Mutations

Position
NTR1 NTS1 7x37 354 TM7 T S receptor-expression 4BWB, 4BV0
NTR1 NTS1 2x60 124 TM2 E D receptor-expression 4BWB, 4BV0
GLP1R GLP-1 5x52 318 TM5 G I thermostabilising 5VEW, 5VEX
NTR1 NTS1 213 ECL2 R L receptor-expression 4BUO, 3ZEV, 4BWB, 4BV0
C5AR1 C5a1 5x68 232 TM5 R A palmitoylation-site 5O9H
LPAR1 LPA1 5x37 204 TM5 D C thermostabilising, receptor-disulfide-bridge 4Z36
NTR1 NTS1 2x42 105 TM2 H Y receptor-expression 4BUO, 3ZEV, 4BWB, 4BV0
NTR1 NTS1 6x59 332 TM6 C V receptor-expression 4BWB, 4BV0
FFAR1 FFA1 5x58 202 TM5 Y F thermostabilising 4PHU, 5TZY, 5KW2, 5TZR
CNR1 CB1 5x47 283 TM5 T V receptor-expression 5XR8, 5XRA, 5TGZ
OPSD Rhodopsin 338 C-term S X phosphorylation-site 5W0P
NTR1 NTS1 1x54 86 TM1 A L thermostabilising 4BUO, 3ZEV, 4BWB, 5T04, 4GRV, 4XES, 4XEE, 4BV0
APJ apelin 8x59 325 H8 C L palmitoylation-site 5VBL
PAR2 PAR2 3x51 174 TM3 Y A thermostabilising 5NJ6, 5NDD, 5NDZ
GLP1R GLP-1 260 ICL2 L F thermostabilising, other-effect 5NX2
ADRB1 β1 1x59 68 TM1 R S thermostabilising 4AMI, 4GPO, 2YCY, 5A8E, 2Y03, 2YCW, 2Y02, 3ZPR, 3ZPQ, 4AMJ, 5F8U, 2YCZ, 2Y04, 2Y00, 4BVN, 2YCX, 2Y01, 2VT4
PAR2 PAR2 3x53 176 TM3 V E thermostabilising 5NJ6, 5NDD, 5NDZ
NTR1 NTS1 5x42 240 TM5 V L receptor-expression 4BWB, 4BV0
AA2AR A2A 3x55 107 TM3 R A thermostabilising 5NM4, 5N2R, 3UZC, 5IU4, 5MZJ, 5OLG, 3UZA, 5OLO, 5IUA, 5OM4, 5NM2, 3REY, 5IU7, 5IUB, 5OM1, 5OLH, 5OLZ, 5NLX, 3RFM, 5MZP, 3PWH, 5OLV, 5IU8
NTR1 NTS1 2x40 103 TM2 H D receptor-expression 4BUO, 3ZEV, 4BWB, 4BV0
CCR9 CCR9 8x63 337 H8 C A palmitoylation-site 5LWE
OPSD Rhodopsin 2x56 90 TM2 G D natural-mutation-snp-incl-disease-causing 4BEZ, 4BEY
OPSD Rhodopsin 282 ECL3 N C thermostabilising, receptor-disulfide-bridge 6CMO, 5DGY, 4ZWJ, 5W0P
AA2AR A2A 2x50 52 TM2 D N thermostabilising 5WF5
CCR9 CCR9 5x41 216 TM5 T A thermostabilising 5LWE
CXCR4 CXCR4 3x41 125 TM3 L W thermostabilising 3ODU, 3OE0, 3OE8, 3OE6, 3OE9, 4RWS
ADRB1 β1 2x53 90 TM2 M V thermostabilising 4AMI, 4GPO, 2YCY, 5A8E, 2Y03, 2YCW, 2Y02, 3ZPR, 3ZPQ, 4AMJ, 5F8U, 2YCZ, 2Y04, 2Y00, 4BVN, 2YCX, 2Y01, 2VT4
GLR glucagon 2x39 173 TM2 R A thermostabilising 5YQZ, 5EE7
GLP1R GLP-1 6x47 363 TM6 H V thermostabilising 5NX2
GRM5 mGlu5 5x53 753 TM5 S A thermostabilising 6FFH, 5CGC, 6FFI, 5CGD, 4OO9
LPAR1 LPA1 6x59 282 TM6 V C thermostabilising, receptor-disulfide-bridge 4Z36
ADRB2 β2 6x27 265 TM6 C A other-effect 4QKX, 4LDL, 4LDO, 5JQH, 4LDE
5HT2B 5-HT2B 3x41 144 TM3 M W thermostabilising 5TVN, 5TUD, 4IB4, 4NC3
AA2AR A2A 3x36 88 TM3 T A thermostabilising 5NM4, 5N2R, 3UZC, 5IU4, 5MZJ, 5OLG, 3UZA, 5OLO, 5IUA, 5OM4, 5NM2, 3REY, 5IU7, 5IUB, 5OM1, 5OLH, 5OLZ, 5NLX, 3RFM, 5MZP, 3PWH, 5OLV, 5IU8
NTR1 NTS1 5x63 262 TM5 N R receptor-expression 4BWB, 4BV0
ADRB2 β2 16 N-term G R other-effect 2R4R, 3NY9, 3D4S, 5D6L, 5D5B, 3NYA, 3NY8, 2RH1, 3KJ6, 3P0G, 5D5A, 5X7D
NTR1 NTS1 3x55 172 TM3 C R receptor-expression 4BV0
OPSD Rhodopsin 336 C-term T X phosphorylation-site 5W0P
APJ apelin 3x40 117 TM3 V A thermostabilising 5VBL
GLR glucagon 2x48 182 TM2 A L thermostabilising 5EE7
GLP1R GLP-1 3x24 225 TM3 S A thermostabilising 5VEW, 5VEX
GLP1R GLP-1 4x48 271 TM4 S A thermostabilising 5VEW, 5VEX
GLP1R GLP-1 45x52 298 ECL2 T A thermostabilising 5NX2
ACM2 M2 2 N-term N D glycosylation-site 3UON, 4MQT, 4MQS
AA2AR A2A 5x63 202 TM5 L A thermostabilising 5NM4, 5N2R, 3UZC, 5IU4, 5MZJ, 5OLG, 3UZA, 5OLO, 5IUA, 5OM4, 5NM2, 3REY, 5IU7, 5IUB, 5OM1, 5OLH, 5OLZ, 5NLX, 3RFM, 5MZP, 3PWH, 5OLV, 5IU8
AA1R A1 6x41 240 TM6 L A thermostabilising 5N2S
NTR1 NTS1 5x64 263 TM5 K R receptor-expression 4BWB, 4BV0
PAR1 PAR1 259 ECL2 N S glycosylation-site 3VW7
GLR glucagon 6x48 362 TM6 E F thermostabilising 5EE7
AA2AR A2A 4x43 122 TM4 K A thermostabilising 5NM4, 5N2R, 3UZC, 5IU4, 5MZJ, 5OLG, 3UZA, 5OLO, 5IUA, 5OM4, 5NM2, 3REY, 5IU7, 5IUB, 5OM1, 5OLH, 5OLZ, 5NLX, 3RFM, 5MZP, 3PWH, 5OLV, 5IU8
CCR9 CCR9 12x50 79 ICL1 V A thermostabilising 5LWE
CCR9 CCR9 3x47 141 TM3 S C thermostabilising 5LWE
CRFR1 CRF1 6x51 330 TM6 F A thermostabilising 4K5Y, 4Z9G
NTR1 NTS1 7x41 358 TM7 F V receptor-expression 4BUO, 3ZEV, 4BWB, 4BV0
C5AR1 C5a1 2x59 91 TM2 I A palmitoylation-site 5O9H
AA2AR A2A 154 ECL2 N Q glycosylation-site 3VGA, 3VG9
5HT2C 5-HT2C 7x45 360 TM7 C N receptor-expression, thermostabilising 6BQH, 6BQG
ADRB2 β2 2x63 93 TM2 H C thermostabilising, receptor-ligand-bond 4QKX, 3PDS
ADRB1 β1 7x36 327 TM7 F A thermostabilising 4AMI, 4GPO, 2YCY, 5A8E, 2Y03, 2YCW, 2Y02, 3ZPR, 3ZPQ, 4AMJ, 5F8U, 2YCZ, 2Y04, 2Y00, 4BVN, 2YCX, 2Y01, 2VT4
CCR9 CCR9 34 N-term T E glycosylation-site 5LWE
C5AR1 C5a1 34x51 142 ICL2 I A palmitoylation-site 5O9H
CCR5 CCR5 4x61 163 TM4 G N thermostabilising 5UIW, 4MBS
GLR glucagon 2x56 190 TM2 S A thermostabilising 5EE7
CCR9 CCR9 7x39 304 TM7 T A thermostabilising 5LWE
OX2R OX2 6x39 308 TM6 I V other-effect 5WQC, 4S0V, 5WS3
GLR glucagon 3x24 223 TM3 G A thermostabilising 5EE7
ADRB2 β2 187 ECL2 N E glycosylation-site 5X7D, 3D4S, 3NY9, 5D6L, 5D5B, 4GBR, 3NYA, 3NY8, 3SN6, 2RH1, 3KJ6, 4QKX, 4LDO, 4LDE, 4LDL, 3PDS, 3P0G, 5D5A, 5JQH
GLR glucagon 2x59 193 TM2 V F thermostabilising 5EE7
AA1R A1 6x37 236 TM6 L A thermostabilising 5N2S
5HT1B 5-HT1B 3x41 138 TM3 L W thermostabilising 6G79, 4IAR, 5V54, 4IAQ
NTR1 NTS1 2x61 125 TM2 L V receptor-expression 4BV0
AA1R A1 8x64 309 H8 C S palmitoylation-site 5N2S
GLR glucagon 207 ECL1 G E thermostabilising 5EE7
PAR2 PAR2 5x64 268 TM5 M A thermostabilising 5NJ6, 5NDD, 5NDZ
PAR2 PAR2 2x37 108 TM2 H A thermostabilising 5NJ6, 5NDD, 5NDZ
CNR1 CB1 3x46 210 TM3 T A thermostabilising 5XR8, 5XRA, 5U09, 5TGZ
ACM1 M1 12 N-term N Q glycosylation-site 5CXV
GLP1R GLP-1 6x45 361 TM6 G A thermostabilising 5NX2
ACM2 M2 373 ICL3 A T other-effect 4MQT, 4MQS
CCR9 CCR9 2x38 82 TM2 M A thermostabilising 5LWE
AA2AR A2A 3x37 89 TM3 Q A thermostabilising 2YDO, 4UG2, 4UHR, 2YDV
ADRB1 β1 5x58 227 TM5 Y A thermostabilising 4AMI, 4GPO, 2YCY, 5A8E, 2Y03, 2YCW, 2Y02, 3ZPR, 3ZPQ, 4AMJ, 5F8U, 2YCZ, 2Y04, 2Y00, 4BVN, 2YCX, 2Y01, 2VT4
GLP1R GLP-1 295 ECL2 G A thermostabilising 5NX2
CNR1 CB1 6x32 340 TM6 R E receptor-expression, thermostabilising 5XR8, 5XRA, 5TGZ
EDNRB ETB 1x55 124 TM1 R Y thermostabilising 5X93, 5XPR
GLP1R GLP-1 215 ECL1 D R thermostabilising 5NX2
GRM5 mGlu5 3x48 667 TM3 N Y thermostabilising 6FFH, 5CGC, 6FFI, 5CGD, 4OO9
CRFR1 CRF1 5x48 277 TM5 I A thermostabilising 4K5Y, 4Z9G
OPSD Rhodopsin 2x60 94 TM2 T I thermostabilising 5EN0, 5DYS
GLP1R GLP-1 6x45 361 TM6 G C thermostabilising 5VEW, 5VEX
CRFR1 CRF1 6x30 309 TM6 Y A thermostabilising 4K5Y, 4Z9G
AA1R A1 159 ECL2 N A glycosylation-site 5UEN, 5N2S
C5AR1 C5a1 317 C-term S E palmitoylation-site 5O9H
C5AR1 C5a1 8x54 311 H8 L E palmitoylation-site 5O9H
NTR1 NTS1 6x32 305 TM6 H R receptor-expression 4BUO, 3ZEV, 4BWB, 4BV0
ADRB1 β1 3x27 116 TM3 C L receptor-expression 4AMI, 4GPO, 2YCY, 5A8E, 2Y03, 2YCW, 2Y02, 3ZPR, 3ZPQ, 4AMJ, 5F8U, 2YCZ, 2Y04, 2Y00, 4BVN, 2YCX, 2Y01, 2VT4
ADRB1 β1 3x41 130 TM3 E W thermostabilising 5A8E
OPSD Rhodopsin 3x28 113 TM3 E Q thermostabilising 2X72
PAR2 PAR2 3x43 166 TM3 M L thermostabilising 5NJ6, 5NDD, 5NDZ
EDNRB ETB 7x48 381 TM7 I A thermostabilising 5X93, 5XPR
CCR9 CCR9 7x29 294 TM7 N A thermostabilising 5LWE
NTR1 NTS1 7x41 358 TM7 F A receptor-expression 5T04, 4GRV
GLP1R GLP-1 2x56 193 TM2 S C thermostabilising 5VEW, 5VEX
AA2AR A2A 2x52 54 TM2 A L thermostabilising 5NM4, 5N2R, 3UZC, 5IU4, 5MZJ, 5OLG, 3UZA, 5OLO, 4UG2, 5IUA, 5OM4, 5NM2, 3REY, 2YDO, 4UHR, 5IU7, 5IUB, 5OM1, 5OLH, 5OLZ, 5NLX, 2YDV, 3RFM, 5MZP, 3PWH, 5IU8, 5OLV
FFAR1 FFA1 2x40 42 TM2 L A thermostabilising 4PHU, 5TZY, 5KW2, 5TZR
S1PR1 S1P1 6x30 251 TM6 S N other-effect 3V2W, 3V2Y
EDNRB ETB 2x56 154 TM2 D A thermostabilising 5X93
C5AR1 C5a1 2x53 85 TM2 S A palmitoylation-site 5O9H
FFAR1 FFA1 3x34 88 TM3 F A thermostabilising 4PHU, 5TZR
EDNRB ETB 8x57 400 H8 C A palmitoylation-site 5X93, 5XPR
NTR1 NTS1 3x49 166 TM3 E A thermostabilising 4GRV, 4XES
NTR1 NTS1 6x40 313 TM6 V M receptor-expression 4BV0
ADRB1 β1 7x53 343 TM7 Y L thermostabilising 4BVN, 5A8E
Q9WTK1 BLT1 309 C-term S A thermostabilising 5X33
NTR1 NTS1 6x37 310 TM6 L A thermostabilising 4GRV
GLP1R GLP-1 6x42 358 TM6 P A thermostabilising 5NX2
AA1R A1 2x52 57 TM2 A L thermostabilising 5N2S
Q9WTK1 BLT1 5x67 212 TM5 V A thermostabilising 5X33
ADRB2 β2 2x66 96 TM2 M T receptor-expression 4GBR, 3SN6, 4QKX, 4LDO, 4LDE, 4LDL, 5JQH
C5AR1 C5a1 4x62 172 TM4 F A palmitoylation-site 5O9H
OPSD Rhodopsin 2 N-term N C thermostabilising, receptor-disulfide-bridge, other-effect 5DGY, 4ZWJ, 5W0P
Q9WTK1 BLT1 3x21 88 TM3 K G thermostabilising 5X33
NTR1 NTS1 2x551 119 TM2 L F receptor-expression 4BWB, 4BV0
EDNRB ETB 405 C-term C A palmitoylation-site 5X93, 5XPR
GLP1R GLP-1 3x32 233 TM3 M C thermostabilising 5VEW, 5VEX
DRD3 D3 3x41 119 TM3 L W thermostabilising 3PBL
CCR9 CCR9 6x36 255 TM6 V A thermostabilising 5LWE
G1SGD4 GLP-1 112 N-term H P other-effect 5VAI
GRM5 mGlu5 675 ICL2 G M thermostabilising 6FFH, 5CGC, 6FFI, 5CGD, 4OO9
CXCR4 CXCR4 45x51 187 ECL2 D C thermostabilising, receptor-ligand-bond 4RWS
CCR5 CCR5 1x60 58 TM1 C Y thermostabilising 5UIW, 4MBS
PAR2 PAR2 6x38 289 TM6 I A thermostabilising 5NJ6, 5NDD, 5NDZ
PAR2 PAR2 1x46 89 TM1 G A thermostabilising 5NJ6, 5NDD, 5NDZ
NTR1 NTS1 5x54 253 TM5 I A thermostabilising 4BUO, 3ZEV, 4BWB, 4BV0
EDNRB ETB 5x36 270 TM5 K A thermostabilising 5X93, 5XPR
G1SGD4 GLP-1 106 N-term T A other-effect 5VAI
NTR1 NTS1 7x25 342 TM7 F A receptor-expression 4BWB, 4BV0
NTR1 NTS1 5x61 260 TM5 I A receptor-expression 4BWB
AA2AR A2A 6x37 235 TM6 L A thermostabilising 5NM4, 5N2R, 3UZC, 5IU4, 5MZJ, 5OLG, 3UZA, 5OLO, 5IUA, 5OM4, 5NM2, 3REY, 5IU7, 5IUB, 5OM1, 5OLH, 5OLZ, 5NLX, 3RFM, 5MZP, 3PWH, 5OLV, 5IU8
ADRB2 β2 3x41 122 TM3 E W receptor-expression, thermostabilising 3NYA, 3NY9, 3NY8, 3D4S
AA1R A1 5x63 205 TM5 Y A thermostabilising 5N2S
DRD2 D2 6x37 375 TM6 L A thermostabilising 6CM4
ACM1 M1 2 N-term N Q glycosylation-site 5CXV
CNR1 CB1 5x37 273 TM5 E K receptor-expression, thermostabilising 5XR8, 5XRA, 5TGZ
ADRB2 β2 23x49 98 ECL1 M T receptor-expression 4GBR, 3SN6, 4QKX, 4LDO, 4LDE, 4LDL, 5JQH
AA1R A1 3x36 91 TM3 T A thermostabilising 5N2S
NTR1 NTS1 1x51 83 TM1 S G receptor-expression 4BWB, 4BV0
OPRD δ 37 N-term P S other-effect 4N6H
AA2AR A2A 2x46 48 TM2 L A thermostabilising 2YDO, 4UG2, 4UHR, 2YDV
ADRB1 β1 3x40 129 TM3 I V thermostabilising 4BVN, 5A8E
APJ apelin 177 ECL2 T N glycosylation-site 5VBL
CXCR4 CXCR4 6x36 240 TM6 T P thermostabilising 3OE0, 3OE9, 4RWS
CRFR1 CRF1 7x38 349 TM7 S A thermostabilising 4K5Y, 4Z9G
S1PR1 S1P1 6x31 252 TM6 L V other-effect 3V2W, 3V2Y
CCR9 CCR9 12x48 77 ICL1 T A thermostabilising 5LWE
NTR1 NTS1 4x65 208 TM4 M V receptor-expression 4BV0
GRM5 mGlu5 5x42 742 TM5 T A thermostabilising 6FFH, 5CGC, 6FFI, 5CGD, 4OO9
GLR glucagon 7x39 387 TM7 F A thermostabilising 5EE7
GRM5 mGlu5 1x35 579 TM1 E A thermostabilising 6FFH, 5CGC, 6FFI, 5CGD, 4OO9
P2Y12 P2Y12 7x49 294 TM7 D N receptor-expression, thermostabilising 4NTJ, 4PY0, 4PXZ
Q9WTK1 BLT1 2x67 83 TM2 H G thermostabilising 5X33
PAR1 PAR1 250 ECL2 N G glycosylation-site 3VW7
APJ apelin 8x60 326 H8 C M palmitoylation-site 5VBL
GLR glucagon 1x48 154 TM1 G A thermostabilising 5EE7
AA2AR A2A 3x39 91 TM3 S A thermostabilising 5WF6
AA2AR A2A 7x41 277 TM7 S A thermostabilising 5NM4, 5N2R, 3UZC, 5IU4, 5MZJ, 5OLG, 3UZA, 5OLO, 5IUA, 5OM4, 5NM2, 3REY, 5IU7, 5IUB, 5OM1, 5OLH, 5OLZ, 5NLX, 3RFM, 5MZP, 3PWH, 5OLV, 5IU8
G1SGD4 GLP-1 1x31 140 TM1 Q R other-effect 5VAI
AA2AR A2A 154 ECL2 N A glycosylation-site 5NM4, 5G53, 5N2R, 5IU4, 5MZJ, 5OLG, 5OLO, 4UG2, 5IUA, 5OM4, 5NM2, 2YDO, 4UHR, 5IU7, 5IUB, 5OM1, 5OLH, 5OLZ, 5NLX, 2YDV, 5MZP, 5IU8, 5OLV
ADRB1 β1 7x48 338 TM7 F M thermostabilising 4AMI, 4GPO, 2YCY, 5A8E, 2Y03, 2YCW, 2Y02, 3ZPR, 3ZPQ, 4AMJ, 5F8U, 2YCZ, 2Y04, 2Y00, 4BVN, 2YCX, 2Y01, 2VT4
GLP1R GLP-1 6x30 346 TM6 K A thermostabilising 5VEW, 5VEX
CCR5 CCR5 8x49 303 H8 K E thermostabilising 5UIW, 4MBS
NTR1 NTS1 3x50 167 TM3 R L receptor-expression 4BUO, 3ZEV, 4BWB, 4BV0
GLR glucagon 4x54 276 TM4 M A thermostabilising 5EE7
ADRB1 β1 6x27 282 TM6 A L thermostabilising 4AMI, 4GPO, 2YCY, 5A8E, 2Y03, 2YCW, 2Y02, 3ZPR, 3ZPQ, 4AMJ, 5F8U, 2YCZ, 2Y04, 2Y00, 4BVN, 2YCX, 2Y01, 2VT4
OPSD Rhodopsin 282 ECL3 D C thermostabilising, receptor-disulfide-bridge 4BEZ, 5DYS, 5EN0, 2X72, 3C9M, 4A4M, 4BEY, 2J4Y
PAR2 PAR2 222 ECL2 N Q glycosylation-site 5NJ6, 5NDD, 5NDZ
C5AR1 C5a1 34x55 146 ICL2 N R palmitoylation-site 5O9H
C5AR1 C5a1 234 ICL3 A E palmitoylation-site 5O9H
PAR2 PAR2 3x34 157 TM3 G A thermostabilising 5NJ6, 5NDD, 5NDZ
GLP1R GLP-1 5x63 329 TM5 C A thermostabilising 5NX2
NTR1 NTS1 2x57 121 TM2 M L receptor-expression 4BWB, 4BV0
GLP1R GLP-1 7x56 405 TM7 V A thermostabilising 5NX2
FFAR1 FFA1 3x49 103 TM3 G A thermostabilising 4PHU, 5TZY, 5KW2, 5TZR
NTR1 NTS1 7x46 362 TM7 S A receptor-expression 4BUO, 3ZEV, 4BWB, 4BV0
OPSD Rhodopsin 18 N-term V I other-effect 2ZIY
CRFR1 CRF1 2x48 160 TM2 S A thermostabilising 4K5Y, 4Z9G
C5AR1 C5a1 321 C-term N E palmitoylation-site 5O9H
ADRB1 β1 7x31 322 TM7 D K thermostabilising 4BVN
GLP1R GLP-1 3x31 232 TM3 L F thermostabilising 5NX2
CRFR1 CRF1 7x53 363 TM7 Y A thermostabilising 4K5Y, 4Z9G
NTR1 NTS1 34x53 177 ICL2 A H receptor-expression 4BV0
ACM2 M2 9 N-term N D glycosylation-site 3UON, 4MQT, 4MQS
OPSD Rhodopsin 2 N-term N C thermostabilising, receptor-disulfide-bridge 4BEZ, 5DYS, 5EN0, 2X72, 3C9M, 4A4M, 4BEY, 2J4Y
DRD2 D2 6x41 379 TM6 L A thermostabilising 6CM4
NTR1 NTS1 5x36 234 TM5 V L receptor-expression 4BUO, 3ZEV, 4BWB, 4BV0
NTR1 NTS1 5x37 235 TM5 K R receptor-expression 4BWB
ACM2 M2 374 ICL3 K R other-effect 4MQT, 4MQS
CRFR1 CRF1 45x52 260 ECL2 F A thermostabilising 4K5Y, 4Z9G
EDNRB ETB 8x53 396 H8 C A palmitoylation-site 5X93, 5XPR
OPSD Rhodopsin 6x40 257 TM6 M Y thermostabilising 4A4M
ADRB2 β2 1x26 27 TM1 E Q other-effect 2R4R, 3NY9, 3D4S, 5D6L, 5D5B, 3NYA, 3NY8, 2RH1, 3KJ6, 2R4S, 3PDS, 3P0G, 5D5A, 5X7D
GLP1R GLP-1 5x51 317 TM5 I C thermostabilising 5VEW, 5VEX
P2RY1 P2Y1 7x49 320 TM7 D N receptor-expression, thermostabilising 4XNV, 4XNW
ADRB1 β1 8x59 358 H8 C A palmitoylation-site 4AMI, 4GPO, 2YCY, 5A8E, 2Y03, 2YCW, 2Y02, 3ZPR, 3ZPQ, 4AMJ, 5F8U, 2YCZ, 2Y04, 2Y00, 4BVN, 2YCX, 2Y01, 2VT4
OPSD Rhodopsin 6x40 257 TM6 M Y thermostabilising 6CMO, 5DGY, 4ZWJ, 5W0P
GLP1R GLP-1 207 ECL1 T E thermostabilising 5NX2
APJ apelin 6x48 261 TM6 W K thermostabilising 5VBL
CCR5 CCR5 6x33 233 TM6 A D thermostabilising, receptor-salt-bridge 5UIW, 4MBS
AA1R A1 7x41 277 TM7 T A thermostabilising 5N2S
NTR1 NTS1 7x43 360 TM7 V A thermostabilising 5T04, 4GRV, 4XEE, 4XES
GLP1R GLP-1 211 ECL1 Q A thermostabilising 5NX2
GLP1R GLP-1 2x59 196 TM2 I F thermostabilising 5VEW, 5VEX
ACM2 M2 6 N-term N D glycosylation-site 3UON, 4MQT, 4MQS
GLP1R GLP-1 6x31 347 TM6 C F thermostabilising 5VEW, 5VEX
CRFR1 CRF1 2x44 156 TM2 W A thermostabilising 4K5Y, 4Z9G
ACM2 M2 3 N-term N D glycosylation-site 3UON, 4MQT, 4MQS
NTR1 NTS1 3x44 161 TM3 A V receptor-expression 4BUO, 3ZEV, 4BWB, 4BV0
EDNRB ETB 6x54 342 TM6 S A thermostabilising 5X93, 5XPR
GLR glucagon 6x30 344 TM6 K A thermostabilising 5EE7
AA2AR A2A 2x62 65 TM2 T A thermostabilising 2YDO, 4UG2, 4UHR, 2YDV
SMO SMO 3x40 329 TM3 V F receptor-expression, thermostabilising 5L7D, 5L7I
OPSD Rhodopsin 3x28 113 TM3 E Q thermostabilising 6CMO, 5DGY, 4ZWJ, 5W0P
PAR2 PAR2 6x42 293 TM6 L A thermostabilising 5NJ6, 5NDD, 5NDZ
GRM5 mGlu5 3x50 669 TM3 I A thermostabilising 6FFH, 5CGC, 6FFI, 5CGD, 4OO9
OPRK κ 3x29 135 TM3 I L receptor-expression 4DJH, 6B73
ACM1 M1 3x37 110 TM3 N Q glycosylation-site 5CXV
NTR1 NTS1 3x33 150 TM3 D E receptor-expression 4BWB, 4BV0
OX1R OX1 6x56 319 TM6 V I other-effect 4ZJ8, 4ZJC
NTR1 NTS1 215 ECL2 G A thermostabilising 5T04, 4GRV, 4XEE, 4XES
C5AR1 C5a1 4x45 156 TM4 A L palmitoylation-site 5O9H
NTR1 NTS1 2x38 101 TM2 T R receptor-expression 4BWB, 4BV0
CRFR1 CRF1 1x60 144 TM1 L A thermostabilising 4K5Y, 4Z9G
DRD2 D2 3x40 122 TM3 I A thermostabilising 6CM4
CRFR1 CRF1 4x43 228 TM4 K A thermostabilising 4K5Y, 4Z9G
NTR1 NTS1 3x26 143 TM3 R K receptor-expression 4BWB, 4BV0
CRFR1 CRF1 1x36 120 TM1 V A thermostabilising 4K5Y, 4Z9G
AA2AR A2A 6x41 239 TM6 V A thermostabilising 5NM4, 5N2R, 3UZC, 5IU4, 5MZJ, 5OLG, 3UZA, 5OLO, 5IUA, 5OM4, 5NM2, 3REY, 5IU7, 5IUB, 5OM1, 5OLH, 5OLZ, 5NLX, 3RFM, 5MZP, 3PWH, 5OLV, 5IU8