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RECEPTOR EXPRESSION SOLUBILIZATION PURIFICATION STRUCTURE DETERMINATION
PDB pH Temp Resolution Reference Date
5D5A ADRB2 β2 Adrenoceptors A (Rhodopsin) Human BaculovirusSf9Insect 1 chemicals 1 steps in meso/LCPlipidic cubic phase (LCP)monoolein (9.9 MAG) 5 chems 6.5-7.0 20°C Carazolol 2.5 10.1107/S2059798315021683 2016-01-13
5NJ6 PAR2 PAR2 Proteinase-activated A (Rhodopsin) Human BaculovirusSf9Insect 2 chemicals 2 steps in meso/LCPlipidic cubic phase (LCP)monoolein (9.9 MAG) 7 chems 5.5-6.2 20°C FAB3949 + AZ7188 4.0 10.1038/NATURE22309 2017-05-03
2R4S ADRB2 β2 Adrenoceptors A (Rhodopsin) Human BaculovirusSf9Insect 2 chemicals 2 steps vapour diffusionhanging drop 5 chems 6.5-7.5 22°C Carazolol (not resolved) 3.4 10.1038/NATURE06325 2007-11-06
5T1A CCR2 CCR2 Chemokine A (Rhodopsin) Human BaculovirusSf21Insect 4 chemicals 4 steps in meso/LCPlipidic cubic phasemonoolein (9.9 MAG) 5 chems 6.5-6.5 20 °C. BMS-681 2.8 10.1038/NATURE20605 2016-12-14
5XPR EDNRB ETB Endothelin A (Rhodopsin) Human BaculovirusSf9Insect 4 chemicals 4 steps in meso/LCPlipidic cubic phase (LCP)monoolein (9.9 MAG) 5 chems 7.0-7.0 20°C bosentan 3.6 10.1038/NSMB.3450 2017-08-16
5L7I SMO SMO Frizzled F (Frizzled) Human Transient_transfectionHEK293S(TetR)-GnTI-Mammalian 2 chemicals 2 steps in meso/LCPlipidic cubic phase (LCP)monoolein (9.9 MAG) 8 chems 6.0-6.0 20°C Vismodegib 3.3 10.1038/NATURE18934 2016-07-20
3VGA AA2AR A2A Adenosine A (Rhodopsin) Human P.pastorisP. pastoris SMD1163Yeast 2 chemicals 2 steps vapour diffusionhanging drop 4 chems 6.5-6.5 20°C Fab2838 3.1 10.1038/NATURE10750 2012-02-01
6FK9 OPSD Rhodopsin Opsins A (Rhodopsin) Bovine N/A N/A N/A N/A N/A N/A N/A N/A N/A N/A N/A N/A 2.6 10.1073/PNAS.1718084115 2018-04-04
5DHG OPRX NOP Opioid A (Rhodopsin) Human BaculovirusSf9Insect 2 chemicals 2 steps in meso/LCPlipidic cubic phase (LCP)monoolein (9.9 MAG) 5 chems 6.4-6.4 20°C C-35 3.0 10.1016/J.STR.2015.07.024 2015-10-21
5T04 NTR1 NTS1 Neurotensin A (Rhodopsin) Rat BaculovirusTni PRO (Trichoplusia ni) cell linesInsect 2 chemicals 2 steps in meso/LCPlipidic cubic phase (LCP)monoolein (9.9 MAG) 6 chems 8.5-9.0 20°C NTS peptide (8-13) 3.3 10.1038/SREP38564 2016-12-21
5UZ7 CALCR CT Calcitonin B1 (Secretin) Human BaculovirusHi5Insect 2 chemicals 2 steps Cryo-EMVolta phase plate (FEI) 6 chems 7.4-7.4 cryoTemp(liquid Nitrogen) Gs heterotrimeric complex 4.1 10.1038/NATURE22327 2017-05-03
6AQF AA2AR A2A Adenosine A (Rhodopsin) Human 1 chemicals 1 steps 1 chems 0.0-0.0 2.5 10.1016/J.CELL.2017.12.004 2018-01-10
5D6L ADRB2 β2 Adrenoceptors A (Rhodopsin) Human BaculovirusSf9Insect 1 chemicals 1 steps in meso/LCPlipidic cubic phase (LCP)monoolein (9.9 MAG) 5 chems 7.0-7.0 20°C carazolol 3.2 10.1038/NPROT.2017.057 2016-08-17
4XES NTR1 NTS1 Neurotensin A (Rhodopsin) Rat BaculovirusTni PRO (Trichoplusia ni) cell linesInsect 2 chemicals 2 steps in meso/LCPlipidic cubic phase (LCP)monoolein (9.9 MAG) 6 chems 7.0-7.4 20°C NTS 2.6 10.1038/NCOMMS8895 2015-07-29
4PXZ P2Y12 P2Y12 P2Y A (Rhodopsin) Human BaculovirusSf9Insect 6 chemicals 6 steps in meso/LCPlipidic cubic phase (LCP)monoolein (9.9 MAG) 6 chems 5.0-6.0 20°C 2MeSADP 2.5 10.1038/NATURE13288 2014-04-30
5VBL APJ apelin Apelin A (Rhodopsin) Human BaculovirusSf21Insect 4 chemicals 4 steps in meso/LCPlipidic cubic phasemonoolein (9.9 MAG) 7 chems 6.1-6.1 20-22°C AMG3054 2.6 10.1016/J.STR.2017.04.008 2017-05-31
4DKL OPRM μ Opioid A (Rhodopsin) Mouse BaculovirusSf9Insect 12 chemicals 12 steps in meso/LCPlipidic cubic phase (LCP)monoolein (9.9 MAG) 6 chems 7.0-7.0 20°C Morphinan (b-FNA) 2.8 10.1038/NATURE10954 2012-03-21
3AYN OPSD Rhodopsin Opsins A (Rhodopsin) Japanese flying squid NANativeSquid 1 chemicals 1 steps vapour diffusionsitting drop 5 chems 6.0-6.0 4°C 9-cis Retinal 2.7 10.1016/J.JMB.2011.08.044 2011-08-17
5XF1 GLR glucagon Glucagon receptor family B1 (Secretin) Human BaculovirusSf9Insect 4 chemicals 4 steps in meso/LCPlipidic cubic phase (LCP)monoolein (9.9 MAG) 6 chems 7.0-7.0 20°C NNC0640 3.2 10.1038/NATURE22363 2017-05-24
4OR2 GRM1 mGlu1 Metabotropic glutamate C (Glutamate) Human BaculovirusSf9Insect 4 chemicals 4 steps in meso/LCPlipidic cubic phase (LCP)monoolein (9.9 MAG) 6 chems 7.0-7.0 20°C FITM 2.8 10.1126/SCIENCE.1249489 2014-03-19
3V2Y S1PR1 S1P1 Lysophospholipid (S1P) A (Rhodopsin) Human BaculovirusSf9Insect 2 chemicals 2 steps in meso/LCPlipidic cubic phase (LCP)monoolein (9.9 MAG) 5 chems 7.8-7.8 20°C ML056 2.8 10.1126/SCIENCE.1215904 2012-02-15
5X7D ADRB2 β2 Adrenoceptors A (Rhodopsin) Human BaculovirusSf9Insect 3 chemicals 3 steps in meso/LCPlipidic cubic phase (LCP)monoolein (9.9 MAG) 7 chems 7.5-7.5 20°C Cmpd-15PA 2.7 10.1038/NATURE23652 2017-08-16
4RWA OPRD δ Opioid A (Rhodopsin) Human BaculovirusSf9Insect 4 chemicals 4 steps in meso/LCPlipidic cubic phase (LCP)monoolein (9.9 MAG) 6 chems 6.0-6.0 20°C DIPP-NH2 3.3 10.1038/NSMB.2965 2015-01-14
5TVN 5HT2B 5-HT2B 5-Hydroxytryptamine A (Rhodopsin) Human BaculovirusSf21Insect 2 chemicals 2 steps in meso/LCPlipidic cubic phase (LCP)monoolein (9.9 MAG) 5 chems 7.5-8.0 20°C LSD 2.9 10.1016/J.CELL.2016.12.033 2017-02-01
5OLZ AA2AR A2A Adenosine A (Rhodopsin) Human 1 chemicals 1 steps 1 chems 0.0-0.0 Compound 4e (bespoke) 1.9 10.1038/S41598-017-18570-W 2018-01-17
4PHU FFAR1 FFA1 Free fatty acid A (Rhodopsin) Human BaculovirusSf9Insect 6 chemicals 6 steps in meso/LCPlipidic cubic phase (LCP)monoolein (9.9 MAG) 5 chems 7.6-7.6 20°C TAK-875 2.3 10.1038/NATURE13494 2014-07-16
4LDL ADRB2 β2 Adrenoceptors A (Rhodopsin) Human BaculovirusSf9Insect 2 chemicals 2 steps in meso/LCPlipidic cubic phase (LCP)7.7 MAG 5 chems 6.5-6.5 20°C hydroxybenzyl isoproterenol 3.1 10.1038/NATURE12572 2013-09-25
3UON ACM2 M2 Acetylcholine (muscarinic) A (Rhodopsin) Human BaculovirusSf9Insect 2 chemicals 2 steps in meso/LCPlipidic cubic phase (LCP)monoolein (9.9 MAG) 5 chems 7.5-7.5 19.85°C 3-quinuclidinyl-benzilate 3.0 10.1038/NATURE10753 2012-02-01
4XEE NTR1 NTS1 Neurotensin A (Rhodopsin) Rat BaculovirusTni PRO (Trichoplusia ni) cell linesInsect 2 chemicals 2 steps in meso/LCPlipidic cubic phase (LCP)monoolein (9.9 MAG) 6 chems 7.0-8.0 20°C NTS 2.9 10.1038/NCOMMS8895 2015-07-29
4EIY AA2AR A2A Adenosine A (Rhodopsin) Human BaculovirusSf9Insect 2 chemicals 2 steps in meso/LCPlipidic cubic phase (LCP)monoolein (9.9 MAG) 6 chems 5.0-5.0 20°C ZM241385 1.8 10.1126/SCIENCE.1219218 2012-07-25
4QIM SMO SMO Frizzled F (Frizzled) Human BaculovirusSf9Insect 4 chemicals 4 steps in meso/LCPlipidic cubic phasemonoolein (9.9 MAG) 5 chems 7.2-7.2 20°C Anta XV 2.6 10.1038/NCOMMS5355 2014-07-23
2RH1 ADRB2 β2 Adrenoceptors A (Rhodopsin) Human BaculovirusSf9Insect 1 chemicals 1 steps in meso/LCPlipidic cubic phase (LCP)monoolein (9.9 MAG) 5 chems 6.8-6.8 21-23°C Carazolol 2.4 10.1126/SCIENCE.1150577 2007-10-30
3OE0 CXCR4 CXCR4 Chemokine A (Rhodopsin) Human BaculovirusSf9Insect 4 chemicals 4 steps in meso/LCPlipidic cubic phase (LCP)monoolein (9.9 MAG) 5 chems 6.0-6.0 20°C CVX15 peptide 2.9 10.1126/SCIENCE.1194396 2010-10-27
5OLV AA2AR A2A Adenosine A (Rhodopsin) Human 1 chemicals 1 steps 1 chems 0.0-0.0 LUAA47070 (24 hour soak) 2.0 10.1038/S41598-017-18570-W 2018-01-17
5UNG AGTR2 AT2 Angiotensin A (Rhodopsin) Human BaculovirusSf21Insect 4 chemicals 4 steps in meso/LCPlipidic cubic phasemonoolein (9.9 MAG) 7 chems 8.0-8.0 20°C compound 1 (N-benzyl-N-(2-ethyl-4-oxo-3-.. 2.8 10.1038/NATURE22035 2017-04-05
5IUB AA2AR A2A Adenosine A (Rhodopsin) Human BaculovirusTni PRO (Trichoplusia ni) cell linesInsect 1 chemicals 1 steps in meso/LCPlipidic cubic phase (LCP)monoolein (9.9 MAG) 6 chems 5.5-5.5 20°C 12x 2.1 10.1021/ACS.JMEDCHEM.6B00653 2016-06-29
5JTB AA2AR A2A Adenosine A (Rhodopsin) Human BaculovirusSf9Insect 2 chemicals 2 steps in meso/LCPlipidic cubic phase (LCP)monoolein (9.9 MAG) 5 chems 5.0-5.0 20°C ZM241385 2.8 10.1126/SCIADV.1602952 2017-05-31
1HZX OPSD Rhodopsin Opsins A (Rhodopsin) Bovine NANativeBovine 2 chemicals 2 steps vapour diffusionHanging drops 7 chems 6.0-6.0 4°C 11-cis Retinal 2.8 10.1021/BI0155091 2001-07-04
5LWE CCR9 CCR9 Chemokine A (Rhodopsin) Human BaculovirusSf21Insect 1 chemicals 1 steps in meso/LCPlipidic cubic phase (LCP)monoolein (9.9 MAG) 5 chems 7.9-8.0 20°C vercirnon 2.8 10.1038/NATURE20606 2016-12-07
4WW3 OPSD Rhodopsin Opsins A (Rhodopsin) Japanese flying squid NANativeSquid 1 chemicals 1 steps vapour diffusionsitting drop 4 chems 6.4-6.4 100-170 K 11-cis Retinal 2.8 10.1371/JOURNAL.PONE.0126970 2015-06-17
4IB4 5HT2B 5-HT2B 5-Hydroxytryptamine A (Rhodopsin) Human BaculovirusSf9Insect 4 chemicals 4 steps in meso/LCPlipidic cubic phase (LCP)monoolein (9.9 MAG) 7 chems 8.0-8.5 20°C Ergotamine 2.7 10.1126/SCIENCE.1232808 2013-03-13
5L7D SMO SMO Frizzled F (Frizzled) Human Transient_transfectionHEK293S(TetR)-GnTI-Mammalian 2 chemicals 2 steps in meso/LCPlipidic cubic phase (LCP)monoolein (9.9 MAG) 7 chems 4.0-4.0 20°C Ligand-free 3.2 10.1038/NATURE18934 2016-07-20
4LDE ADRB2 β2 Adrenoceptors A (Rhodopsin) Human BaculovirusSf9Insect 2 chemicals 2 steps in meso/LCPlipidic cubic phase (LCP)7.7 MAG 5 chems 6.5-6.5 20°C BI167107 2.8 10.1038/NATURE12572 2013-09-25
4ZUD AGTR1 AT1 Angiotensin A (Rhodopsin) Human BaculovirusSf9Insect 4 chemicals 4 steps in meso/LCPlipidic cubic phase (LCP)monoolein (9.9 MAG) 6 chems 5.0-5.0 20°C Olmesartan 2.8 10.1074/JBC.M115.689000 2015-10-07
2R4R ADRB2 β2 Adrenoceptors A (Rhodopsin) Human BaculovirusSf9Insect 2 chemicals 2 steps vapour diffusionhanging drop 5 chems 6.5-7.5 22°C Carazolol (not resolved) 3.4 10.1038/NATURE06325 2007-11-06
3EML AA2AR A2A Adenosine A (Rhodopsin) Human BaculovirusSf9Insect 4 chemicals 4 steps in meso/LCPlipidic cubic phase (LCP)monoolein (9.9 MAG) 5 chems 6.5-6.5 20°C ZM241385 2.6 10.1126/SCIENCE.1164772 2008-10-14
3RFM AA2AR A2A Adenosine A (Rhodopsin) Human BaculovirusSf9Insect 1 chemicals 1 steps vapour diffusionsitting drop 6 chems 8.0-8.8 4°C Caffeine 3.6 10.1016/J.STR.2011.06.014 2011-09-07
5GLI EDNRB ETB Endothelin A (Rhodopsin) Human BaculovirusSf9Insect 6 chemicals 6 steps in meso/LCPlipidic cubic phase (LCP)monoolein (9.9 MAG) 6 chems 6.3-6.3 20°C Ligand free 2.5 10.1038/NATURE19319 2016-09-07
2YCY ADRB1 β1 Adrenoceptors A (Rhodopsin) Common turkey BaculovirusHi5Insect 2 chemicals 2 steps vapour diffusionNA 3 chems 6.9-7.3 NA Cyanopindolol 3.2 10.1073/PNAS.1100185108 2011-06-08
5XRA CNR1 CB1 Cannabinoid A (Rhodopsin) Human Transient_transfectionHEK293TMammalian 4 chemicals 4 steps in meso/LCPlipidic cubic phase (LCP)monoolein (9.9 MAG) 5 chems 6.4-6.4 20°C AM11542 2.8 10.1038/NATURE23272 2017-07-12
2J4Y OPSD Rhodopsin Opsins A (Rhodopsin) Bovine Transient_transfectionCOS1Mammalian 1 chemicals 1 steps vapour diffusionsitting drops 3 chems 7.5-7.5 4°C 11-cis Retinal 3.4 10.1016/J.JMB.2007.03.007 2007-09-25
4AMI ADRB1 β1 Adrenoceptors A (Rhodopsin) Common turkey BaculovirusHi5Insect 2 chemicals 2 steps vapour diffusionsitting drops 3 chems 9.0-9.0 4°C Bucindolol 3.2 10.1016/J.STR.2012.03.014 2012-05-23
5X33 Q9WTK1 BLT1 Leukotriene A (Rhodopsin) Guinea pig Pichia PastorisP. pastoris SMD1163Yeast 4 chemicals 4 steps in meso/LCPlipidic cubic phasemonoolein (9.9 MAG) 7 chems 8.5-9.0 4°C BIIL260 3.7 10.1038/NCHEMBIO.2547 2018-01-03
5VAI G1SGD4 GLP-1 Glucagon receptor family B1 (Secretin) Rabbit BaculovirusSf9Insect 6 chemicals 6 steps Cryo-EMFEI, glow-discharged holey carbon grids 7 chems 7.5-7.5 20°C GLP-1 4.1 10.1038/NATURE22394 2017-05-24
5XSZ Q08BG4 LPA6 Lysophospholipid (LPA) A (Rhodopsin) Zebrafish BaculovirusSf9Insect 8 chemicals 8 steps in meso/LCPlipidic cubic phasemonoolein (9.9 MAG) 6 chems 6.0-6.0 20°C monoolein 3.2 10.1038/NATURE23448 2017-08-16
2VT4 ADRB1 β1 Adrenoceptors A (Rhodopsin) Common turkey BaculovirusHi5Insect 2 chemicals 2 steps vapour diffusionhanging drop 4 chems 6.9-7.3 18°C Cyanopindolol 2.7 10.1038/NATURE07101 2008-06-24
6FKA OPSD Rhodopsin Opsins A (Rhodopsin) Bovine N/A N/A N/A N/A N/A N/A N/A N/A N/A N/A N/A N/A 2.7 10.1073/PNAS.1718084115 2018-04-04
5IU8 AA2AR A2A Adenosine A (Rhodopsin) Human BaculovirusTni PRO (Trichoplusia ni) cell linesInsect 1 chemicals 1 steps in meso/LCPlipidic cubic phase (LCP)monoolein (9.9 MAG) 6 chems 5.5-5.5 20°C 12f 2.0 2016-06-29
4DJH OPRK κ Opioid A (Rhodopsin) Human BaculovirusSf9Insect 4 chemicals 4 steps in meso/LCPlipidic cubic phase (LCP)monoolein (9.9 MAG) 5 chems 6.0-6.0 20°C JDTic 2.9 10.1038/NATURE10939 2012-03-21
4N6H OPRD δ Opioid A (Rhodopsin) Human BaculovirusSf9Insect 4 chemicals 4 steps in meso/LCPlipidic cubic phase (LCP)monoolein (9.9 MAG) 7 chems 6.1-6.2 20-23°C Naltrindole 1.8 10.1038/NATURE12944 2013-12-25
6CM4 DRD2 D2 Dopamine A (Rhodopsin) Human BaculovirusSf9Insect 4 chemicals 4 steps in meso/LCPlipidic cubic phasemonoolein (9.9 MAG) 6 chems 7.8-7.8 20°C Risperidone 2.9 10.1038/NATURE25758 2018-03-14
4XNW P2RY1 P2Y1 P2Y A (Rhodopsin) Human BaculovirusSf9Insect 6 chemicals 6 steps in meso/LCPlipidic cubic phase (LCP)monoolein (9.9 MAG) 5 chems 7.0-8.0 20°C MRS2500 2.7 10.1038/NATURE14287 2015-04-01
3KJ6 ADRB2 β2 Adrenoceptors A (Rhodopsin) Human BaculovirusSf9Insect 3 chemicals 3 steps vapour diffusionbicelles 5 chems 7.5-7.5 298K Carazolol (not resolved) 3.4 10.1038/NATURE08650 2010-02-16
4XT1 US28 US28 Unclassified A (Rhodopsin) strain AD169 BaculovirusHEK293S(TetR)-GnTI-Mammalian 2 chemicals 2 steps in meso/LCPlipidic cubic phase (LCP)monoolein (9.9 MAG) 7 chems 6.3-7.0 20°C CX3CL1 with Nb7 2.9 10.1126/SCIENCE.AAA5026 2015-03-04
2HPY OPSD Rhodopsin Opsins A (Rhodopsin) Bovine NANativeBovine 1 chemicals 1 steps vapour diffusionHanging drops 5 chems 5.9-6.1 283 K all trans retinal 2.8 10.1073/PNAS.0601765103 2006-08-22
5W0P OPSD Rhodopsin Opsins A (Rhodopsin) Human Transient_transfectionHEK293S(TetR- GnTI-Mammalian 2 chemicals 2 steps in meso/LCPlipidic cubic phase (LCP)monopalmitolein (9.7 MAG) 5 chems 5.0-5.0 20°C all trans retinal 3.0 10.1016/J.CELL.2017.07.002 2017-08-09
3ZEV NTR1 NTS1 Neurotensin A (Rhodopsin) Rat NAE. coli BL21(DE3)Bacteria 3 chemicals 3 steps vapour diffusionsitting drops 7 chems 9.4-9.4 4°C NT1 (neurotensin) 3.0 10.1073/PNAS.1317903111 2014-01-29
5N2R AA2AR A2A Adenosine A (Rhodopsin) Human BaculovirusTni PRO (Trichoplusia ni) cell linesInsect 1 chemicals 1 steps in meso/LCPlipidic cubic phase (LCP)monoolein (9.9 MAG) 5 chems 5.3-5.4 20 PSB36 2.8 10.1016/J.STR.2017.06.012 2017-07-26
2YDO AA2AR A2A Adenosine A (Rhodopsin) Human BaculovirusHi5Insect 4 chemicals 4 steps vapour diffusionsitting drop 5 chems 7.6-7.6 4°C Adenosine 3.0 10.1038/NATURE10136 2011-05-18
4IAR 5HT1B 5-HT1B 5-Hydroxytryptamine A (Rhodopsin) Human BaculovirusSf9Insect 4 chemicals 4 steps in meso/LCPlipidic cubic phase (LCP)monoolein (9.9 MAG) 5 chems 7.5-7.5 20°C Ergotamine 2.7 10.1126/SCIENCE.1232807 2013-03-13
5OLO AA2AR A2A Adenosine A (Rhodopsin) Human 1 chemicals 1 steps 1 chems 0.0-0.0 Tozadenant (24 hours soak) 3.1 10.1038/S41598-017-18570-W 2018-01-17
3PDS ADRB2 β2 Adrenoceptors A (Rhodopsin) Human BaculovirusSf9Insect 3 chemicals 3 steps in meso/LCPlipidic cubic phase (LCP)monoolein (9.9 MAG) 6 chems 6.7-6.7 20°C FAUC50 3.5 10.1038/NATURE09665 2011-01-12
3NY9 ADRB2 β2 Adrenoceptors A (Rhodopsin) Human BaculovirusSf9Insect 2 chemicals 2 steps in meso/LCPlipidic cubic phase (LCP)monoolein (9.9 MAG) 6 chems 7.5-8.0 20°C Compound 1 (ethyl 4-[2-hydroxy-3-(isop.. 2.8 10.1021/JA105108Q 2010-08-11
2YCW ADRB1 β1 Adrenoceptors A (Rhodopsin) Common turkey BaculovirusHi5Insect 2 chemicals 2 steps vapour diffusionNA 3 chems 8.1-8.1 NA Carazolol 3.0 10.1073/PNAS.1100185108 2011-06-01
3NY8 ADRB2 β2 Adrenoceptors A (Rhodopsin) Human BaculovirusSf9Insect 2 chemicals 2 steps in meso/LCPlipidic cubic phase (LCP)monoolein (9.9 MAG) 6 chems 7.5-8.0 20°C ICI118551 2.8 10.1021/JA105108Q 2010-08-11
3OE9 CXCR4 CXCR4 Chemokine A (Rhodopsin) Human BaculovirusSf9Insect 4 chemicals 4 steps in meso/LCPlipidic cubic phase (LCP)monoolein (9.9 MAG) 6 chems 6.0-6.0 20°C IT1t 3.1 10.1126/SCIENCE.1194396 2010-10-27
4S0V OX2R OX2 Orexin A (Rhodopsin) Human BaculovirusSf9Insect 9 chemicals 9 steps in meso/LCPlipidic cubic phase (LCP)monoolein (9.9 MAG) 5 chems 5.9-6.0 20°C Suvorexant 2.5 10.1038/NATURE14035 2015-01-14
5DYS OPSD Rhodopsin Opsins A (Rhodopsin) Bovine Stable_cellsHEK293S-GnTI-Mammalian 1 chemicals 1 steps vapour diffusionSitting drop 4 chems 4.5-4.5 20°C all-trans Retinal 2.3 10.15252/EMBR.201642671 2016-08-10
4Z36 LPAR1 LPA1 Lysophospholipid (LPA) A (Rhodopsin) Human BaculovirusSf9Insect 2 chemicals 2 steps in meso/LCPlipidic cubic phase (LCP)monoolein (9.9 MAG) 5 chems 5.5-5.5 20°C ONO-3080573 2.9 10.1016/J.CELL.2015.06.002 2015-06-03
2X72 OPSD Rhodopsin Opsins A (Rhodopsin) Bovine Stable_cellsHEK293S-GnTI-Mammalian 1 chemicals 1 steps vapour diffusionsitting drop 3 chems 4.5-4.5 4°C all-trans retinal 3.0 10.1038/NATURE09795 2011-03-16
5JQH ADRB2 β2 Adrenoceptors A (Rhodopsin) Human BaculovirusSf9Insect 1 chemicals 1 steps in meso/LCPlipidic cubic phase (LCP)7.7 MAG 5 chems 7.5-7.5 23°C Carazolol 3.2 10.1038/NATURE18636 2016-07-13
5IU4 AA2AR A2A Adenosine A (Rhodopsin) Human BaculovirusTni PRO (Trichoplusia ni) cell linesInsect 1 chemicals 1 steps in meso/LCPlipidic cubic phase (LCP)monoolein (9.9 MAG) 6 chems 5.5-5.5 20 ZM241385 1.7 10.1021/ACS.JMEDCHEM.6B00653 2016-06-29
4U14 ACM3 M3 Acetylcholine (muscarinic) A (Rhodopsin) Rat BaculovirusSf9Insect 9 chemicals 9 steps sponge mesophaselipidic cubic phase (LCP)monoolein (9.9 MAG) 6 chems 8.1-8.1 298 K Tiotropium 3.6 10.1016/J.STR.2014.08.022 2014-11-26
4BV0 NTR1 NTS1 Neurotensin A (Rhodopsin) Rat NAE. coli BL21(DE3)Bacteria 3 chemicals 3 steps vapour diffusionsitting drops 5 chems 9.4-9.4 4°C NT1 (neurotensin) 3.1 10.1073/PNAS.1317903111 2014-01-29
5UEN AA1R A1 Adenosine A (Rhodopsin) Human BaculovirusSf9Insect 6 chemicals 6 steps in meso/LCPlipidic cubic phase (LCP)monoolein (9.9 MAG) 5 chems 7.0-8.0 20°C DU172 3.2 10.1016/J.CELL.2017.01.042 2017-03-01
5MZJ AA2AR A2A Adenosine A (Rhodopsin) Human BaculovirusTni PRO (Trichoplusia ni) cell linesInsect 1 chemicals 1 steps in meso/LCPlipidic cubic phase (LCP)monoolein (9.9 MAG) 5 chems 5.3-5.4 20 12b 2.0 10.1016/J.STR.2017.06.012 2017-07-26
2I36 OPSD Rhodopsin Opsins A (Rhodopsin) Bovine NANativeBovine 2 chemicals 2 steps vapour diffusionsitting drops 5 chems 7.0-8.0 5°C All-trans retinal 4.1 10.1073/PNAS.0608022103 2006-10-17
3PQR OPSD Rhodopsin Opsins A (Rhodopsin) Bovine NANativeBovine 1 chemicals 1 steps vapour diffusionHanging drops 3 chems 5.6-5.6 4°C All-trans retinal 2.9 10.1038/NATURE09789 2011-03-09
4BEZ OPSD Rhodopsin Opsins A (Rhodopsin) Bovine Stable_cellsHEK293S-GnTI-Mammalian 1 chemicals 1 steps vapour diffusionsitting drop 4 chems 4.5-4.5 20°C all-trans retinal 3.3 10.1038/EMBOR.2013.44 2013-04-24
5A8E ADRB1 β1 Adrenoceptors A (Rhodopsin) Common turkey BaculovirusHi5Insect 1 chemicals 1 steps in meso/LCPlipidic cubic phase (LCP)monoolein (9.9 MAG) 4 chems 7.0-7.0 20°C 7-methylcyanopindolol 2.4 10.1124/MOL.115.101030 2015-09-30
5UIW CCR5 CCR5 Chemokine A (Rhodopsin) Human BaculovirusSf21Insect 4 chemicals 4 steps in meso/LCPlipidic cubic phase (LCP)monoolein (9.9 MAG) 6 chems 6.3-6.3 20°C chemokine 5P7-CCL5 2.2 10.1016/J.IMMUNI.2017.05.002 2017-06-28
3UZA AA2AR A2A Adenosine A (Rhodopsin) Human BaculovirusSf9Insect 1 chemicals 1 steps vapour diffusionsitting drop 6 chems 8.0-8.0 4°C T4G (6-(2,6-Dimethylpyridin-4-yl)-5-phen.. 3.3 10.1021/JM201376W 2012-03-21
4OO9 GRM5 mGlu5 Metabotropic glutamate C (Glutamate) Human BaculovirusSf21Insect 1 chemicals 1 steps in meso/LCPlipidic cubic phase (LCP)monoolein (9.9 MAG) 4 chems 6.8-6.8 20°C mavoglurant 2.6 10.1038/NATURE13396 2014-07-02
5WF5 AA2AR A2A Adenosine A (Rhodopsin) Human 1 chemicals 1 steps 1 chems 0.0-0.0 2.6 10.1016/J.STR.2017.12.013 2018-02-21
5K2B AA2AR A2A Adenosine A (Rhodopsin) Human BaculovirusSf9Insect 2 chemicals 2 steps in meso/LCPlipidic cubic phase (LCP)monoolein (9.9 MAG) 5 chems 5.0-5.0 20°C ZM241385 2.5 10.1126/SCIADV.1600292 2016-09-21
5V56 SMO SMO Frizzled F (Frizzled) Human 1 chemicals 1 steps 1 chems 0.0-0.0 2.9 10.1038/NCOMMS15383 2017-05-24
4U15 ACM3 M3 Acetylcholine (muscarinic) A (Rhodopsin) Rat BaculovirusSf9Insect 9 chemicals 9 steps in meso/LCPlipidic cubic phase (LCP)monoolein (9.9 MAG) 5 chems 7.5-7.5 298 K Tiotropium 2.8 10.1016/J.STR.2014.08.022 2014-11-26
4BWB NTR1 NTS1 Neurotensin A (Rhodopsin) Rat NAE. coli BL21(DE3)Bacteria 3 chemicals 3 steps vapour diffusionsitting drops 7 chems 5.5-5.5 4°C NT1 (neurotensin) 3.6 10.1073/PNAS.1317903111 2014-01-29
1GZM OPSD Rhodopsin Opsins A (Rhodopsin) Bovine NANativeBovine 1 chemicals 1 steps vapour diffusionsitting drops 3 chems 8.5-8.5 18°C 11-cis Retinal 2.7 10.1016/J.JMB.2004.08.090 2003-11-20
3QAK AA2AR A2A Adenosine A (Rhodopsin) Human BaculovirusSf9Insect 2 chemicals 2 steps in meso/LCPlipidic cubic phase (LCP)monoolein (9.9 MAG) 5 chems 5.0-5.5 20°C UK-432097 2.7 10.1126/SCIENCE.1202793 2011-03-09
4Z35 LPAR1 LPA1 Lysophospholipid (LPA) A (Rhodopsin) Human BaculovirusSf9Insect 2 chemicals 2 steps in meso/LCPlipidic cubic phase (LCP)monoolein (9.9 MAG) 5 chems 5.5-5.5 20°C ONO-9910539 2.9 10.1016/J.CELL.2015.06.002 2015-06-03
5NLX AA2AR A2A Adenosine A (Rhodopsin) Human BaculovirusSf9Insect 1 chemicals 1 steps in meso/LCPlipidic cubic phasemonoolein (9.9 MAG) 5 chems 5.0-5.0 20°C ZM241385 2.1 10.1038/S41467-017-00630-4 2017-09-27
5NM4 AA2AR A2A Adenosine A (Rhodopsin) Human BaculovirusSf9Insect 1 chemicals 1 steps in meso/LCPlipidic cubic phasemonoolein (9.9 MAG) 5 chems 5.0-5.0 20°C ZM241385 1.7 10.1038/S41467-017-00630-4 2017-09-27
5EE7 GLR glucagon Glucagon receptor family B1 (Secretin) Human Transient_transfectionSf21Insect 1 chemicals 1 steps in meso/LCPlipidic cubic phase (LCP)monoolein (9.9 MAG) 4 chems 5.5-6.5 20°C MK-0893 2.5 10.1038/NATURE17414 2016-04-20
5N2S AA1R A1 Adenosine A (Rhodopsin) Human BaculovirusTni PRO (Trichoplusia ni) cell linesInsect 1 chemicals 1 steps in meso/LCPlipidic cubic phase (LCP)monoolein (9.9 MAG) 4 chems 7.5-7.5 20°C PSB36 3.3 10.1016/J.STR.2017.06.012 2017-07-26
5OM1 AA2AR A2A Adenosine A (Rhodopsin) Human 1 chemicals 1 steps 1 chems 0.0-0.0 Compound 4e (1 hour soak) 2.1 10.1038/S41598-017-18570-W 2018-01-17
6FKB OPSD Rhodopsin Opsins A (Rhodopsin) Bovine N/A N/A N/A N/A N/A N/A N/A N/A N/A N/A N/A N/A 3.0 10.1073/PNAS.1718084115 2018-04-04
4PXF OPSD Rhodopsin Opsins A (Rhodopsin) Bovine NANativeBovine 1 chemicals 1 steps vapour diffusionsitting drop 3 chems 6.0-6.0 4°C beta-OG binding partner 2.8 10.1038/NCOMMS5801 2014-09-17
6FFI GRM5 mGlu5 Metabotropic glutamate C (Glutamate) Human 1 chemicals 1 steps 1 chems 0.0-0.0 2.2 10.1021/ACS.JMEDCHEM.7B01722 2018-03-07
6FFH GRM5 mGlu5 Metabotropic glutamate C (Glutamate) Human 1 chemicals 1 steps 1 chems 0.0-0.0 2.7 10.1021/ACS.JMEDCHEM.7B01722 2018-03-07
2Y00 ADRB1 β1 Adrenoceptors A (Rhodopsin) Common turkey BaculovirusHi5Insect 1 chemicals 1 steps vapour diffusionsitting drops 6 chems 8.5-8.5 4°C DOBUTAMINE 2.5 10.1038/NATURE09746 2011-01-12
5YQZ GLR glucagon Glucagon receptor family B1 (Secretin) Human 1 chemicals 1 steps 1 chems 0.0-0.0 3.0 10.1038/NATURE25153 2018-01-17
4BUO NTR1 NTS1 Neurotensin A (Rhodopsin) Rat NAE. coli BL21(DE3)Bacteria 6 chemicals 6 steps vapour diffusionSitting drop 5 chems 9.4-9.4 4°C NT1 (neurotensin) 2.8 10.1073/PNAS.1317903111 2014-01-29
5WIU DRD4 D4 Dopamine A (Rhodopsin) Human BaculovirusSf9Insect 4 chemicals 4 steps in meso/LCPlipidic cubic phasemonoolein (9.9 MAG) 5 chems 5.8-6.2 20°C Nemonapride 2.0 10.1126/SCIENCE.AAN5468 2017-10-18
4GBR ADRB2 β2 Adrenoceptors A (Rhodopsin) Human BaculovirusSf9Insect 1 chemicals 1 steps in meso/LCPlipidic cubic phase (LCP)monoolein (9.9 MAG) 4 chems 6.5-6.5 20°C Carazolol 4.0 10.1371/JOURNAL.PONE.0046039 2012-10-24
5K2C AA2AR A2A Adenosine A (Rhodopsin) Human BaculovirusSf9Insect 2 chemicals 2 steps in meso/LCPlipidic cubic phase (LCP)monoolein (9.9 MAG) 5 chems 5.0-5.0 20°C ZM241385 1.9 10.1126/SCIADV.1600292 2016-09-21
4QIN SMO SMO Frizzled F (Frizzled) Human BaculovirusSf9Insect 4 chemicals 4 steps in meso/LCPlipidic cubic phasemonoolein (9.9 MAG) 6 chems 7.2-7.2 20°C SAG1.5 2.6 10.1038/NCOMMS5355 2014-07-23
4MBS CCR5 CCR5 Chemokine A (Rhodopsin) Human BaculovirusSf9Insect 4 chemicals 4 steps in meso/LCPlipidic cubic phase (LCP)monoolein (9.9 MAG) 5 chems 7.0-7.0 20°C HIV drug Maraviroc 2.7 10.1126/SCIENCE.1241475 2013-09-11
5TUD 5HT2B 5-HT2B 5-Hydroxytryptamine A (Rhodopsin) Human BaculovirusSf21Insect 2 chemicals 2 steps in meso/LCPlipidic cubic phase (LCP)monopalmitolein (9.7 MAG) 6 chems 7.7-7.7 20°C Ergotamine 3.0 10.1073/PNAS.1700891114 2017-07-26
2Y01 ADRB1 β1 Adrenoceptors A (Rhodopsin) Common turkey BaculovirusHi5Insect 1 chemicals 1 steps vapour diffusionsitting drops 6 chems 9.0-9.0 4°C Dobutamine 2.6 10.1038/NATURE09746 2011-03-30
4Z9G CRFR1 CRF1 Corticotropin-releasing factor B1 (Secretin) Human BaculovirusHi5Insect 1 chemicals 1 steps in meso/LCPlipidic cubic phase (LCP)monoolein (9.9 MAG) 4 chems 5.5-5.5 23°C CP-376395 3.2 10.2174/1874467210666170110114727 2016-06-29
2YCZ ADRB1 β1 Adrenoceptors A (Rhodopsin) Common turkey BaculovirusHi5Insect 2 chemicals 2 steps vapour diffusionNA 3 chems 6.9-7.3 NA Iodocyanopindolol 3.7 10.1073/PNAS.1100185108 2011-06-01
4EA3 OPRX NOP Opioid A (Rhodopsin) Human BaculovirusSf9Insect 2 chemicals 2 steps in meso/LCPlipidic cubic phase (LCP)monoolein (9.9 MAG) 5 chems 6.4-6.4 20°C peptide mimetic coumpound-24 3.0 10.1038/NATURE11085 2012-04-25
4NC3 5HT2B 5-HT2B 5-Hydroxytryptamine A (Rhodopsin) Human BaculovirusSf9Insect 2 chemicals 2 steps in meso/LCPlipidic cubic phase (LCP)monoolein (9.9 MAG) 5 chems 8.0-8.0 20°C Ergotamine 2.8 10.1126/SCIENCE.1244142 2013-12-18
5WKT OPSD Rhodopsin Opsins A (Rhodopsin) Bovine NANativeBovine 1 chemicals 1 steps vapour diffusionHanging drop 4 chems 5.5-5.5 7-10°C Ga peptide 3.2 10.1038/NPROT.2017.135 2017-12-13
4LDO ADRB2 β2 Adrenoceptors A (Rhodopsin) Human BaculovirusSf9Insect 2 chemicals 2 steps in meso/LCPlipidic cubic phase (LCP)7.7 MAG 5 chems 6.5-6.5 20°C Adrenaline 3.2 10.1038/NATURE12572 2013-09-25
2Y03 ADRB1 β1 Adrenoceptors A (Rhodopsin) Common turkey BaculovirusHi5Insect 1 chemicals 1 steps vapour diffusionsitting drops 6 chems 8.5-8.5 4°C Isoprenaline 2.9 10.1038/NATURE09746 2011-01-12
5F8U ADRB1 β1 Adrenoceptors A (Rhodopsin) Common turkey BaculovirusHi5Insect 1 chemicals 1 steps vapour diffusionHanging drops 1 chems 3.6-4.0 18°C Cyanopindolol 3.4 10.1038/NSMB.3130 2015-12-23
1U19 OPSD Rhodopsin Opsins A (Rhodopsin) Bovine NANativeBovine 1 chemicals 1 steps vapour diffusionHanging drops 5 chems 6.5-7.5 283 K 11-cis Retinal 2.2 10.1016/J.JMB.2004.07.044 2004-10-12
3OAX OPSD Rhodopsin Opsins A (Rhodopsin) Bovine NANativeBovine 1 chemicals 1 steps vapour diffusionHanging drops 5 chems 6.0-6.0 283 K Beta-ionone 2.6 10.1016/J.BPJ.2010.08.003 2011-01-19
4N4W SMO SMO Frizzled F (Frizzled) Human BaculovirusSf9Insect 4 chemicals 4 steps in meso/LCPlipidic cubic phasemonoolein (9.9 MAG) 7 chems 6.9-6.9 20°C SANT-1 2.8 10.1038/NCOMMS5355 2014-01-22
3PBL DRD3 D3 Dopamine A (Rhodopsin) Human BaculovirusSf9Insect 6 chemicals 6 steps in meso/LCPlipidic cubic phase (LCP)monoolein (9.9 MAG) 6 chems 7.5-7.5 20°C Eticlopride 2.9 10.1126/SCIENCE.1197410 2010-11-03
5G53 AA2AR A2A Adenosine A (Rhodopsin) Human BaculovirusTni PRO (Trichoplusia ni) cell linesInsect 1 chemicals 1 steps vapour diffusionSitting drop 6 chems 5.7-5.7 4°C Ligand free but with engineered G-protei.. 3.4 10.1038/NATURE18966 2016-08-03
4XNV P2RY1 P2Y1 P2Y A (Rhodopsin) Human BaculovirusSf9Insect 6 chemicals 6 steps in meso/LCPlipidic cubic phase (LCP)monoolein (9.9 MAG) 5 chems 6.5-6.5 20°C BPTU -- BMS compound 16 synonym 2.2 10.1038/NATURE14287 2015-04-01
4NTJ P2Y12 P2Y12 P2Y A (Rhodopsin) Human BaculovirusSf9Insect 6 chemicals 6 steps in meso/LCPlipidic cubic phase (LCP)monoolein (9.9 MAG) 5 chems 6.0-6.5 20°C AZD1283 2.6 10.1038/NATURE13083 2014-03-26
4XT3 US28 US28 Unclassified A (Rhodopsin) strain AD169 BaculovirusHEK293S(TetR)-GnTI-Mammalian 2 chemicals 2 steps in meso/LCPlipidic cubic phase (LCP)monovaccenin(11.7 MAG) 6 chems 7.4-7.4 20°C CX3CL1 3.8 10.1126/SCIENCE.AAA5026 2015-03-04
5C1M OPRM μ Opioid A (Rhodopsin) Mouse BaculovirusSf9Insect 6 chemicals 6 steps in meso/LCPlipidic cubic phase (LCP)monoolein (9.9 MAG) 7 chems 7.5-7.5 20°C BU72 (synonym 4VO) 2.1 10.1038/NATURE14886 2015-08-05
5NDZ PAR2 PAR2 Proteinase-activated A (Rhodopsin) Human BaculovirusSf9Insect 2 chemicals 2 steps in meso/LCPlipidic cubic phase (LCP)monoolein (9.9 MAG) 6 chems 5.5-6.2 20°C AZ3451 (formulae : (S)-2-(6-bromobenzo[d.. 3.6 10.1038/NATURE22309 2017-05-03
5WIV DRD4 D4 Dopamine A (Rhodopsin) Human BaculovirusSf9Insect 4 chemicals 4 steps in meso/LCPlipidic cubic phase (LCP)monoolein (9.9 MAG) 6 chems 5.9-6.2 20°C Nemonapride 2.1 10.1126/SCIENCE.AAN5468 2017-10-18
5OLG AA2AR A2A Adenosine A (Rhodopsin) Human 1 chemicals 1 steps 1 chems 0.0-0.0 ZM241385 (24 hour soak) 1.9 10.1038/S41598-017-18570-W 2018-01-17
4X1H OPSD Rhodopsin Opsins A (Rhodopsin) Bovine NANativeBovine 1 chemicals 1 steps vapour diffusionsitting drop 3 chems 5.0-6.5 4°C transducin analoguepeptide (VLEDLKSCGLF).. 2.3 10.1016/J.STR.2015.09.015 2015-11-04
3VG9 AA2AR A2A Adenosine A (Rhodopsin) Human P.pastorisP. pastoris SMD1163Yeast 2 chemicals 2 steps vapour diffusionhanging drop 4 chems 6.5-6.5 20°C Fab2838 2.7 10.1038/NATURE10750 2012-02-01
4RWD OPRD δ Opioid A (Rhodopsin) Human BaculovirusSf9Insect 4 chemicals 4 steps in meso/LCPlipidic cubic phase (LCP)monoolein (9.9 MAG) 5 chems 6.0-6.0 20°C DIPP-NH2 2.7 10.1038/NSMB.2965 2015-01-14
5VEW GLP1R GLP-1 Glucagon receptor family B1 (Secretin) Human BaculovirusSf9Insect 2 chemicals 2 steps in meso/LCPlipidic cubic phase (LCP)monoolein (9.9 MAG) 6 chems 6.2-6.6 20°C PF-06372222 2.7 10.1038/NATURE22378 2017-05-24
5EN0 OPSD Rhodopsin Opsins A (Rhodopsin) Bovine Stable_cellsHEK293S(TetR)GnTI-Mammalian 1 chemicals 1 steps vapour diffusionSitting drop 4 chems 5.0-5.0 4°C GaCT2 peptide 2.8 10.15252/EMBR.201642671 2016-08-10
5CGD GRM5 mGlu5 Metabotropic glutamate C (Glutamate) Human BaculovirusSf21Insect 1 chemicals 1 steps in meso/LCPlipidic cubic phase (LCP)monoolein (9.9 MAG) 4 chems 5.5-6.8 20°C Compound 25 2.6 10.1021/ACS.JMEDCHEM.5B00892 2015-08-12
4MQS ACM2 M2 Acetylcholine (muscarinic) A (Rhodopsin) Human BaculovirusSf9Insect 2 chemicals 2 steps in meso/LCPlipidic cubic phase (LCP)monoolein (9.9 MAG) 6 chems 7.2-7.9 20°C Iperoxo & Nb9-8 3.5 10.1038/NATURE12735 2013-11-27
5NX2 GLP1R GLP-1 Glucagon receptor family B1 (Secretin) Human BaculovirusSf9Insect 2 chemicals 2 steps vapour diffusionSitting drop 4 chems 8.0-9.0 10°C GLP-1 truncated 3.7 10.1038/NATURE22800 2017-06-14
3OE8 CXCR4 CXCR4 Chemokine A (Rhodopsin) Human BaculovirusSf9Insect 4 chemicals 4 steps in meso/LCPlipidic cubic phase (LCP)monoolein (9.9 MAG) 6 chems 6.0-6.0 20°C IT1t 3.1 10.1126/SCIENCE.1194396 2010-10-27
5MZP AA2AR A2A Adenosine A (Rhodopsin) Human BaculovirusTni PRO (Trichoplusia ni) cell linesInsect 1 chemicals 1 steps in meso/LCPlipidic cubic phase (LCP)monoolein (9.9 MAG) 5 chems 5.3-5.4 20 12b 2.1 10.1016/J.STR.2017.06.012 2017-07-26
5V54 5HT1B 5-HT1B 5-Hydroxytryptamine A (Rhodopsin) Human 1 chemicals 1 steps 1 chems 0.0-0.0 3.9 2018-02-07
3D4S ADRB2 β2 Adrenoceptors A (Rhodopsin) Human BaculovirusSf9Insect 2 chemicals 2 steps in meso/LCPlipidic cubic phase (LCP)monoolein (9.9 MAG) 5 chems 7.0-7.0 20°C Timolol 2.8 10.1016/J.STR.2008.05.001 2008-06-17
4U16 ACM3 M3 Acetylcholine (muscarinic) A (Rhodopsin) Rat BaculovirusSf9Insect 9 chemicals 9 steps sponge mesophaselipidic cubic phase (LCP)monoolein (9.9 MAG) 5 chems 7.5-7.5 298 K N-methylscopolamine (NMS) 3.7 10.1016/J.STR.2014.08.022 2014-11-26
5WS3 OX2R OX2 Orexin A (Rhodopsin) Human BaculovirusSf9Insect 9 chemicals 9 steps in meso/LCPlipidic cubic phase (LCP)monoolein (9.9 MAG) 4 chems 5.8-6.2 20°C EMPA 2.3 2017-12-13
2ZIY OPSD Rhodopsin Opsins A (Rhodopsin) Japanese flying squid NANativeSquid 1 chemicals 1 steps vapour diffusionHanging drops 5 chems 7.0-7.0 20°C 11-cis Retinal 3.7 10.1074/JBC.C800040200 2008-05-06
3C9M OPSD Rhodopsin Opsins A (Rhodopsin) Bovine NANANA 1 chemicals 1 steps NANANA 1 chems 0.0-0.0 NA 11-cis Retinal 3.4 10.1107/S0907444908017162 2008-08-05
3REY AA2AR A2A Adenosine A (Rhodopsin) Human BaculovirusSf9Insect 1 chemicals 1 steps vapour diffusionSitting drop 6 chems 8.0-8.8 4°C XAC(Xanthine amine congener ) 3.3 10.1016/J.STR.2011.06.014 2011-09-07
4K5Y CRFR1 CRF1 Corticotropin-releasing factor B1 (Secretin) Human BaculovirusHi5Insect 1 chemicals 1 steps in meso/LCPlipidic cubic phase (LCP)monoolein (9.9 MAG) 4 chems 5.5-5.5 22.5°C CP-376395 3.0 10.1038/NATURE12357 2013-07-17
5U09 CNR1 CB1 Cannabinoid A (Rhodopsin) Human BaculovirusSf21Insect 9 chemicals 9 steps in meso/LCPlipidic cubic phase (LCP)monoolein (9.9 MAG) 6 chems 5.5-5.5 20°C Ligand free 2.6 10.1038/NATURE20613 2016-12-07
5XR8 CNR1 CB1 Cannabinoid A (Rhodopsin) Human Transient_transfectionHEK293TMammalian 4 chemicals 4 steps in meso/LCPlipidic cubic phase (LCP)monoolein (9.9 MAG) 6 chems 6.2-6.2 20°C AM841 3.0 10.1038/NATURE23272 2017-07-12
3OE6 CXCR4 CXCR4 Chemokine A (Rhodopsin) Human BaculovirusSf9Insect 4 chemicals 4 steps in meso/LCPlipidic cubic phase (LCP)monoolein (9.9 MAG) 6 chems 5.5-5.5 20°C IT1t 3.2 10.1126/SCIENCE.1194396 2010-10-27
5GLH EDNRB ETB Endothelin A (Rhodopsin) Human BaculovirusSF+Insect 6 chemicals 6 steps in meso/LCPlipidic cubic phase (LCP)monoolein (9.9 MAG) 6 chems 6.0-6.0 20°C endothelin-1 2.8 10.1038/NATURE19319 2016-09-07
4YAY AGTR1 AT1 Angiotensin A (Rhodopsin) Human BaculovirusSf9Insect 2 chemicals 2 steps in meso/LCPlipidic cubic phasemonoolein (9.9 MAG) 6 chems 5.0-6.0 20°C ZD-7155 2.9 10.1016/J.CELL.2015.04.011 2015-04-22
3UZC AA2AR A2A Adenosine A (Rhodopsin) Human BaculovirusSf9Insect 1 chemicals 1 steps vapour diffusionsitting drop 6 chems 8.0-8.0 4°C T4E (4-(3-amino-5-phenyl-1,2,4-triazin-6.. 3.3 10.1021/JM201376W 2012-03-21
5NM2 AA2AR A2A Adenosine A (Rhodopsin) Human BaculovirusSf9Insect 1 chemicals 1 steps in meso/LCPlipidic cubic phase (LCP)monoolein (9.9 MAG) 5 chems 5.0-5.0 20°C ZM241385 2.0 10.1038/S41467-017-00630-4 2017-09-27
4AMJ ADRB1 β1 Adrenoceptors A (Rhodopsin) Common turkey BaculovirusHi5Insect 2 chemicals 2 steps vapour diffusionsitting drops 3 chems 9.0-9.0 4°C Carvedilol 2.3 10.1016/J.STR.2012.03.014 2012-05-23
3ZPQ ADRB1 β1 Adrenoceptors A (Rhodopsin) Common turkey BaculovirusHi5Insect 1 chemicals 1 steps vapour diffusionsitting drops 3 chems 9.0-9.0 4°C Ligand 19 [4-(1-Piperazinyl)-1H-indole,d.. 2.8 10.1021/JM400140Q 2013-04-03
3PXO OPSD Rhodopsin Opsins A (Rhodopsin) Bovine NANativeBovine 1 chemicals 1 steps vapour diffusionHanging drops 3 chems 5.0-5.8 4°C GaCT2 peptide 3.0 10.1038/NATURE09789 2011-03-09
5TE5 OPSD Rhodopsin Opsins A (Rhodopsin) Bovine NANativeBovine 1 chemicals 1 steps vapour diffusionHanging drop 4 chems 5.2-6.6 4°C 6-carbon ring retinal chromophore 4.0 10.1073/PNAS.1617446114 2017-03-15
3CAP OPSD Rhodopsin Opsins A (Rhodopsin) Bovine NANativeBovine 1 chemicals 1 steps vapour diffusionHanging drop 4 chems 5.6-5.6 4°C ligand free 2.9 10.1038/NATURE07063 2008-06-24
4UHR AA2AR A2A Adenosine A (Rhodopsin) Human BaculovirusHi5Insect 2 chemicals 2 steps in meso/LCPlipidic cubic phase (LCP)monoolein (9.9 MAG) 4 chems 4.8-4.8 22°C CGS 21680 2.6 10.1124/MOL.114.097360 2015-04-08
3SN6 ADRB2 β2 Adrenoceptors A (Rhodopsin) Human BaculovirusSf9Insect 2 chemicals 2 steps sponge mesophaselipidic cubic phase (LCP)7.7 MAG 6 chems 6.5-6.5 20°C BI-167107 3.2 10.1038/NATURE10361 2011-07-20
3V2W S1PR1 S1P1 Lysophospholipid (S1P) A (Rhodopsin) Human BaculovirusSf9Insect 2 chemicals 2 steps in meso/LCPlipidic cubic phase (LCP)monoolein (9.9 MAG) 5 chems 7.8-7.8 20°C ML056 3.4 10.1126/SCIENCE.1215904 2012-02-15
5UVI AA2AR A2A Adenosine A (Rhodopsin) Human BaculovirusSf9Insect 2 chemicals 2 steps in meso/LCPlipidic cubic phase (LCP)monoolein (9.9 MAG) 6 chems 5.0-5.0 20°C ZM241385 3.2 10.1107/S205225251700570X 2017-05-24
6B73 OPRK κ Opioid A (Rhodopsin) Human 1 chemicals 1 steps 1 chems 0.0-0.0 3.1 10.1016/J.CELL.2017.12.011 2018-01-17
1F88 OPSD Rhodopsin Opsins A (Rhodopsin) Bovine NANativeBovine 2 chemicals 2 steps vapour diffusionHanging drop 7 chems 6.0-6.0 4°C 11-cis Retinal 2.8 10.1126/SCIENCE.289.5480.739 2000-08-04
4L6R GLR glucagon Glucagon receptor family B1 (Secretin) Human BaculovirusSf9Insect 4 chemicals 4 steps in meso/LCPlipidic cubic phase (LCP)monoolein (9.9 MAG) 6 chems 7.0-7.0 20°C NNC0640 (Glucagon Receptor Antagonist I).. 3.3 10.1038/NATURE12393 2013-07-24
4ZWJ OPSD Rhodopsin Opsins A (Rhodopsin) Human Transient_transfectionHEK293S(TetR)-GnTI-Mammalian 2 chemicals 2 steps in meso/LCPlipidic cubic phase (LCP)monopalmitolein (9.7 MAG) 5 chems 5.0-5.0 20°C all trans retinal 3.3 10.1038/NATURE14656 2015-07-29
4DAJ ACM3 M3 Acetylcholine (muscarinic) A (Rhodopsin) Rat BaculovirusSf9Insect 6 chemicals 6 steps in meso/LCPlipidic cubic phase (LCP)monoolein (9.9 MAG) 6 chems 7.5-7.5 22°C Tiotropium 3.4 10.1038/NATURE10867 2012-02-22
4J4Q OPSD Rhodopsin Opsins A (Rhodopsin) Bovine NANativeBovine 1 chemicals 1 steps vapour diffusionHanging drop 3 chems 5.2-6.0 4°C GaCT2 peptide binding partner 2.7 10.1002/ANIE.201302374 2013-10-30
5K2A AA2AR A2A Adenosine A (Rhodopsin) Human BaculovirusSf9Insect 2 chemicals 2 steps in meso/LCPlipidic cubic phase (LCP)monoolein (9.9 MAG) 5 chems 5.0-5.0 20°C ZM241385 2.5 10.1126/SCIADV.1600292 2016-09-21
4RWS CXCR4 CXCR4 Chemokine A (Rhodopsin) Human BaculovirusSf9Insect 2 chemicals 2 steps in meso/LCPlipidic cubic phase (LCP)monoolein (9.9 MAG) 6 chems 5.5-5.5 20°C vMIP-II, CC chemokine encoded by Kaposiâ.. 3.1 10.1126/SCIENCE.1261064 2015-02-11
4GRV NTR1 NTS1 Neurotensin A (Rhodopsin) Rat BaculovirusTni PRO (Trichoplusia ni) cell linesInsect 2 chemicals 2 steps in meso/LCPlipidic cubic phase (LCP)monoolein (9.9 MAG) 6 chems 7.0-7.0 20°C neurotensin-(8-13) 2.8 10.1038/NATURE11558 2012-10-17
4BVN ADRB1 β1 Adrenoceptors A (Rhodopsin) Common turkey BaculovirusHi5Insect 4 chemicals 4 steps in meso/LCPlipidic cubic phase (LCP)monoolein (9.9 MAG) 4 chems 7.0-7.0 22°C cyanopindolol 2.1 10.1371/JOURNAL.PONE.0092727 2014-04-02
4Z34 LPAR1 LPA1 Lysophospholipid (LPA) A (Rhodopsin) Human BaculovirusSf9Insect 2 chemicals 2 steps in meso/LCPlipidic cubic phase (LCP)monoolein (9.9 MAG) 5 chems 5.5-5.5 20°C ONO-9780307 3.0 10.1016/J.CELL.2015.06.002 2015-06-03
5D5B ADRB2 β2 Adrenoceptors A (Rhodopsin) Human BaculovirusSf9Insect 1 chemicals 1 steps in meso/LCPlipidic cubic phase (LCP)monoolein (9.9 MAG) 5 chems 6.5-7.0 20°C Carazolol 3.8 10.1107/S2059798315021683 2016-01-13
5TZY FFAR1 FFA1 Free fatty acid A (Rhodopsin) Human BaculovirusSf21Insect 4 chemicals 4 steps in meso/LCPlipidic cubic phase (LCP)monoolein (9.9 MAG) 5 chems 6.3-6.8 20°C MK-8666 3.2 10.1038/NSMB.3417 2017-06-07
3NYA ADRB2 β2 Adrenoceptors A (Rhodopsin) Human BaculovirusSf9Insect 4 chemicals 4 steps in meso/LCPlipidic cubic phase (LCP)monoolein (9.9 MAG) 6 chems 7.0-7.0 21-23°C Alprenolol 3.2 10.1021/JA105108Q 2010-08-11
5XEZ GLR glucagon Glucagon receptor family B1 (Secretin) Human BaculovirusSf9Insect 4 chemicals 4 steps in meso/LCPlipidic cubic phase (LCP)monoolein (9.9 MAG) 6 chems 7.0-7.0 20°C NNC0640 3.0 10.1038/NATURE22363 2017-05-24
5O9H C5AR1 C5a1 Complement peptide A (Rhodopsin) Human BaculovirusSf9Insect 2 chemicals 2 steps in meso/LCPlipidic cubic phasemonoolein (9.9 MAG) 5 chems 5.5-6.0 22.5°C NDT9513727 2.7 10.1038/NATURE25025 2018-01-10
4PY0 P2Y12 P2Y12 P2Y A (Rhodopsin) Human BaculovirusSf9Insect 6 chemicals 6 steps in meso/LCPlipidic cubic phase (LCP)monoolein (9.9 MAG) 6 chems 5.0-6.0 20°C 2MeSATP 3.1 10.1038/NATURE13288 2014-04-30
2I37 OPSD Rhodopsin Opsins A (Rhodopsin) Bovine NANativeBovine 2 chemicals 2 steps vapour diffusionsitting drops 5 chems 7.0-8.0 5°C All-trans retinal 4.2 10.1073/PNAS.0608022103 2006-10-17
5VEX GLP1R GLP-1 Glucagon receptor family B1 (Secretin) Human BaculovirusSf9Insect 2 chemicals 2 steps in meso/LCPlipidic cubic phase (LCP)monoolein (9.9 MAG) 5 chems 5.0-5.8 20°C NNC0640 3.0 10.1038/NATURE22378 2017-05-17
1L9H OPSD Rhodopsin Opsins A (Rhodopsin) Bovine NANativeBovine 1 chemicals 1 steps vapour diffusionHanging drops 5 chems 6.0-6.0 4°C 11-cis Retinal 2.6 10.1073/PNAS.082666399 2002-05-15
5K2D AA2AR A2A Adenosine A (Rhodopsin) Human BaculovirusSf9Insect 2 chemicals 2 steps in meso/LCPlipidic cubic phase (LCP)monoolein (9.9 MAG) 5 chems 5.0-5.0 20°C ZM241385 1.9 10.1126/SCIADV.1600292 2016-09-21
2PED OPSD Rhodopsin Opsins A (Rhodopsin) Bovine NANativeBovine 1 chemicals 1 steps vapour diffusionHanging drop 5 chems 6.4-6.4 283 K 9-cis Retinal 3.0 10.1529/BIOPHYSJ.107.108225 2007-10-30
6FKD OPSD Rhodopsin Opsins A (Rhodopsin) Bovine N/A N/A N/A N/A N/A N/A N/A N/A N/A N/A N/A N/A 2.5 10.1073/PNAS.1718084115 2018-04-04
4O9R SMO SMO Frizzled F (Frizzled) Human BaculovirusSf9Insect 2 chemicals 2 steps in meso/LCPlipidic cubic phasemonoolein (9.9 MAG) 5 chems 7.4-7.4 20°C cyclopamine 3.2 10.1038/NCOMMS4309 2014-03-05
4ZJC OX1R OX1 Orexin A (Rhodopsin) Human BaculovirusSf9Insect 6 chemicals 6 steps in meso/LCPlipidic cubic phase (LCP)monoolein (9.9 MAG) 5 chems 5.6-5.6 20°C SB-674042 2.8 10.1038/NSMB.3183 2016-03-09
5WQC OX2R OX2 Orexin A (Rhodopsin) Human BaculovirusSf9Insect 9 chemicals 9 steps in meso/LCPlipidic cubic phasemonoolein (9.9 MAG) 4 chems 5.8-6.2 20°C EMPA 2.0 10.1016/J.STR.2017.11.005 2017-11-29
4ZJ8 OX1R OX1 Orexin A (Rhodopsin) Human BaculovirusSf9Insect 6 chemicals 6 steps in meso/LCPlipidic cubic phase (LCP)monoolein (9.9 MAG) 5 chems 5.4-5.4 20°C Suvorexant 2.8 10.1038/NSMB.3183 2016-03-09
5DSG ACM4 M4 Acetylcholine (muscarinic) A (Rhodopsin) Human BaculovirusSf9Insect 4 chemicals 4 steps in meso/LCPlipidic cubic phase (LCP)monoolein (9.9 MAG) 5 chems 5.5-8.0 20°C Tiotropium 2.6 10.1038/NATURE17188 2016-03-16
5TE3 OPSD Rhodopsin Opsins A (Rhodopsin) Bovine NANativeBovine 1 chemicals 1 steps vapour diffusionHanging drop 4 chems 5.2-6.6 4°C 11 cis-retinal 2.7 10.1073/PNAS.1617446114 2017-03-15
2YCX ADRB1 β1 Adrenoceptors A (Rhodopsin) Common turkey BaculovirusHi5Insect 2 chemicals 2 steps vapour diffusionNA 3 chems 6.9-7.3 NA cyanopindolol 3.3 10.1073/PNAS.1100185108 2011-06-01
5DGY OPSD Rhodopsin Opsins A (Rhodopsin) Human Transient_transfectionHEK293SMammalian 2 chemicals 2 steps in meso/LCPlipidic cubic phase (LCP)monopalmitolein (9.7 MAG) 5 chems 5.0-5.0 20°C all-trans retinal 7.7 10.1038/SDATA.2016.21 2016-03-23
5WF6 AA2AR A2A Adenosine A (Rhodopsin) Human 1 chemicals 1 steps 1 chems 0.0-0.0 2.9 10.1016/J.STR.2017.12.013 2018-02-21
4QKX ADRB2 β2 Adrenoceptors A (Rhodopsin) Human BaculovirusSf9Insect 1 chemicals 1 steps in meso/LCPlipidic cubic phase (LCP)7.7 MAG 5 chems 7.8-8.4 20°C adrenaline covalent ligand 2 3.3 10.1073/PNAS.1410415111 2014-07-23
2Z73 OPSD Rhodopsin Opsins A (Rhodopsin) Japanese flying squid NANativeSquid 1 chemicals 1 steps vapour diffusionsitting drops 5 chems 6.4-6.4 4°C 11-cis Retinal 2.5 10.1038/NATURE06925 2008-05-13
4MQT ACM2 M2 Acetylcholine (muscarinic) A (Rhodopsin) Human BaculovirusSf9Insect 2 chemicals 2 steps in meso/LCPlipidic cubic phase (LCP)monoolein (9.9 MAG) 6 chems 7.2-7.9 20°C allosteric modulator LY2119620 3.7 10.1038/NATURE12735 2013-11-27
3RZE HRH1 H1 Histamine A (Rhodopsin) Human Pichia PastorisP. pastoris SMD1163Yeast 4 chemicals 4 steps in meso/LCPlipidic cubic phase (LCP)monoolein (9.9 MAG) 6 chems 4.5-4.5 20-22°C Doxepin 3.1 10.1038/NATURE10236 2011-06-15
4EJ4 OPRD δ Opioid A (Rhodopsin) Mouse BaculovirusSf9Insect 4 chemicals 4 steps in meso/LCPlipidic cubic phase (LCP)monoolein (9.9 MAG) 6 chems 7.5-7.5 20°C Naltrindole 3.4 10.1038/NATURE11111 2012-05-16
5TZR FFAR1 FFA1 Free fatty acid A (Rhodopsin) Human BaculovirusSf21Insect 4 chemicals 4 steps in meso/LCPlipidic cubic phase (LCP)monoolein (9.9 MAG) 5 chems 7.7-8.3 20°C MK-8666 2.2 10.1038/NSMB.3417 2017-06-07
2Y02 ADRB1 β1 Adrenoceptors A (Rhodopsin) Common turkey BaculovirusHi5Insect 1 chemicals 1 steps vapour diffusionsitting drops 6 chems 9.0-9.0 4°C Carmoterol 2.6 10.1038/NATURE09746 2011-01-12
4GPO ADRB1 β1 Adrenoceptors A (Rhodopsin) Common turkey BaculovirusHi5Insect 1 chemicals 1 steps vapour diffusionHanging drops 5 chems 3.6-4.0 18°C Ligand free 3.5 10.1038/NSMB.2504 2013-02-27
3ZPR ADRB1 β1 Adrenoceptors A (Rhodopsin) Common turkey BaculovirusHi5Insect 1 chemicals 1 steps vapour diffusionsitting drops 3 chems 9.0-9.0 4°C Ligand 20 [4-Methyl-2-piperazin-1-yl-qui.. 2.7 10.1021/JM400140Q 2013-04-03
5UNF AGTR2 AT2 Angiotensin A (Rhodopsin) Human BaculovirusSf21Insect 4 chemicals 4 steps in meso/LCPlipidic cubic phasemonoolein (9.9 MAG) 7 chems 8.0-8.0 20°C compound 1 (N-benzyl-N-(2-ethyl-4-oxo-3-.. 2.8 10.1038/NATURE22035 2017-04-05
3DQB OPSD Rhodopsin Opsins A (Rhodopsin) Bovine NANativeBovine 1 chemicals 1 steps vapour diffusionhanging drops 5 chems 5.9-6.1 10°C Gta peptide 3.2 10.1038/NATURE07330 2008-09-23
4UG2 AA2AR A2A Adenosine A (Rhodopsin) Human BaculovirusHi5Insect 2 chemicals 2 steps in meso/LCPlipidic cubic phase (LCP)monoolein (9.9 MAG) 3 chems 7.0-7.0 22°C CGS 21680 2.6 10.1124/MOL.114.097360 2015-04-08
5VRA AA2AR A2A Adenosine A (Rhodopsin) Human BaculovirusSf9Insect 2 chemicals 2 steps in meso/LCPlipidic cubic phasemonoolein (9.9 MAG) 7 chems 4.6-5.0 20°C ZM241385 2.4 10.1038/NPROT.2017.135 2017-12-13
6FK8 OPSD Rhodopsin Opsins A (Rhodopsin) Bovine N/A N/A N/A N/A N/A N/A N/A N/A N/A N/A N/A N/A 2.9 10.1073/PNAS.1718084115 2018-04-04
5OLH AA2AR A2A Adenosine A (Rhodopsin) Human 1 chemicals 1 steps 1 chems 0.0-0.0 Vipadenant (24 hour soak) 2.6 10.1038/S41598-017-18570-W 2018-01-17
2I35 OPSD Rhodopsin Opsins A (Rhodopsin) Bovine NANativeBovine 2 chemicals 2 steps vapour diffusionsitting drops 5 chems 7.0-8.0 5°C all-trans retinal 3.8 10.1073/PNAS.0608022103 2006-10-17
5UIG AA2AR A2A Adenosine A (Rhodopsin) Human BaculovirusSf9Insect 4 chemicals 4 steps vapour diffusionSitting drop 6 chems 7.0-7.0 20°C Cmpd-1 3.5 10.1073/PNAS.1621423114 2017-02-08
5CXV ACM1 M1 Acetylcholine (muscarinic) A (Rhodopsin) Human BaculovirusSf9Insect 2 chemicals 2 steps in meso/LCPlipidic cubic phase (LCP)monoolein (9.9 MAG) 5 chems 8.0-8.0 20°C Tiotropium 2.7 10.1038/NATURE17188 2016-03-09
3P0G ADRB2 β2 Adrenoceptors A (Rhodopsin) Human BaculovirusSf9Insect 2 chemicals 2 steps in meso/LCPlipidic cubic phase (LCP)monoolein (9.9 MAG) 5 chems 8.0-8.0 20°C BI-167107 3.5 10.1038/NATURE09648 2011-01-19
5CGC GRM5 mGlu5 Metabotropic glutamate C (Glutamate) Human BaculovirusSf21Insect 1 chemicals 1 steps in meso/LCPlipidic cubic phase (LCP)monoolein (9.9 MAG) 4 chems 5.5-6.8 20°C Compound 14 3.1 10.1021/ACS.JMEDCHEM.5B00892 2015-08-12
5IU7 AA2AR A2A Adenosine A (Rhodopsin) Human BaculovirusTni PRO (Trichoplusia ni) cell linesInsect 1 chemicals 1 steps in meso/LCPlipidic cubic phase (LCP)monoolein (9.9 MAG) 5 chems 5.3-5.4 20°C 12c 1.9 10.1021/ACS.JMEDCHEM.6B00653 2016-06-29
3C9L OPSD Rhodopsin Opsins A (Rhodopsin) Bovine NANANA 1 chemicals 1 steps NANANA 1 chems 0.0-0.0 NA 11 cis-retinal 2.7 10.1107/S0907444908017162 2008-08-05
4BEY OPSD Rhodopsin Opsins A (Rhodopsin) Bovine Stable_cellsHEK293S(TetR)GnTI-Mammalian 1 chemicals 1 steps vapour diffusionsitting drop 4 chems 4.5-4.5 20°C GaCT2 peptide 2.9 10.1038/EMBOR.2013.44 2013-05-08
5IUA AA2AR A2A Adenosine A (Rhodopsin) Human BaculovirusTni PRO (Trichoplusia ni) cell linesInsect 1 chemicals 1 steps in meso/LCPlipidic cubic phase (LCP)monoolein (9.9 MAG) 5 chems 5.3-5.4 20 12b 2.2 10.1021/ACS.JMEDCHEM.6B00653 2016-06-29
6BQG 5HT2C 5-HT2C 5-Hydroxytryptamine A (Rhodopsin) Human BaculovirusSf9Insect 2 chemicals 2 steps in meso/LCPlipidic cubic phasemonoolein (9.9 MAG) 5 chems 6.0-6.0 20°C Ergotamine 3.0 10.1016/J.CELL.2018.01.001 2018-02-14
5OM4 AA2AR A2A Adenosine A (Rhodopsin) Human 1 chemicals 1 steps 1 chems 0.0-0.0 Compound 4e (24 hour soak) 2.0 10.1038/S41598-017-18570-W 2018-01-17
6BQH 5HT2C 5-HT2C 5-Hydroxytryptamine A (Rhodopsin) Human BaculovirusSf9Insect 2 chemicals 2 steps in meso/LCPlipidic cubic phasemonoolein (9.9 MAG) 5 chems 6.0-6.0 20°C Ritanserin 2.7 10.1016/J.CELL.2018.01.001 2018-02-14
5DHH OPRX NOP Opioid A (Rhodopsin) Human BaculovirusSf9Insect 2 chemicals 2 steps in meso/LCPlipidic cubic phase (LCP)monoolein (9.9 MAG) 5 chems 6.4-6.4 20°C SB-612111 3.0 10.1016/J.STR.2015.07.024 2015-10-21
5NDD PAR2 PAR2 Proteinase-activated A (Rhodopsin) Human BaculovirusSf9Insect 2 chemicals 2 steps in meso/LCPlipidic cubic phase (LCP)monoolein (9.9 MAG) 6 chems 5.5-6.2 20°C AZ8838 (formulae : (R)-(4-fluoro-2-propy.. 2.8 10.1038/NATURE22309 2017-05-03
6B3J GLP1R GLP-1 Glucagon receptor family B1 (Secretin) Human BaculovirusTni PRO (Trichoplusia ni) cell linesInsect 2 chemicals 2 steps Cryo-EMVolta phase plate (FEI) 5 chems 7.4-7.4 4°C ExP5 3.3 10.1038/NATURE25773 2018-02-21
5UNH AGTR2 AT2 Angiotensin A (Rhodopsin) Human BaculovirusSf21Insect 4 chemicals 4 steps in meso/LCPlipidic cubic phasemonoolein (9.9 MAG) 7 chems 8.0-8.0 20°C compound 2 (N-[(furan-2-yl)methyl]-N-(4-.. 2.9 10.1038/NATURE22035 2017-04-05
3PWH AA2AR A2A Adenosine A (Rhodopsin) Human BaculovirusSf9Insect 1 chemicals 1 steps vapour diffusionsitting drop 6 chems 8.0-8.8 4°C ZM-241385 3.3 10.1016/J.STR.2011.06.014 2011-09-07
4JKV SMO SMO Frizzled F (Frizzled) Human BaculovirusSf9Insect 4 chemicals 4 steps in meso/LCPlipidic cubic phasemonoolein (9.9 MAG) 6 chems 7.4-7.4 20°C LY2940680_1 2.5 10.1038/NATURE12167 2013-04-24
4IAQ 5HT1B 5-HT1B 5-Hydroxytryptamine A (Rhodopsin) Human BaculovirusSf9Insect 4 chemicals 4 steps in meso/LCPlipidic cubic phase (LCP)monoolein (9.9 MAG) 6 chems 8.7-8.7 20°C Dihydroergotamine 2.8 10.1126/SCIENCE.1232807 2013-03-13
4A4M OPSD Rhodopsin Opsins A (Rhodopsin) Bovine Stable_cellsHEK293TMammalian 1 chemicals 1 steps vapour diffusionsitting drop 3 chems 4.5-4.5 4°C all-trans retinal 3.3 10.1073/PNAS.1114089108 2012-01-25
2G87 OPSD Rhodopsin Opsins A (Rhodopsin) Bovine NANativeBovine 1 chemicals 1 steps vapour diffusionHanging drops 5 chems 6.5-7.5 283 K all trans retinal 2.6 10.1002/ANIE.200600595 2006-09-02
6FK6 OPSD Rhodopsin Opsins A (Rhodopsin) Bovine N/A N/A N/A N/A N/A N/A N/A N/A N/A N/A N/A N/A 2.4 10.1073/PNAS.1718084115 2018-04-04
2Y04 ADRB1 β1 Adrenoceptors A (Rhodopsin) Common turkey BaculovirusHi5Insect 1 chemicals 1 steps vapour diffusionsitting drops 6 chems 9.0-9.0 4°C Salbutamol 3.1 2011-01-12
6FKC OPSD Rhodopsin Opsins A (Rhodopsin) Bovine N/A N/A N/A N/A N/A N/A N/A N/A N/A N/A N/A N/A 2.5 10.1073/PNAS.1718084115 2018-04-04
5X93 EDNRB ETB Endothelin A (Rhodopsin) Human BaculovirusSf9Insect 4 chemicals 4 steps in meso/LCPlipidic cubic phase (LCP)monoolein (9.9 MAG) 5 chems 7.0-7.0 20°C K-8794 2.2 10.1038/NSMB.3450 2017-08-16
2YDV AA2AR A2A Adenosine A (Rhodopsin) Human BaculovirusHi5Insect 4 chemicals 4 steps vapour diffusionsitting drop 5 chems 6.4-6.4 4°C NECA 2.6 10.1038/NATURE10136 2011-05-18
3AYM OPSD Rhodopsin Opsins A (Rhodopsin) Japanese flying squid NANativeSquid 1 chemicals 1 steps vapour diffusionsitting drop 5 chems 6.6-6.6 4°C All-trans retinal 2.8 10.1016/J.JMB.2011.08.044 2011-08-17
3ODU CXCR4 CXCR4 Chemokine A (Rhodopsin) Human BaculovirusSf9Insect 4 chemicals 4 steps in meso/LCPlipidic cubic phase (LCP)monoolein (9.9 MAG) 6 chems 5.5-5.5 20°C IT1t 2.5 10.1126/SCIENCE.1194396 2010-10-27
3VW7 PAR1 PAR1 Proteinase-activated A (Rhodopsin) Human BaculovirusSf9Insect 6 chemicals 6 steps in meso/LCPlipidic cubic phase (LCP)monoolein (9.9 MAG) 5 chems 6.0-6.5 20°C Vorapaxar 2.2 10.1038/NATURE11701 2012-12-12
5TGZ CNR1 CB1 Cannabinoid A (Rhodopsin) Human Transient_transfectionHEK293FMammalian 4 chemicals 4 steps in meso/LCPlipidic cubic phase (LCP)monoolein (9.9 MAG) 6 chems 7.0-7.4 20°C AM6538 2.8 10.1016/J.CELL.2016.10.004 2016-11-02
5V57 SMO SMO Frizzled F (Frizzled) Human 1 chemicals 1 steps 1 chems 0.0-0.0 3.0 10.1038/NCOMMS15383 2017-05-24