Mutations

Position
NTR1 NTS1 2x551 119 TM2 L F receptor-expression 4BV0, 4BWB
AA1R A1 8x64 309 H8 C S palmitoylation-site 5N2S
OPSD Rhodopsin 2 N-term N C receptor-disulfide-bridge, thermostabilising 3C9M, 5EN0, 4BEY, 2J4Y, 2X72, 4A4M, 4BEZ, 5DYS
5HT2C 5-HT2C 7x45 360 TM7 C N receptor-expression, thermostabilising 6BQH, 6BQG
SMO SMO 3x40 329 TM3 V F receptor-expression, thermostabilising 5L7I, 5L7D
NTR1 NTS1 7x43 360 TM7 V A thermostabilising 4XEE, 4XES, 5T04, 4GRV
AA2AR A2A 6x37 235 TM6 L A thermostabilising 5NM4, 3PWH, 3UZC, 5OLV, 5IU4, 5IUB, 3UZA, 3REY, 5OLH, 5OLZ, 5NM2, 5OM1, 5MZJ, 5OLO, 5OLG, 5OM4, 5IU8, 5MZP, 5NLX, 5IU7, 5N2R, 3RFM, 5IUA
GLP1R GLP-1 3x24 225 TM3 S A thermostabilising 5VEX, 5VEW
NTR1 NTS1 5x36 234 TM5 V L receptor-expression 4BUO, 4BV0, 3ZEV, 4BWB
AA2AR A2A 154 ECL2 N Q glycosylation-site 3VG9, 3VGA
CRFR1 CRF1 45x52 260 ECL2 F A thermostabilising 4Z9G, 4K5Y
AA1R A1 2x52 57 TM2 A L thermostabilising 5N2S
CCR9 CCR9 3x47 141 TM3 S C thermostabilising 5LWE
ACM2 M2 9 N-term N D glycosylation-site 4MQS, 3UON, 4MQT
GLP1R GLP-1 45x52 298 ECL2 T A thermostabilising 5NX2
GLP1R GLP-1 207 ECL1 T E thermostabilising 5NX2
NTR1 NTS1 213 ECL2 R L receptor-expression 4BUO, 4BV0, 3ZEV, 4BWB
NTR1 NTS1 5x61 260 TM5 I A receptor-expression 4BWB
CCR5 CCR5 4x61 163 TM4 G N thermostabilising 5UIW, 4MBS
GRM5 mGlu5 1x35 579 TM1 E A thermostabilising 6FFH, 6FFI, 5CGC, 5CGD, 4OO9
GLP1R GLP-1 2x59 196 TM2 I F thermostabilising 5VEX, 5VEW
ADRB2 β2 6x27 265 TM6 C A other-effect 4QKX, 4LDL, 4LDE, 5JQH, 4LDO
NTR1 NTS1 2x61 125 TM2 L V receptor-expression 4BV0
CXCR4 CXCR4 6x36 240 TM6 T P thermostabilising 3OE9, 3OE0, 4RWS
CCR9 CCR9 7x29 294 TM7 N A thermostabilising 5LWE
NTR1 NTS1 2x42 105 TM2 H Y receptor-expression 4BUO, 4BV0, 3ZEV, 4BWB
ADRB2 β2 2x66 96 TM2 M T receptor-expression 3SN6, 4GBR, 4LDE, 5JQH, 4QKX, 4LDL, 4LDO
PAR1 PAR1 250 ECL2 N G glycosylation-site 3VW7
ACM2 M2 3 N-term N D glycosylation-site 4MQS, 3UON, 4MQT
GLP1R GLP-1 3x32 233 TM3 M C thermostabilising 5VEX, 5VEW
GLP1R GLP-1 6x42 358 TM6 P A thermostabilising 5NX2
EDNRB ETB 7x48 381 TM7 I A thermostabilising 5X93, 5XPR
FFAR1 FFA1 2x40 42 TM2 L A thermostabilising 4PHU, 5TZY, 5TZR, 5KW2
CCR9 CCR9 34 N-term T E glycosylation-site 5LWE
OPSD Rhodopsin 2x60 94 TM2 T I thermostabilising 5EN0, 5DYS
ADRB1 β1 8x59 358 H8 C A palmitoylation-site 2YCY, 3ZPQ, 4BVN, 3ZPR, 2YCX, 2Y00, 2Y04, 2Y01, 5F8U, 2Y03, 5A8E, 4AMJ, 4AMI, 2YCW, 2Y02, 4GPO, 2YCZ, 2VT4
NTR1 NTS1 3x44 161 TM3 A V receptor-expression 4BUO, 4BV0, 3ZEV, 4BWB
GLR glucagon 3x24 223 TM3 G A thermostabilising 5EE7
NTR1 NTS1 6x59 332 TM6 C V receptor-expression 4BV0, 4BWB
PAR2 PAR2 5x64 268 TM5 M A thermostabilising 5NJ6, 5NDZ, 5NDD
CRFR1 CRF1 4x43 228 TM4 K A thermostabilising 4Z9G, 4K5Y
NTR1 NTS1 7x41 358 TM7 F V receptor-expression 4BUO, 4BV0, 3ZEV, 4BWB
GLP1R GLP-1 6x45 361 TM6 G C thermostabilising 5VEX, 5VEW
GLR glucagon 7x39 387 TM7 F A thermostabilising 5EE7
NTR1 NTS1 3x33 150 TM3 D E receptor-expression 4BV0, 4BWB
CCR9 CCR9 6x36 255 TM6 V A thermostabilising 5LWE
OPRD δ 37 N-term P S other-effect 4N6H
DRD2 D2 3x40 122 TM3 I A thermostabilising 6CM4
OPSD Rhodopsin 6x40 257 TM6 M Y thermostabilising 4ZWJ, 5W0P, 5DGY, 6CMO
APJ apelin 6x48 261 TM6 W K thermostabilising 5VBL
ACM1 M1 3x37 110 TM3 N Q glycosylation-site 5CXV
APJ apelin 177 ECL2 T N glycosylation-site 5VBL
AA1R A1 7x41 277 TM7 T A thermostabilising 5N2S
GRM5 mGlu5 5x42 742 TM5 T A thermostabilising 6FFH, 6FFI, 5CGC, 5CGD, 4OO9
NTR1 NTS1 2x38 101 TM2 T R receptor-expression 4BV0, 4BWB
CNR1 CB1 3x46 210 TM3 T A thermostabilising 5TGZ, 5XR8, 5XRA, 5U09
G1SGD4 GLP-1 1x31 140 TM1 Q R other-effect 5VAI
OPSD Rhodopsin 2 N-term N C receptor-disulfide-bridge, other-effect, thermostabilising 4ZWJ, 5W0P, 5DGY
ADRB2 β2 3x41 122 TM3 E W receptor-expression, thermostabilising 3D4S, 3NY9, 3NY8, 3NYA
NTR1 NTS1 2x40 103 TM2 H D receptor-expression 4BUO, 4BV0, 3ZEV, 4BWB
C5AR1 C5a1 34x51 142 ICL2 I A palmitoylation-site 5O9H
GLR glucagon 1x48 154 TM1 G A thermostabilising 5EE7
CNR1 CB1 6x32 340 TM6 R E receptor-expression, thermostabilising 5TGZ, 5XR8, 5XRA
GLR glucagon 2x59 193 TM2 V F thermostabilising 5EE7
P2RY1 P2Y1 7x49 320 TM7 D N receptor-expression, thermostabilising 4XNW, 4XNV
NTR1 NTS1 5x42 240 TM5 V L receptor-expression 4BV0, 4BWB
CCR9 CCR9 12x48 77 ICL1 T A thermostabilising 5LWE
ADRB1 β1 1x59 68 TM1 R S thermostabilising 2YCY, 3ZPQ, 4BVN, 3ZPR, 2YCX, 2Y00, 2Y04, 2Y01, 5F8U, 2Y03, 5A8E, 4AMJ, 4AMI, 2YCW, 2Y02, 4GPO, 2YCZ, 2VT4
PAR2 PAR2 3x53 176 TM3 V E thermostabilising 5NJ6, 5NDZ, 5NDD
CCR9 CCR9 8x63 337 H8 C A palmitoylation-site 5LWE
AA2AR A2A 5x63 202 TM5 L A thermostabilising 5NM4, 3PWH, 3UZC, 5OLV, 5IU4, 5IUB, 3UZA, 3REY, 5OLH, 5OLZ, 5NM2, 5OM1, 5MZJ, 5OLO, 5OLG, 5OM4, 5IU8, 5MZP, 5NLX, 5IU7, 5N2R, 3RFM, 5IUA
NTR1 NTS1 3x26 143 TM3 R K receptor-expression 4BV0, 4BWB
CNR1 CB1 5x47 283 TM5 T V receptor-expression 5TGZ, 5XR8, 5XRA
CRFR1 CRF1 7x53 363 TM7 Y A thermostabilising 4Z9G, 4K5Y
AA1R A1 3x36 91 TM3 T A thermostabilising 5N2S
GLP1R GLP-1 6x30 346 TM6 K A thermostabilising 5VEX, 5VEW
S1PR1 S1P1 6x31 252 TM6 L V other-effect 3V2Y, 3V2W
PAR2 PAR2 3x34 157 TM3 G A thermostabilising 5NJ6, 5NDZ, 5NDD
NTR1 NTS1 34x53 177 ICL2 A H receptor-expression 4BV0
OX2R OX2 6x39 308 TM6 I V other-effect 5WS3, 5WQC, 4S0V
APJ apelin 8x60 326 H8 C M palmitoylation-site 5VBL
GLP1R GLP-1 6x31 347 TM6 C F thermostabilising 5VEX, 5VEW
EDNRB ETB 8x57 400 H8 C A palmitoylation-site 5X93, 5XPR
CCR9 CCR9 2x38 82 TM2 M A thermostabilising 5LWE
ADRB2 β2 23x49 98 ECL1 M T receptor-expression 3SN6, 4GBR, 4LDE, 5JQH, 4QKX, 4LDL, 4LDO
GLR glucagon 2x48 182 TM2 A L thermostabilising 5EE7
C5AR1 C5a1 317 C-term S E palmitoylation-site 5O9H
CCR9 CCR9 5x41 216 TM5 T A thermostabilising 5LWE
CNR1 CB1 5x37 273 TM5 E K receptor-expression, thermostabilising 5TGZ, 5XR8, 5XRA
ADRB1 β1 7x36 327 TM7 F A thermostabilising 2YCY, 3ZPQ, 4BVN, 3ZPR, 2YCX, 2Y00, 2Y04, 2Y01, 5F8U, 2Y03, 5A8E, 4AMJ, 4AMI, 2YCW, 2Y02, 4GPO, 2YCZ, 2VT4
FFAR1 FFA1 3x49 103 TM3 G A thermostabilising 4PHU, 5TZY, 5TZR, 5KW2
ADRB2 β2 16 N-term G R other-effect 3NYA, 3D4S, 3NY9, 3NY8, 3KJ6, 2RH1, 5X7D, 5D5B, 3P0G, 5D6L, 2R4R, 5D5A
AA1R A1 6x37 236 TM6 L A thermostabilising 5N2S
NTR1 NTS1 6x32 305 TM6 H R receptor-expression 4BUO, 4BV0, 3ZEV, 4BWB
ADRB1 β1 3x40 129 TM3 I V thermostabilising 4BVN, 5A8E
PAR1 PAR1 259 ECL2 N S glycosylation-site 3VW7
OPRK κ 3x29 135 TM3 I L receptor-expression 4DJH, 6B73
CRFR1 CRF1 2x48 160 TM2 S A thermostabilising 4Z9G, 4K5Y
AA2AR A2A 3x36 88 TM3 T A thermostabilising 5NM4, 3PWH, 3UZC, 5OLV, 5IU4, 5IUB, 3UZA, 3REY, 5OLH, 5OLZ, 5NM2, 5OM1, 5MZJ, 5OLO, 5OLG, 5OM4, 5IU8, 5MZP, 5NLX, 5IU7, 5N2R, 3RFM, 5IUA
AA2AR A2A 2x52 54 TM2 A L thermostabilising 5NM4, 3PWH, 3UZC, 5OLV, 5IU4, 5IUB, 4UHR, 3UZA, 3REY, 5OLH, 5OLZ, 2YDV, 4UG2, 5NM2, 5OM1, 2YDO, 5MZJ, 5OLO, 5OLG, 5OM4, 5IU8, 5MZP, 5NLX, 5IU7, 5N2R, 3RFM, 5IUA
GLP1R GLP-1 3x31 232 TM3 L F thermostabilising 5NX2
OPSD Rhodopsin 338 C-term S X phosphorylation-site 5W0P
CRFR1 CRF1 7x38 349 TM7 S A thermostabilising 4Z9G, 4K5Y
P2Y12 P2Y12 7x49 294 TM7 D N receptor-expression, thermostabilising 4NTJ, 4PXZ, 4PY0
CRFR1 CRF1 6x51 330 TM6 F A thermostabilising 4Z9G, 4K5Y
AA1R A1 5x63 205 TM5 Y A thermostabilising 5N2S
ADRB1 β1 3x27 116 TM3 C L receptor-expression 2YCY, 3ZPQ, 4BVN, 3ZPR, 2YCX, 2Y00, 2Y04, 2Y01, 5F8U, 2Y03, 5A8E, 4AMJ, 4AMI, 2YCW, 2Y02, 4GPO, 2YCZ, 2VT4
GLP1R GLP-1 7x56 405 TM7 V A thermostabilising 5NX2
NTR1 NTS1 7x25 342 TM7 F A receptor-expression 4BV0, 4BWB
ACM2 M2 374 ICL3 K R other-effect 4MQS, 4MQT
GLP1R GLP-1 211 ECL1 Q A thermostabilising 5NX2
GLP1R GLP-1 295 ECL2 G A thermostabilising 5NX2
AA2AR A2A 6x41 239 TM6 V A thermostabilising 5NM4, 3PWH, 3UZC, 5OLV, 5IU4, 5IUB, 3UZA, 3REY, 5OLH, 5OLZ, 5NM2, 5OM1, 5MZJ, 5OLO, 5OLG, 5OM4, 5IU8, 5MZP, 5NLX, 5IU7, 5N2R, 3RFM, 5IUA
Q9WTK1 BLT1 2x67 83 TM2 H G thermostabilising 5X33
ADRB1 β1 7x48 338 TM7 F M thermostabilising 2YCY, 3ZPQ, 4BVN, 3ZPR, 2YCX, 2Y00, 2Y04, 2Y01, 5F8U, 2Y03, 5A8E, 4AMJ, 4AMI, 2YCW, 2Y02, 4GPO, 2YCZ, 2VT4
OPSD Rhodopsin 336 C-term T X phosphorylation-site 5W0P
CXCR4 CXCR4 3x41 125 TM3 L W thermostabilising 3ODU, 3OE8, 3OE9, 3OE0, 4RWS, 3OE6
GLR glucagon 6x48 362 TM6 E F thermostabilising 5EE7
GLP1R GLP-1 5x51 317 TM5 I C thermostabilising 5VEX, 5VEW
CRFR1 CRF1 5x48 277 TM5 I A thermostabilising 4Z9G, 4K5Y
C5AR1 C5a1 321 C-term N E palmitoylation-site 5O9H
PAR2 PAR2 6x42 293 TM6 L A thermostabilising 5NJ6, 5NDZ, 5NDD
EDNRB ETB 5x36 270 TM5 K A thermostabilising 5X93, 5XPR
AA2AR A2A 2x50 52 TM2 D N thermostabilising 5WF5
AA2AR A2A 3x55 107 TM3 R A thermostabilising 5NM4, 3PWH, 3UZC, 5OLV, 5IU4, 5IUB, 3UZA, 3REY, 5OLH, 5OLZ, 5NM2, 5OM1, 5MZJ, 5OLO, 5OLG, 5OM4, 5IU8, 5MZP, 5NLX, 5IU7, 5N2R, 3RFM, 5IUA
C5AR1 C5a1 4x45 156 TM4 A L palmitoylation-site 5O9H
C5AR1 C5a1 2x59 91 TM2 I A palmitoylation-site 5O9H
NTR1 NTS1 5x64 263 TM5 K R receptor-expression 4BV0, 4BWB
CCR9 CCR9 7x39 304 TM7 T A thermostabilising 5LWE
OPSD Rhodopsin 282 ECL3 N C receptor-disulfide-bridge, thermostabilising 4ZWJ, 5W0P, 5DGY, 6CMO
S1PR1 S1P1 6x30 251 TM6 S N other-effect 3V2Y, 3V2W
NTR1 NTS1 4x65 208 TM4 M V receptor-expression 4BV0
GRM5 mGlu5 3x48 667 TM3 N Y thermostabilising 6FFH, 6FFI, 5CGC, 5CGD, 4OO9
GLR glucagon 2x39 173 TM2 R A thermostabilising 5EE7, 5YQZ
OPSD Rhodopsin 2x56 90 TM2 G D natural-mutation-snp-incl-disease-causing 4BEY, 4BEZ
C5AR1 C5a1 2x53 85 TM2 S A palmitoylation-site 5O9H
ACM2 M2 2 N-term N D glycosylation-site 4MQS, 3UON, 4MQT
ADRB1 β1 7x53 343 TM7 Y L thermostabilising 4BVN, 5A8E
NTR1 NTS1 5x63 262 TM5 N R receptor-expression 4BV0, 4BWB
ADRB1 β1 6x27 282 TM6 A L thermostabilising 2YCY, 3ZPQ, 4BVN, 3ZPR, 2YCX, 2Y00, 2Y04, 2Y01, 5F8U, 2Y03, 5A8E, 4AMJ, 4AMI, 2YCW, 2Y02, 4GPO, 2YCZ, 2VT4
PAR2 PAR2 222 ECL2 N Q glycosylation-site 5NJ6, 5NDZ, 5NDD
C5AR1 C5a1 8x54 311 H8 L E palmitoylation-site 5O9H
CCR5 CCR5 6x33 233 TM6 A D receptor-salt-bridge, thermostabilising 5UIW, 4MBS
NTR1 NTS1 5x54 253 TM5 I A thermostabilising 4BUO, 4BV0, 3ZEV, 4BWB
GLR glucagon 207 ECL1 G E thermostabilising 5EE7
NTR1 NTS1 5x37 235 TM5 K R receptor-expression 4BWB
5HT1B 5-HT1B 3x41 138 TM3 L W thermostabilising 5V54, 4IAR, 4IAQ, 6G79
C5AR1 C5a1 4x62 172 TM4 F A palmitoylation-site 5O9H
OPSD Rhodopsin 18 N-term V I other-effect 2ZIY
ACM2 M2 6 N-term N D glycosylation-site 4MQS, 3UON, 4MQT
LPAR1 LPA1 5x37 204 TM5 D C receptor-disulfide-bridge, thermostabilising 4Z36
C5AR1 C5a1 5x68 232 TM5 R A palmitoylation-site 5O9H
FFAR1 FFA1 3x34 88 TM3 F A thermostabilising 4PHU, 5TZR
NTR1 NTS1 7x46 362 TM7 S A receptor-expression 4BUO, 4BV0, 3ZEV, 4BWB
GLR glucagon 2x56 190 TM2 S A thermostabilising 5EE7
NTR1 NTS1 7x41 358 TM7 F A receptor-expression 5T04, 4GRV
ADRB1 β1 2x53 90 TM2 M V thermostabilising 2YCY, 3ZPQ, 4BVN, 3ZPR, 2YCX, 2Y00, 2Y04, 2Y01, 5F8U, 2Y03, 5A8E, 4AMJ, 4AMI, 2YCW, 2Y02, 4GPO, 2YCZ, 2VT4
CCR9 CCR9 12x50 79 ICL1 V A thermostabilising 5LWE
GRM5 mGlu5 5x53 753 TM5 S A thermostabilising 6FFH, 6FFI, 5CGC, 5CGD, 4OO9
NTR1 NTS1 2x60 124 TM2 E D receptor-expression 4BV0, 4BWB
NTR1 NTS1 215 ECL2 G A thermostabilising 4XEE, 4XES, 5T04, 4GRV
OPSD Rhodopsin 282 ECL3 D C receptor-disulfide-bridge, thermostabilising 3C9M, 5EN0, 4BEY, 2J4Y, 2X72, 4A4M, 4BEZ, 5DYS
5HT2B 5-HT2B 3x41 144 TM3 M W thermostabilising 4IB4, 5TVN, 5TUD, 4NC3
APJ apelin 3x40 117 TM3 V A thermostabilising 5VBL
AA1R A1 159 ECL2 N A glycosylation-site 5N2S, 5UEN
GLP1R GLP-1 215 ECL1 D R thermostabilising 5NX2
Q9WTK1 BLT1 5x67 212 TM5 V A thermostabilising 5X33
G1SGD4 GLP-1 106 N-term T A other-effect 5VAI
ACM1 M1 12 N-term N Q glycosylation-site 5CXV
C5AR1 C5a1 34x55 146 ICL2 N R palmitoylation-site 5O9H
CRFR1 CRF1 6x30 309 TM6 Y A thermostabilising 4Z9G, 4K5Y
NTR1 NTS1 7x37 354 TM7 T S receptor-expression 4BV0, 4BWB
NTR1 NTS1 1x54 86 TM1 A L thermostabilising 4BUO, 3ZEV, 4XES, 4BV0, 4GRV, 4BWB, 4XEE, 5T04
Q9WTK1 BLT1 309 C-term S A thermostabilising 5X33
C5AR1 C5a1 234 ICL3 A E palmitoylation-site 5O9H
EDNRB ETB 8x53 396 H8 C A palmitoylation-site 5X93, 5XPR
Q9WTK1 BLT1 3x21 88 TM3 K G thermostabilising 5X33
NTR1 NTS1 2x57 121 TM2 M L receptor-expression 4BV0, 4BWB
GLP1R GLP-1 6x45 361 TM6 G A thermostabilising 5NX2
NTR1 NTS1 3x49 166 TM3 E A thermostabilising 4XES, 4GRV
ADRB1 β1 7x31 322 TM7 D K thermostabilising 4BVN
G1SGD4 GLP-1 112 N-term H P other-effect 5VAI
NTR1 NTS1 3x55 172 TM3 C R receptor-expression 4BV0
PAR2 PAR2 1x46 89 TM1 G A thermostabilising 5NJ6, 5NDZ, 5NDD
GLP1R GLP-1 2x56 193 TM2 S C thermostabilising 5VEX, 5VEW
DRD2 D2 6x37 375 TM6 L A thermostabilising 6CM4
ADRB2 β2 2x63 93 TM2 H C thermostabilising, receptor-ligand-bond 3PDS, 4QKX
AA2AR A2A 4x43 122 TM4 K A thermostabilising 5NM4, 3PWH, 3UZC, 5OLV, 5IU4, 5IUB, 3UZA, 3REY, 5OLH, 5OLZ, 5NM2, 5OM1, 5MZJ, 5OLO, 5OLG, 5OM4, 5IU8, 5MZP, 5NLX, 5IU7, 5N2R, 3RFM, 5IUA
CRFR1 CRF1 1x36 120 TM1 V A thermostabilising 4Z9G, 4K5Y
EDNRB ETB 2x56 154 TM2 D A thermostabilising 5X93
GLP1R GLP-1 6x47 363 TM6 H V thermostabilising 5NX2
ACM1 M1 2 N-term N Q glycosylation-site 5CXV
ADRB1 β1 5x58 227 TM5 Y A thermostabilising 2YCY, 3ZPQ, 4BVN, 3ZPR, 2YCX, 2Y00, 2Y04, 2Y01, 5F8U, 2Y03, 5A8E, 4AMJ, 4AMI, 2YCW, 2Y02, 4GPO, 2YCZ, 2VT4
EDNRB ETB 1x55 124 TM1 R Y thermostabilising 5X93, 5XPR
ADRB2 β2 1x26 27 TM1 E Q other-effect 3NYA, 3D4S, 3NY9, 3NY8, 3KJ6, 3PDS, 2R4S, 2RH1, 5X7D, 5D5B, 3P0G, 5D6L, 2R4R, 5D5A
ACM2 M2 373 ICL3 A T other-effect 4MQS, 4MQT
PAR2 PAR2 2x37 108 TM2 H A thermostabilising 5NJ6, 5NDZ, 5NDD
AA2AR A2A 154 ECL2 N A glycosylation-site 5NM4, 5OLV, 5IU4, 5IUB, 4UHR, 5G53, 5OLH, 5OLZ, 2YDV, 4UG2, 5NM2, 5OM1, 2YDO, 5MZJ, 5OLO, 5OLG, 5OM4, 5IU8, 5MZP, 5NLX, 5IU7, 5N2R, 5IUA
PAR2 PAR2 3x43 166 TM3 M L thermostabilising 5NJ6, 5NDZ, 5NDD
GRM5 mGlu5 3x50 669 TM3 I A thermostabilising 6FFH, 6FFI, 5CGC, 5CGD, 4OO9
AA2AR A2A 3x37 89 TM3 Q A thermostabilising 2YDO, 4UHR, 2YDV, 4UG2
NTR1 NTS1 6x40 313 TM6 V M receptor-expression 4BV0
GLP1R GLP-1 5x63 329 TM5 C A thermostabilising 5NX2
ADRB2 β2 187 ECL2 N E glycosylation-site 5D5A, 3NYA, 3SN6, 3NY9, 3D4S, 3NY8, 3KJ6, 4GBR, 3PDS, 4LDE, 5JQH, 2RH1, 5X7D, 5D5B, 4QKX, 3P0G, 4LDL, 5D6L, 4LDO
GLP1R GLP-1 5x52 318 TM5 G I thermostabilising 5VEX, 5VEW
OPSD Rhodopsin 3x28 113 TM3 E Q thermostabilising 2X72
AA2AR A2A 2x62 65 TM2 T A thermostabilising 2YDO, 4UHR, 2YDV, 4UG2
APJ apelin 8x59 325 H8 C L palmitoylation-site 5VBL
GLR glucagon 6x30 344 TM6 K A thermostabilising 5EE7
NTR1 NTS1 3x50 167 TM3 R L receptor-expression 4BUO, 4BV0, 3ZEV, 4BWB
CXCR4 CXCR4 45x51 187 ECL2 D C thermostabilising, receptor-ligand-bond 4RWS
PAR2 PAR2 3x51 174 TM3 Y A thermostabilising 5NJ6, 5NDZ, 5NDD
OPSD Rhodopsin 3x28 113 TM3 E Q thermostabilising 4ZWJ, 5W0P, 5DGY, 6CMO
CCR5 CCR5 8x49 303 H8 K E thermostabilising 5UIW, 4MBS
AA1R A1 6x41 240 TM6 L A thermostabilising 5N2S
DRD3 D3 3x41 119 TM3 L W thermostabilising 3PBL
CRFR1 CRF1 2x44 156 TM2 W A thermostabilising 4Z9G, 4K5Y
GRM5 mGlu5 675 ICL2 G M thermostabilising 6FFH, 6FFI, 5CGC, 5CGD, 4OO9
GLP1R GLP-1 4x48 271 TM4 S A thermostabilising 5VEX, 5VEW
AA2AR A2A 3x39 91 TM3 S A thermostabilising 5WF6
NTR1 NTS1 6x37 310 TM6 L A thermostabilising 4GRV
LPAR1 LPA1 6x59 282 TM6 V C receptor-disulfide-bridge, thermostabilising 4Z36
CRFR1 CRF1 1x60 144 TM1 L A thermostabilising 4Z9G, 4K5Y
OX1R OX1 6x56 319 TM6 V I other-effect 4ZJC, 4ZJ8
NTR1 NTS1 1x51 83 TM1 S G receptor-expression 4BV0, 4BWB
ADRB1 β1 3x41 130 TM3 E W thermostabilising 5A8E
PAR2 PAR2 6x38 289 TM6 I A thermostabilising 5NJ6, 5NDZ, 5NDD
AA2AR A2A 2x46 48 TM2 L A thermostabilising 2YDO, 4UHR, 2YDV, 4UG2
GLR glucagon 4x54 276 TM4 M A thermostabilising 5EE7
FFAR1 FFA1 5x58 202 TM5 Y F thermostabilising 4PHU, 5TZY, 5TZR, 5KW2
DRD2 D2 6x41 379 TM6 L A thermostabilising 6CM4
EDNRB ETB 405 C-term C A palmitoylation-site 5X93, 5XPR
CCR5 CCR5 1x60 58 TM1 C Y thermostabilising 5UIW, 4MBS
GLP1R GLP-1 260 ICL2 L F other-effect, thermostabilising 5NX2
OPSD Rhodopsin 6x40 257 TM6 M Y thermostabilising 4A4M
EDNRB ETB 6x54 342 TM6 S A thermostabilising 5X93, 5XPR
AA2AR A2A 7x41 277 TM7 S A thermostabilising 5NM4, 3PWH, 3UZC, 5OLV, 5IU4, 5IUB, 3UZA, 3REY, 5OLH, 5OLZ, 5NM2, 5OM1, 5MZJ, 5OLO, 5OLG, 5OM4, 5IU8, 5MZP, 5NLX, 5IU7, 5N2R, 3RFM, 5IUA