55x55 | CRF1 receptor | 4K5Y | ADGRD1 | 7WU2 |
| TM7 | 2770 | L | 7.56x56 | CRF1 receptor | 4K5Y | secretin receptor | 6WZG |
| TM7 | 2771 | F | 7.57x57 | CRF1 receptor | 4K5Y | calcitonin receptor-like receptor | 6UVA |
| TM7 | 2772 | C | 7.58x58 | CRF1 receptor | 4K5Y | CRF1 receptor | 4K5Y |
| TM7 | 2773 | V | 7.59x59 | CRF1 receptor | 4K5Y | ADGRL3 | 7SF7 |
| TM7 | 2774 | L | 7.60x60 | CRF1 receptor | 4K5Y | CRF1 receptor | 4K5Y |
| H8 | 2775 | N | 8.47x47 | ADGRD1 | 7WU2 | ADGRD1 | 7WU2 |
| H8 | 2776 | A | 8.48x48 | ADGRD1 | 7WU2 | - | - |
| H8 | 2777 | D | 8.49x49 | ADGRD1 | 7WU2 | - | - |
| H8 | 2778 | A | 8.50x50 | ADGRD1 | 7WU2 | - | - |
| H8 | 2779 | R | 8.51x51 | ADGRD1 | 7WU2 | ADGRD1 | 7WU2 |
| H8 | 2780 | A | 8.52x52 | ADGRD1 | 7WU2 | ADGRD1 | 7WU2 |
| H8 | 2781 | A | 8.53x53 | ADGRD1 | 7WU2 | ADGRD1 | 7WU2 |
| H8 | 2782 | W | 8.54x54 | ADGRD1 | 7WU2 | ADGRG4 | 7WUJ |
| H8 | 2783 | M | 8.55x55 | ADGRD1 | 7WU2 | - | - |
| H8 | 2784 | P | 8.56x56 | ADGRD1 | 7WU2 | - | - |
| H8 | 2785 | A | 8.57x57 | ADGRD1 | 7WU2 | - | - |
| H8 | 2786 | C | 8.58x58 | ADGRD1 | 7WU2 | - | - |
| H8 | 2787 | L | 8.59x59 | CRF2 receptor | 6PB1 | - | - |
| H8 | 2788 | G | 8.60x60 | CRF2 receptor | 6PB1 | GHRH receptor | 7CZ5 |
| H8 | 2789 | R | 8.61x61 | CRF2 receptor | 6PB1 | - | - |
| H8 | 2790 | K | 8.62x62 | CRF2 receptor | 6PB1 | CT receptor | 6NIY |
| H8 | 2791 | A | 8.63x63 | CRF2 receptor | 6PB1 | - | - |
| C-term | 2792 | A | - | - | - | - | - |
| C-term | 2793 | P | - | - | - | - | - |
| C-term | 2794 | E | - | - | - | - | - |
| C-term | 2795 | E | - | - | - | - | - |
| C-term | 2796 | A | - | - | - | - | - |