Mutations

Position
CRFR1 CRF1 1x36 120 TM1 V A thermostabilising 4Z9G, 4K5Y
ADRB1 β1 7x36 327 TM7 F A thermostabilising 2YCW, 2Y01, 2Y04, 2Y00, 2YCY, 2Y02, 5F8U, 3ZPR, 3ZPQ, 2YCX, 4BVN, 5A8E, 2YCZ, 2Y03, 4AMI, 4GPO, 4AMJ, 2VT4
EDNRB ETB 2x56 154 TM2 D A thermostabilising 5X93
GLP1R GLP-1 3x31 232 TM3 L F thermostabilising 5NX2
5HT2B 5-HT2B 3x41 144 TM3 M W thermostabilising 4IB4, 5TVN, 5TUD, 4NC3
NTR1 NTS1 1x54 86 TM1 A L thermostabilising 3ZEV, 4XEE, 4GRV, 4XES, 5T04, 4BWB, 4BV0, 4BUO
GRM5 mGlu5 1x35 579 TM1 E A thermostabilising 4OO9, 6FFH, 6FFI, 5CGD, 5CGC
GLP1R GLP-1 5x63 329 TM5 C A thermostabilising 5NX2
NTR1 NTS1 3x44 161 TM3 A V receptor-expression 4BWB, 4BV0, 3ZEV, 4BUO
C5AR1 C5a1 2x53 85 TM2 S A palmitoylation-site 5O9H
CCR5 CCR5 4x61 163 TM4 G N thermostabilising 5UIW, 4MBS
NTR1 NTS1 3x49 166 TM3 E A thermostabilising 4GRV, 4XES
ADRB2 β2 1x26 27 TM1 E Q other-effect 3NY8, 3P0G, 5D6L, 3PDS, 5D5A, 3NY9, 3NYA, 5X7D, 2RH1, 3D4S, 2R4R, 2R4S, 3KJ6, 5D5B
GRM5 mGlu5 3x50 669 TM3 I A thermostabilising 4OO9, 6FFH, 6FFI, 5CGD, 5CGC
OX1R OX1 6x56 319 TM6 V I other-effect 4ZJ8, 4ZJC
NTR1 NTS1 34x53 177 ICL2 A H receptor-expression 4BV0
ADRB1 β1 3x41 130 TM3 E W thermostabilising 5A8E
5HT2C 5-HT2C 7x45 360 TM7 C N receptor-expression, thermostabilising 6BQG, 6BQH
AA2AR A2A 154 ECL2 N Q glycosylation-site 3VG9, 3VGA
CRFR1 CRF1 2x44 156 TM2 W A thermostabilising 4Z9G, 4K5Y
ADRB1 β1 7x31 322 TM7 D K thermostabilising 4BVN
EDNRB ETB 8x53 396 H8 C A palmitoylation-site 5XPR, 5X93
ADRB2 β2 23x49 98 ECL1 M T receptor-expression 5JQH, 4GBR, 4QKX, 4LDO, 3SN6, 4LDE, 4LDL
NTR1 NTS1 4x65 208 TM4 M V receptor-expression 4BV0
Q9WTK1 BLT1 309 C-term S A thermostabilising 5X33
AA2AR A2A 6x41 239 TM6 V A thermostabilising 5OLG, 5OLO, 5MZJ, 5OLZ, 5OLV, 5IU7, 3UZA, 5OM4, 5NM2, 5NM4, 3REY, 5OLH, 5NLX, 5IUA, 5IUB, 3UZC, 5IU8, 5MZP, 5IU4, 3PWH, 3RFM, 5OM1, 5N2R
FFAR1 FFA1 3x34 88 TM3 F A thermostabilising 4PHU, 5TZR
AA2AR A2A 4x43 122 TM4 K A thermostabilising 5OLG, 5OLO, 5MZJ, 5OLZ, 5OLV, 5IU7, 3UZA, 5OM4, 5NM2, 5NM4, 3REY, 5OLH, 5NLX, 5IUA, 5IUB, 3UZC, 5IU8, 5MZP, 5IU4, 3PWH, 3RFM, 5OM1, 5N2R
NTR1 NTS1 5x37 235 TM5 K R receptor-expression 4BWB
ADRB1 β1 8x59 358 H8 C A palmitoylation-site 2YCW, 2Y01, 2Y04, 2Y00, 2YCY, 2Y02, 5F8U, 3ZPR, 3ZPQ, 2YCX, 4BVN, 5A8E, 2YCZ, 2Y03, 4AMI, 4GPO, 4AMJ, 2VT4
ADRB1 β1 5x58 227 TM5 Y A thermostabilising 2YCW, 2Y01, 2Y04, 2Y00, 2YCY, 2Y02, 5F8U, 3ZPR, 3ZPQ, 2YCX, 4BVN, 5A8E, 2YCZ, 2Y03, 4AMI, 4GPO, 4AMJ, 2VT4
ADRB1 β1 3x27 116 TM3 C L receptor-expression 2YCW, 2Y01, 2Y04, 2Y00, 2YCY, 2Y02, 5F8U, 3ZPR, 3ZPQ, 2YCX, 4BVN, 5A8E, 2YCZ, 2Y03, 4AMI, 4GPO, 4AMJ, 2VT4
C5AR1 C5a1 34x55 146 ICL2 N R palmitoylation-site 5O9H
PAR2 PAR2 2x37 108 TM2 H A thermostabilising 5NDD, 5NDZ, 5NJ6
CCR5 CCR5 1x60 58 TM1 C Y thermostabilising 5UIW, 4MBS
CRFR1 CRF1 7x53 363 TM7 Y A thermostabilising 4Z9G, 4K5Y
AA1R A1 5x63 205 TM5 Y A thermostabilising 5N2S
OPRD δ 37 N-term P S other-effect 4N6H
FFAR1 FFA1 2x40 42 TM2 L A thermostabilising 4PHU, 5TZR, 5TZY
PAR2 PAR2 3x51 174 TM3 Y A thermostabilising 5NDD, 5NDZ, 5NJ6
ACM2 M2 373 ICL3 A T other-effect 4MQT, 4MQS
LPAR1 LPA1 6x59 282 TM6 V C receptor-disulfide-bridge, thermostabilising 4Z36
AA2AR A2A 3x37 89 TM3 Q A thermostabilising 2YDO, 4UG2, 4UHR, 2YDV
CCR9 CCR9 8x63 337 H8 C A palmitoylation-site 5LWE
AA1R A1 7x41 277 TM7 T A thermostabilising 5N2S
NTR1 NTS1 5x36 234 TM5 V L receptor-expression 4BWB, 4BV0, 3ZEV, 4BUO
GLP1R GLP-1 6x45 361 TM6 G C thermostabilising 5VEX, 5VEW
EDNRB ETB 7x48 381 TM7 I A thermostabilising 5XPR, 5X93
Q9WTK1 BLT1 2x67 83 TM2 H G thermostabilising 5X33
OPSD Rhodopsin 2x56 90 TM2 G D natural-mutation-snp-incl-disease-causing 4BEY, 4BEZ
DRD3 D3 3x41 119 TM3 L W thermostabilising 3PBL
APJ apelin 3x40 117 TM3 V A thermostabilising 5VBL
GRM5 mGlu5 675 ICL2 G M thermostabilising 4OO9, 6FFH, 6FFI, 5CGD, 5CGC
OPSD Rhodopsin 6x40 257 TM6 M Y thermostabilising 4A4M
ADRB2 β2 2x66 96 TM2 M T receptor-expression 5JQH, 4GBR, 4QKX, 4LDO, 3SN6, 4LDE, 4LDL
AA2AR A2A 2x62 65 TM2 T A thermostabilising 2YDO, 4UG2, 4UHR, 2YDV
CCR9 CCR9 7x29 294 TM7 N A thermostabilising 5LWE
OPSD Rhodopsin 2 N-term N C receptor-disulfide-bridge, thermostabilising 4BEZ, 2J4Y, 4A4M, 5EN0, 2X72, 3C9M, 5DYS, 4BEY
NTR1 NTS1 2x57 121 TM2 M L receptor-expression 4BWB, 4BV0
APJ apelin 8x59 325 H8 C L palmitoylation-site 5VBL
SMO SMO 3x40 329 TM3 V F receptor-expression, thermostabilising 5L7D, 5L7I
ADRB2 β2 6x27 265 TM6 C A other-effect 5JQH, 4LDO, 4QKX, 4LDE, 4LDL
ADRB2 β2 2x63 93 TM2 H C receptor-ligand-bond, thermostabilising 3PDS, 4QKX
GLP1R GLP-1 7x56 405 TM7 V A thermostabilising 5NX2
GRM5 mGlu5 5x42 742 TM5 T A thermostabilising 4OO9, 6FFH, 6FFI, 5CGD, 5CGC
CRFR1 CRF1 5x48 277 TM5 I A thermostabilising 4Z9G, 4K5Y
NTR1 NTS1 5x54 253 TM5 I A thermostabilising 4BWB, 4BV0, 3ZEV, 4BUO
Q9WTK1 BLT1 3x21 88 TM3 K G thermostabilising 5X33
C5AR1 C5a1 234 ICL3 A E palmitoylation-site 5O9H
ADRB2 β2 3x41 122 TM3 E W receptor-expression, thermostabilising 3D4S, 3NY9, 3NY8, 3NYA
ACM1 M1 12 N-term N Q glycosylation-site 5CXV
NTR1 NTS1 7x41 358 TM7 F A receptor-expression 4GRV, 5T04
CRFR1 CRF1 7x38 349 TM7 S A thermostabilising 4Z9G, 4K5Y
PAR2 PAR2 3x53 176 TM3 V E thermostabilising 5NDD, 5NDZ, 5NJ6
NTR1 NTS1 6x59 332 TM6 C V receptor-expression 4BWB, 4BV0
C5AR1 C5a1 2x59 91 TM2 I A palmitoylation-site 5O9H
CCR9 CCR9 7x39 304 TM7 T A thermostabilising 5LWE
GLP1R GLP-1 6x30 346 TM6 K A thermostabilising 5VEX, 5VEW
GLP1R GLP-1 3x24 225 TM3 S A thermostabilising 5VEX, 5VEW
G1SGD4 GLP-1 106 N-term T A other-effect 5VAI
ACM2 M2 3 N-term N D glycosylation-site 4MQT, 3UON, 4MQS
P2RY1 P2Y1 7x49 320 TM7 D N receptor-expression, thermostabilising 4XNW, 4XNV
GRM5 mGlu5 3x48 667 TM3 N Y thermostabilising 4OO9, 6FFH, 6FFI, 5CGD, 5CGC
GLR glucagon 1x48 154 TM1 G A thermostabilising 5EE7
G1SGD4 GLP-1 1x31 140 TM1 Q R other-effect 5VAI
AA1R A1 2x52 57 TM2 A L thermostabilising 5N2S
P2Y12 P2Y12 7x49 294 TM7 D N receptor-expression, thermostabilising 4NTJ, 4PXZ, 4PY0
CCR9 CCR9 34 N-term T E glycosylation-site 5LWE
PAR2 PAR2 5x64 268 TM5 M A thermostabilising 5NDD, 5NDZ, 5NJ6
PAR2 PAR2 3x34 157 TM3 G A thermostabilising 5NDD, 5NDZ, 5NJ6
CNR1 CB1 5x37 273 TM5 E K receptor-expression, thermostabilising 5TGZ, 5XRA, 5XR8
C5AR1 C5a1 4x45 156 TM4 A L palmitoylation-site 5O9H
C5AR1 C5a1 4x62 172 TM4 F A palmitoylation-site 5O9H
GLP1R GLP-1 5x51 317 TM5 I C thermostabilising 5VEX, 5VEW
AA2AR A2A 7x41 277 TM7 S A thermostabilising 5OLG, 5OLO, 5MZJ, 5OLZ, 5OLV, 5IU7, 3UZA, 5OM4, 5NM2, 5NM4, 3REY, 5OLH, 5NLX, 5IUA, 5IUB, 3UZC, 5IU8, 5MZP, 5IU4, 3PWH, 3RFM, 5OM1, 5N2R
OPSD Rhodopsin 2 N-term N C other-effect, receptor-disulfide-bridge, thermostabilising 5W0P, 4ZWJ, 5DGY
AA1R A1 6x37 236 TM6 L A thermostabilising 5N2S
ADRB2 β2 16 N-term G R other-effect 3NY8, 3P0G, 5D6L, 5D5A, 3NY9, 3NYA, 5X7D, 2RH1, 3D4S, 2R4R, 3KJ6, 5D5B
NTR1 NTS1 2x60 124 TM2 E D receptor-expression 4BWB, 4BV0
GLR glucagon 2x48 182 TM2 A L thermostabilising 5EE7
NTR1 NTS1 213 ECL2 R L receptor-expression 4BWB, 4BV0, 3ZEV, 4BUO
GLP1R GLP-1 207 ECL1 T E thermostabilising 5NX2
NTR1 NTS1 7x43 360 TM7 V A thermostabilising 4XEE, 4GRV, 4XES, 5T04
GRM5 mGlu5 5x53 753 TM5 S A thermostabilising 4OO9, 6FFH, 6FFI, 5CGD, 5CGC
FFAR1 FFA1 5x58 202 TM5 Y F thermostabilising 4PHU, 5TZR, 5TZY
NTR1 NTS1 5x61 260 TM5 I A receptor-expression 4BWB
AA1R A1 159 ECL2 N A glycosylation-site 5N2S, 5UEN
OPSD Rhodopsin 338 C-term S X phosphorylation-site 5W0P
GLR glucagon 2x56 190 TM2 S A thermostabilising 5EE7
OX2R OX2 6x39 308 TM6 I V other-effect 5WS3, 4S0V, 5WQC
NTR1 NTS1 6x37 310 TM6 L A thermostabilising 4GRV
CRFR1 CRF1 6x51 330 TM6 F A thermostabilising 4Z9G, 4K5Y
NTR1 NTS1 7x46 362 TM7 S A receptor-expression 4BWB, 4BV0, 3ZEV, 4BUO
NTR1 NTS1 7x41 358 TM7 F V receptor-expression 4BWB, 4BV0, 3ZEV, 4BUO
NTR1 NTS1 1x51 83 TM1 S G receptor-expression 4BWB, 4BV0
GLP1R GLP-1 2x59 196 TM2 I F thermostabilising 5VEX, 5VEW
GLP1R GLP-1 2x56 193 TM2 S C thermostabilising 5VEX, 5VEW
PAR2 PAR2 6x38 289 TM6 I A thermostabilising 5NDD, 5NDZ, 5NJ6
PAR2 PAR2 3x43 166 TM3 M L thermostabilising 5NDD, 5NDZ, 5NJ6
ACM1 M1 3x37 110 TM3 N Q glycosylation-site 5CXV
GLR glucagon 7x39 387 TM7 F A thermostabilising 5EE7
OPRK κ 3x29 135 TM3 I L receptor-expression 6B73, 4DJH
EDNRB ETB 5x36 270 TM5 K A thermostabilising 5XPR, 5X93
GLP1R GLP-1 5x52 318 TM5 G I thermostabilising 5VEX, 5VEW
EDNRB ETB 405 C-term C A palmitoylation-site 5XPR, 5X93
ADRB1 β1 2x53 90 TM2 M V thermostabilising 2YCW, 2Y01, 2Y04, 2Y00, 2YCY, 2Y02, 5F8U, 3ZPR, 3ZPQ, 2YCX, 4BVN, 5A8E, 2YCZ, 2Y03, 4AMI, 4GPO, 4AMJ, 2VT4
NTR1 NTS1 2x42 105 TM2 H Y receptor-expression 4BWB, 4BV0, 3ZEV, 4BUO
NTR1 NTS1 5x64 263 TM5 K R receptor-expression 4BWB, 4BV0
NTR1 NTS1 6x40 313 TM6 V M receptor-expression 4BV0
GLR glucagon 6x30 344 TM6 K A thermostabilising 5EE7
CNR1 CB1 6x32 340 TM6 R E receptor-expression, thermostabilising 5TGZ, 5XRA, 5XR8
CXCR4 CXCR4 6x36 240 TM6 T P thermostabilising 3OE0, 4RWS, 3OE9
CCR9 CCR9 6x36 255 TM6 V A thermostabilising 5LWE
PAR2 PAR2 6x42 293 TM6 L A thermostabilising 5NDD, 5NDZ, 5NJ6
AA1R A1 8x64 309 H8 C S palmitoylation-site 5N2S
AA2AR A2A 2x50 52 TM2 D N thermostabilising 5WF5
C5AR1 C5a1 34x51 142 ICL2 I A palmitoylation-site 5O9H
GLP1R GLP-1 6x45 361 TM6 G A thermostabilising 5NX2
AA2AR A2A 6x37 235 TM6 L A thermostabilising 5OLG, 5OLO, 5MZJ, 5OLZ, 5OLV, 5IU7, 3UZA, 5OM4, 5NM2, 5NM4, 3REY, 5OLH, 5NLX, 5IUA, 5IUB, 3UZC, 5IU8, 5MZP, 5IU4, 3PWH, 3RFM, 5OM1, 5N2R
CNR1 CB1 3x46 210 TM3 T A thermostabilising 5TGZ, 5XRA, 5U09, 5XR8
GLR glucagon 2x59 193 TM2 V F thermostabilising 5EE7
S1PR1 S1P1 6x31 252 TM6 L V other-effect 3V2Y, 3V2W
FFAR1 FFA1 3x49 103 TM3 G A thermostabilising 4PHU, 5TZR, 5TZY
OPSD Rhodopsin 282 ECL3 D C receptor-disulfide-bridge, thermostabilising 4BEZ, 2J4Y, 4A4M, 5EN0, 2X72, 3C9M, 5DYS, 4BEY
C5AR1 C5a1 311 ICL4 L E palmitoylation-site 5O9H
C5AR1 C5a1 5x68 232 TM5 R A palmitoylation-site 5O9H
GLP1R GLP-1 295 ECL2 G A thermostabilising 5NX2
G1SGD4 GLP-1 112 N-term H P other-effect 5VAI
ADRB1 β1 6x27 282 TM6 A L thermostabilising 2YCW, 2Y01, 2Y04, 2Y00, 2YCY, 2Y02, 5F8U, 3ZPR, 3ZPQ, 2YCX, 4BVN, 5A8E, 2YCZ, 2Y03, 4AMI, 4GPO, 4AMJ, 2VT4
GLR glucagon 207 ECL1 G E thermostabilising 5EE7
CCR9 CCR9 3x47 141 TM3 S C thermostabilising 5LWE
ADRB1 β1 1x59 68 TM1 R S thermostabilising 2YCW, 2Y01, 2Y04, 2Y00, 2YCY, 2Y02, 5F8U, 3ZPR, 3ZPQ, 2YCX, 4BVN, 5A8E, 2YCZ, 2Y03, 4AMI, 4GPO, 4AMJ, 2VT4
NTR1 NTS1 3x55 172 TM3 C R receptor-expression 4BV0
ADRB1 β1 7x48 338 TM7 F M thermostabilising 2YCW, 2Y01, 2Y04, 2Y00, 2YCY, 2Y02, 5F8U, 3ZPR, 3ZPQ, 2YCX, 4BVN, 5A8E, 2YCZ, 2Y03, 4AMI, 4GPO, 4AMJ, 2VT4
NTR1 NTS1 3x33 150 TM3 D E receptor-expression 4BWB, 4BV0
NTR1 NTS1 5x63 262 TM5 N R receptor-expression 4BWB, 4BV0
ACM2 M2 9 N-term N D glycosylation-site 4MQT, 3UON, 4MQS
NTR1 NTS1 7x25 342 TM7 F A receptor-expression 4BWB, 4BV0
CCR9 CCR9 5x41 216 TM5 T A thermostabilising 5LWE
PAR2 PAR2 222 ECL2 N Q glycosylation-site 5NDD, 5NDZ, 5NJ6
GLP1R GLP-1 215 ECL1 D R thermostabilising 5NX2
OPSD Rhodopsin 18 N-term V I other-effect 2ZIY
C5AR1 C5a1 8x54 321 H8 N E palmitoylation-site 5O9H
APJ apelin 8x60 326 H8 C M palmitoylation-site 5VBL
OPSD Rhodopsin 3x28 113 TM3 E Q thermostabilising 5W0P, 4ZWJ, 5DGY
GLR glucagon 4x54 276 TM4 M A thermostabilising 5EE7
NTR1 NTS1 3x26 143 TM3 R K receptor-expression 4BWB, 4BV0
CNR1 CB1 5x47 283 TM5 T V receptor-expression 5TGZ, 5XRA, 5XR8
OPSD Rhodopsin 3x28 113 TM3 E Q thermostabilising 2X72
NTR1 NTS1 2x551 119 TM2 L F receptor-expression 4BWB, 4BV0
OPSD Rhodopsin 336 C-term T X phosphorylation-site 5W0P
ACM2 M2 374 ICL3 K R other-effect 4MQT, 4MQS
CRFR1 CRF1 1x60 144 TM1 L A thermostabilising 4Z9G, 4K5Y
CCR9 CCR9 12x48 77 ICL1 T A thermostabilising 5LWE
GLR glucagon 2x39 173 TM2 R A thermostabilising 5EE7, 5YQZ
GLP1R GLP-1 4x48 271 TM4 S A thermostabilising 5VEX, 5VEW
PAR1 PAR1 250 ECL2 N G glycosylation-site 3VW7
CRFR1 CRF1 6x30 309 TM6 Y A thermostabilising 4Z9G, 4K5Y
OPSD Rhodopsin 2x60 94 TM2 T I thermostabilising 5DYS, 5EN0
EDNRB ETB 6x54 342 TM6 S A thermostabilising 5XPR, 5X93
DRD2 D2 6x37 375 TM6 L A thermostabilising 6CM4
ADRB1 β1 3x40 129 TM3 I V thermostabilising 4BVN, 5A8E
S1PR1 S1P1 6x30 251 TM6 S N other-effect 3V2Y, 3V2W
APJ apelin 177 ECL2 T N glycosylation-site 5VBL
CCR9 CCR9 2x38 82 TM2 M A thermostabilising 5LWE
DRD2 D2 6x41 379 TM6 L A thermostabilising 6CM4
CRFR1 CRF1 2x48 160 TM2 S A thermostabilising 4Z9G, 4K5Y
CCR5 CCR5 8x49 303 H8 K E thermostabilising 5UIW, 4MBS
NTR1 NTS1 2x38 101 TM2 T R receptor-expression 4BWB, 4BV0
AA2AR A2A 2x46 48 TM2 L A thermostabilising 2YDO, 4UG2, 4UHR, 2YDV
Q9WTK1 BLT1 5x67 212 TM5 V A thermostabilising 5X33
AA2AR A2A 3x39 91 TM3 S A thermostabilising 5WF6
AA2AR A2A 3x36 88 TM3 T A thermostabilising 5OLG, 5OLO, 5MZJ, 5OLZ, 5OLV, 5IU7, 3UZA, 5OM4, 5NM2, 5NM4, 3REY, 5OLH, 5NLX, 5IUA, 5IUB, 3UZC, 5IU8, 5MZP, 5IU4, 3PWH, 3RFM, 5OM1, 5N2R
GLP1R GLP-1 6x42 358 TM6 P A thermostabilising 5NX2
NTR1 NTS1 6x32 305 TM6 H R receptor-expression 4BWB, 4BV0, 3ZEV, 4BUO
AA2AR A2A 3x55 107 TM3 R A thermostabilising 5OLG, 5OLO, 5MZJ, 5OLZ, 5OLV, 5IU7, 3UZA, 5OM4, 5NM2, 5NM4, 3REY, 5OLH, 5NLX, 5IUA, 5IUB, 3UZC, 5IU8, 5MZP, 5IU4, 3PWH, 3RFM, 5OM1, 5N2R
ACM2 M2 2 N-term N D glycosylation-site 4MQT, 3UON, 4MQS
AA2AR A2A 154 ECL2 N A glycosylation-site 5OLG, 5OLO, 5MZJ, 5OLZ, 5OLV, 5IU7, 5OM4, 5G53, 5NM2, 5NM4, 4UG2, 5OLH, 2YDO, 5NLX, 5IUA, 5IUB, 4UHR, 5IU8, 2YDV, 5MZP, 5IU4, 5OM1, 5N2R
AA2AR A2A 2x52 54 TM2 A L thermostabilising 5OLG, 5OLO, 5MZJ, 5OLZ, 5OLV, 5IU7, 3UZA, 5OM4, 5NM2, 5NM4, 4UG2, 3REY, 5OLH, 2YDO, 5NLX, 5IUA, 5IUB, 3UZC, 4UHR, 5IU8, 2YDV, 5MZP, 5IU4, 3PWH, 3RFM, 5OM1, 5N2R
DRD2 D2 3x40 122 TM3 I A thermostabilising 6CM4
CXCR4 CXCR4 3x41 125 TM3 L W thermostabilising 3OE8, 4RWS, 3OE9, 3ODU, 3OE0, 3OE6
GLP1R GLP-1 211 ECL1 Q A thermostabilising 5NX2
EDNRB ETB 1x55 124 TM1 R Y thermostabilising 5XPR, 5X93
GLR glucagon 3x24 223 TM3 G A thermostabilising 5EE7
5HT1B 5-HT1B 3x41 138 TM3 L W thermostabilising 4IAQ, 4IAR, 5V54
OPSD Rhodopsin 6x40 257 TM6 M Y thermostabilising 5W0P, 4ZWJ, 5DGY
CRFR1 CRF1 4x43 228 TM4 K A thermostabilising 4Z9G, 4K5Y
NTR1 NTS1 7x37 354 TM7 T S receptor-expression 4BWB, 4BV0
AA1R A1 6x41 240 TM6 L A thermostabilising 5N2S
NTR1 NTS1 215 ECL2 G A thermostabilising 4XEE, 4GRV, 4XES, 5T04
LPAR1 LPA1 5x37 204 TM5 D C receptor-disulfide-bridge, thermostabilising 4Z36
ADRB1 β1 7x53 343 TM7 Y L thermostabilising 4BVN, 5A8E
NTR1 NTS1 5x42 240 TM5 V L receptor-expression 4BWB, 4BV0
NTR1 NTS1 2x40 103 TM2 H D receptor-expression 4BWB, 4BV0, 3ZEV, 4BUO
ACM1 M1 2 N-term N Q glycosylation-site 5CXV
CCR5 CCR5 6x33 233 TM6 A D receptor-salt-bridge, thermostabilising 5UIW, 4MBS
AA2AR A2A 5x63 202 TM5 L A thermostabilising 5OLG, 5OLO, 5MZJ, 5OLZ, 5OLV, 5IU7, 3UZA, 5OM4, 5NM2, 5NM4, 3REY, 5OLH, 5NLX, 5IUA, 5IUB, 3UZC, 5IU8, 5MZP, 5IU4, 3PWH, 3RFM, 5OM1, 5N2R
EDNRB ETB 8x57 400 H8 C A palmitoylation-site 5XPR, 5X93
NTR1 NTS1 2x61 125 TM2 L V receptor-expression 4BV0
GLP1R GLP-1 6x31 347 TM6 C F thermostabilising 5VEX, 5VEW
CCR9 CCR9 12x50 79 ICL1 V A thermostabilising 5LWE
GLP1R GLP-1 45x52 298 ECL2 T A thermostabilising 5NX2
PAR2 PAR2 1x46 89 TM1 G A thermostabilising 5NDD, 5NDZ, 5NJ6
APJ apelin 6x48 261 TM6 W K thermostabilising 5VBL
GLP1R GLP-1 260 ICL2 L F other-effect, thermostabilising 5NX2
GLP1R GLP-1 6x47 363 TM6 H V thermostabilising 5NX2
GLP1R GLP-1 3x32 233 TM3 M C thermostabilising 5VEX, 5VEW
ACM2 M2 6 N-term N D glycosylation-site 4MQT, 3UON, 4MQS
CRFR1 CRF1 45x52 260 ECL2 F A thermostabilising 4Z9G, 4K5Y
PAR1 PAR1 259 ECL2 N S glycosylation-site 3VW7
NTR1 NTS1 3x50 167 TM3 R L receptor-expression 4BWB, 4BV0, 3ZEV, 4BUO
CXCR4 CXCR4 45x51 187 ECL2 D C receptor-ligand-bond, thermostabilising 4RWS
AA1R A1 3x36 91 TM3 T A thermostabilising 5N2S
OPSD Rhodopsin 282 ECL3 N C receptor-disulfide-bridge, thermostabilising 5W0P, 4ZWJ, 5DGY
ADRB2 β2 187 ECL2 N E glycosylation-site 5D5B, 3NY8, 3P0G, 5JQH, 5D6L, 3PDS, 5D5A, 3NY9, 3NYA, 5X7D, 4GBR, 4QKX, 2RH1, 3D4S, 4LDO, 3KJ6, 3SN6, 4LDE, 4LDL
C5AR1 C5a1 8x50 317 H8 S E palmitoylation-site 5O9H
GLR glucagon 6x48 362 TM6 E F thermostabilising 5EE7