Drug Browser

Drug Name Indication Target Target Level Class Family Status Phase Clinical Status Year of Approval Drug Type Mechanism of Action References NHS
abaloparatide Anti-osteoporotic pth1r_human primary Class B1 (Secretin) Parathyroid hormone receptors approved 4 - 2017 peptide agonist 28389324 | 26562265 no
abarelix Antineoplastic gnrhr_human primary Class A (Rhodopsin) Gonadotrophin-releasing hormone receptors approved 4 - 2003 peptide antagonist 16985933 no
acamprosate Antineoplastic grm5_human secondary Class C (Glutamate) Metabotropic glutamate receptors approved 4 - 2004 small molecule antagonist 15963001 yes
acebutolol Antihypertensive adrb1_human primary Class A (Rhodopsin) Adrenoceptors approved 4 - 1984 small molecule antagonist 2453744 | 2568935 | 16268148 | 11752352 yes
acepromazine, aceprometazine Antipsychotic drd1_human primary Class A (Rhodopsin) Dopamine receptors approved 4 - - small molecule antagonist 7918347 no
acepromazine, aceprometazine Antipsychotic 5ht2a_human primary Class A (Rhodopsin) 5-Hydroxytryptamine receptors approved 4 - - small molecule antagonist 10821438 | 8593484 no
acepromazine, aceprometazine Antipsychotic drd2_human primary Class A (Rhodopsin) Dopamine receptors approved 4 - - small molecule antagonist 11103886 | 11873706 | 15694263 | 16867246 | 11752352 | 20643630 no
acepromazine, aceprometazine Antipsychotic 5ht1a_human primary Class A (Rhodopsin) 5-Hydroxytryptamine receptors approved 4 - - small molecule antagonist 11755134 | 9760039 no
acepromazine, aceprometazine Hypnotics and Sedatives hrh1_human primary Class A (Rhodopsin) Histamine receptors approved 4 - - small molecule antagonist 17139284 | 17016423 | 4406367 | 11752352 no
acetophenazine schizophrenia drd1_human primary Class A (Rhodopsin) Dopamine receptors approved 4 - 1961 small molecule antagonist 17139284 | 17016423 no
acetophenazine schizophrenia drd2_human primary Class A (Rhodopsin) Dopamine receptors approved 4 - 1961 small molecule antagonist 17139284 | 17016423 | 11873706 | 6147851 | 11752352 no
acetylcholine Antiglaucomic acm3_human primary Class A (Rhodopsin) Acetylcholine receptors (muscarinic) approved 4 - 1973 small molecule agonist 508313 yes
acipimox lipid-lowering hcar2_human primary Class A (Rhodopsin) Hydroxycarboxylic acid receptors approved 4 - 2003 small molecule agonist 22267479 yes
agomelatine Anti-depressant 5ht2c_human primary Class A (Rhodopsin) 5-Hydroxytryptamine receptors approved 4 - 2009 small molecule antagonist 15289999 yes
agomelatine Anti-depressant mtr1a_human primary Class A (Rhodopsin) Melatonin approved 4 - 2009 small molecule agonist 15289999 yes
agomelatine Anti-depressant mtr1b_human primary Class A (Rhodopsin) Melatonin approved 4 - 2009 small molecule agonist 15289999 yes
aclidinium Bronchodilator acm1_human primary Class A (Rhodopsin) Acetylcholine receptors (muscarinic) approved 4 - 2012 small molecule antagonist 19710368 | 19478135 yes
aclidinium Bronchodilator acm2_human primary Class A (Rhodopsin) Acetylcholine receptors (muscarinic) approved 4 - 2012 small molecule antagonist 19710368 | 19478135 yes
aclidinium Bronchodilator acm3_human primary Class A (Rhodopsin) Acetylcholine receptors (muscarinic) approved 4 - 2012 small molecule antagonist 19710368 | 19478135 yes
aclidinium Bronchodilator acm4_human primary Class A (Rhodopsin) Acetylcholine receptors (muscarinic) approved 4 - 2012 small molecule antagonist 19710368 | 19478135 yes
aclidinium Bronchodilator acm5_human primary Class A (Rhodopsin) Acetylcholine receptors (muscarinic) approved 4 - 2012 small molecule antagonist 19710368 | 19478135 yes
acrivastine Anti-Allergic hrh1_human primary Class A (Rhodopsin) Histamine receptors approved 4 - 1994 small molecule antagonist 1715267 yes
adenosine Analgesics aa3r_human primary Class A (Rhodopsin) Adenosine receptors approved 4 - 1989 small molecule agonist 11752352 | 20370662 | 20370661 | 17321471 | 16339914 | 20136829 | 17438146 | 17442976 yes
adenosine Analgesics aa2ar_human primary Class A (Rhodopsin) Adenosine receptors approved 4 - 1989 small molecule agonist 20370662 | 20370661 | 17321471 | 16339914 | 19749080 | 20136829 | 17438146 | 17442976 yes
adenosine Analgesics aa2br_human primary Class A (Rhodopsin) Adenosine receptors approved 4 - 1989 small molecule agonist 20370662 | 20370661 | 17321471 | 16339914 | 20136829 | 17438146 | 17442976 yes
adenosine Analgesics aa1r_human primary Class A (Rhodopsin) Adenosine receptors approved 4 - 1989 small molecule agonist 20370662 | 20370661 | 17321471 | 20136829 | 17438146 | 17442976 yes
albiglutide Antidiabetic glp1r_human primary Class B1 (Secretin) Glucagon receptor family approved 4 - 2014 protein agonist 25136065 yes
albuterol chronic obstructive pulmonary disease (COPD) adrb2_human primary Class A (Rhodopsin) Adrenoceptors approved 4 - 1981 small molecule agonist 17996583 no
alcaftadine Anti-Allergic hrh1_human primary Class A (Rhodopsin) Histamine receptors approved 4 - 2010 small molecule antagonist 22035879 no
almotriptan Anti-migraine 5ht1d_human primary Class A (Rhodopsin) 5-Hydroxytryptamine receptors approved 4 - 2001 small molecule agonist 10193663 | 11134654 | 11642004 | 11752352 yes
alfentanil Analgesics oprm_human primary Class A (Rhodopsin) Opioid receptors approved 4 - 1986 small molecule agonist 10955836 | 15694871 | 16906017 | 11240090 | 11752352 yes
alfuzosin benign prostatic hyperplasia ada1a_human primary Class A (Rhodopsin) Adrenoceptors approved 4 - 2003 small molecule agonist 11752352 | 8799556 | 12892027 | 9122046 | 15639685 | 9223558 | 8196478 | 9870119 | 16613526 | 16553574 | 11750253 yes
alfuzosin benign prostatic hyperplasia ada1d_human primary Class A (Rhodopsin) Adrenoceptors approved 4 - 2003 small molecule agonist 11752352 | 8799556 | 9122046 | 15639685 | 8196478 | 16613526 | 16553574 | 11750253 yes
alfuzosin benign prostatic hyperplasia ada1b_human primary Class A (Rhodopsin) Adrenoceptors approved 4 - 2003 small molecule agonist 11752352 | 8799556 | 9122046 | 15639685 | 8196478 | 9870119 | 16613526 | 16553574 | 11750253 yes
almotriptan Anti-migraine 5ht1b_human primary Class A (Rhodopsin) 5-Hydroxytryptamine receptors approved 4 - 2001 small molecule agonist 10193663 | 10824628 | 11050304 | 11069595 | 11134654 | 11752352 yes
alprenolol Anti-Arrhythmia ; Antihypertensive adrb2_human primary Class A (Rhodopsin) Adrenoceptors approved 4 - 1966 small molecule antagonist 2439825 | 2859531 | 2871880 no
alprenolol Anti-Arrhythmia ; Antihypertensive adrb1_human primary Class A (Rhodopsin) Adrenoceptors approved 4 - 1966 small molecule antagonist 7678677 | 7606348 | 10433496 | 12522078 | 2828119 | 11752352 no
alprostadil sexual dysfunction pe2r2_human primary Class A (Rhodopsin) Prostanoid receptors approved 4 - 1981 small molecule agonist 10509658 | 15840408 | 11752352 yes
alprostadil sexual dysfunction pe2r1_human primary Class A (Rhodopsin) Prostanoid receptors approved 4 - 1981 small molecule agonist 15560119 | 14561849 | 10670413 | 16516814 | 11524243 yes
alverine Antispasmodics 5ht1a_human primary Class A (Rhodopsin) 5-Hydroxytryptamine receptors approved 4 - 2014 small molecule antagonist 11697552 yes
alvimopan opioid-induced bowel dysfunction oprm_human primary Class A (Rhodopsin) Opioid receptors approved 4 - 2008 small molecule antagonist 17909271 | 19086236 | 16597533 | 11752352 | 15882122 | 11755894 no
alvimopan Opiate Antagonists oprm_human primary Class A (Rhodopsin) Opioid receptors approved 4 - 2008 small molecule antagonist 17909271 | 19086236 | 16597533 | 11752352 | 15882122 | 11755894 no
amantadine hcl dyskinesias drd2_human primary Class A (Rhodopsin) Dopamine receptors approved 4 - 1968 small molecule antagonist 9195603 | 10443547 no
ambrisentan Antihypertensive ednra_human primary Class A (Rhodopsin) Endothelin receptors approved 4 - 2007 small molecule antagonist 20811346 | 19389876 | 19601701 | 19920913 yes
amiodarone Anti-Arrhythmia adrb1_human primary Class A (Rhodopsin) Adrenoceptors approved 4 - 1985 small molecule antagonist 12083991 yes
amitriptyline Analgesics 5ht2a_human primary Class A (Rhodopsin) 5-Hydroxytryptamine receptors approved 4 - 1961 small molecule antagonist 7855217 yes
amoxapine unipolar depression drd1_human primary Class A (Rhodopsin) Dopamine receptors approved 4 - 1980 small molecule antagonist 11180191 yes
amoxapine unipolar depression drd3_human primary Class A (Rhodopsin) Dopamine receptors approved 4 - 1980 small molecule antagonist 16135699 yes
amoxapine unipolar depression drd4_human primary Class A (Rhodopsin) Dopamine receptors approved 4 - 1980 small molecule antagonist 16135699 yes
amoxapine unipolar depression drd2_human primary Class A (Rhodopsin) Dopamine receptors approved 4 - 1980 small molecule antagonist 1966571 | 11180191 yes
amphetamine cognitive dysfunction; ADHD taar1_human secondary Class A (Rhodopsin) Trace amine receptors approved 4 - 1996 small molecule agonist 17218486 | 17234900 | 17212650 | 17234899 | 15764732 no
anileridine Analgesics; Narcotics oprm_human primary Class A (Rhodopsin) Opioid receptors approved 4 - 1982 small molecule agonist 17139284 | 17016423 | 11752352 no
anisotropine methylbromide Antispasmodics; Anti-ulcer acm2_human primary Class A (Rhodopsin) Acetylcholine receptors (muscarinic) approved 4 - 1982 small molecule antagonist 17139284 | 17016423 | 4555460 no
anisotropine methylbromide Antispasmodics; Anti-ulcer acm3_human primary Class A (Rhodopsin) Acetylcholine receptors (muscarinic) approved 4 - 1982 small molecule antagonist 17139284 | 17016423 | 4555460 no
anisotropine methylbromide Antispasmodics; Anti-ulcer acm1_human primary Class A (Rhodopsin) Acetylcholine receptors (muscarinic) approved 4 - 1982 small molecule antagonist 17139284 | 17016423 | 4555460 | 6897316 | 20391952 no
antazoline atrial fibrillation hrh1_human primary Class A (Rhodopsin) Histamine receptors approved 4 - 1994 small molecule antagonist 16129921 yes
apomorphine anti-parkisonian drd3_human primary Class A (Rhodopsin) Dopamine receptors approved 4 - 2004 small molecule agonist 11752352 yes
apomorphine anti-parkisonian drd2_human primary Class A (Rhodopsin) Dopamine receptors approved 4 - 2004 small molecule agonist 11343576 | 11752352 | 11212866 | 18691132 | 10641988 | 11692072 | 11215397 | 10494453 yes
apomorphine anti-parkisonian drd4_human primary Class A (Rhodopsin) Dopamine receptors approved 4 - 2004 small molecule agonist 15007532 | 11752352 | 18691132 | 9497025 | 17067298 | 9871530 | 17164075 yes
asenapine schizophrenia 5ht1a_human primary Class A (Rhodopsin) 5-Hydroxytryptamine receptors approved 4 - 2009 small molecule antagonist 10592235 | 18308814 yes
apraclonidine Antiglaucomic ada2b_human primary Class A (Rhodopsin) Adrenoceptors approved 4 - 1987 small molecule agonist 1676991 yes
apraclonidine Antiglaucomic ada2c_human primary Class A (Rhodopsin) Adrenoceptors approved 4 - 1987 small molecule agonist 1676991 yes
apraclonidine Antiglaucomic ada2a_human primary Class A (Rhodopsin) Adrenoceptors approved 4 - 1987 small molecule agonist 17139284 | 17016423 | 11481271 | 17824139 | 16921219 | 12630335 | 14575724 | 15748550 | 20399934 | 17572343 | 16935593 yes
aprepitant Antiemetics nk1r_human primary Class A (Rhodopsin) Tachykinin receptors approved 4 - 2003 small molecule antagonist 11752352 | 12590540 | 17643344 | 12784346 | 12227806 | 15121485 yes
arbutamine Cardiotonic adrb1_human primary Class A (Rhodopsin) Adrenoceptors approved 4 - 1997 small molecule agonist 17139284 | 17016423 | 8723169 no
arformoterol Bronchodilator adrb2_human primary Class A (Rhodopsin) Adrenoceptors approved 4 - 2006 small molecule agonist 14725487 | 17594727 | 17352511 | 20406080 | 16022567 | 18501650 | 17472819 | 11752352 no
aripiprazole schizophrenia 5ht1a_human primary Class A (Rhodopsin) 5-Hydroxytryptamine receptors approved 4 - 2002 small molecule partial agonist 12063084 | 14647959 | 14709325 | 15257633 | 15862515 yes
aripiprazole psychosis 5ht1a_human primary Class A (Rhodopsin) 5-Hydroxytryptamine receptors approved 4 - 2015 small molecule partial agonist 12063084 | 14647959 | 14709325 | 15257633 | 15862515 yes
aripiprazole schizophrenia 5ht2a_human primary Class A (Rhodopsin) 5-Hydroxytryptamine receptors approved 4 - 2002 small molecule partial agonist 14642974 | 17242925 | 17265076 yes
aripiprazole psychosis 5ht2a_human primary Class A (Rhodopsin) 5-Hydroxytryptamine receptors approved 4 - 2015 small molecule partial agonist 14642974 | 17242925 | 17265076 yes
aripiprazole schizophrenia drd2_human primary Class A (Rhodopsin) Dopamine receptors approved 4 - 2002 small molecule partial agonist 16366516 | 9083792 | 16925992 | 16981227 | 17501690 | 11752352 yes
aripiprazole psychosis drd2_human primary Class A (Rhodopsin) Dopamine receptors approved 4 - 2015 small molecule partial agonist 16366516 | 9083792 | 16925992 | 16981227 | 17501690 | 11752352 yes
asenapine schizophrenia 5ht2a_human primary Class A (Rhodopsin) 5-Hydroxytryptamine receptors approved 4 - 2009 small molecule antagonist 10592235 | 21655346 | 18308814 yes
asenapine schizophrenia 5ht2c_human primary Class A (Rhodopsin) 5-Hydroxytryptamine receptors approved 4 - 2009 small molecule antagonist 10592235 | 21655346 | 18308814 yes
asenapine schizophrenia 5ht6r_human primary Class A (Rhodopsin) 5-Hydroxytryptamine receptors approved 4 - 2009 small molecule antagonist 10592235 | 21655346 | 18308814 yes
atropine nerve antidote acm1_human primary Class A (Rhodopsin) Acetylcholine receptors (muscarinic) approved 4 - 1973 small molecule antagonist 7855217 | 17139284 | 17016423 yes
atropine nerve antidote acm3_human primary Class A (Rhodopsin) Acetylcholine receptors (muscarinic) approved 4 - 1973 small molecule antagonist 7855217 | 17139284 | 17016423 yes
atropine nerve antidote acm4_human primary Class A (Rhodopsin) Acetylcholine receptors (muscarinic) approved 4 - 1973 small molecule antagonist 7855217 | 17139284 | 17016423 yes
asenapine schizophrenia 5ht1b_human primary Class A (Rhodopsin) 5-Hydroxytryptamine receptors approved 4 - 2009 small molecule antagonist 21655346 | 18308814 yes
asenapine schizophrenia 5ht5a_human primary Class A (Rhodopsin) 5-Hydroxytryptamine receptors approved 4 - 2009 small molecule antagonist 21655346 | 18308814 yes
asenapine schizophrenia 5ht7r_human primary Class A (Rhodopsin) 5-Hydroxytryptamine receptors approved 4 - 2009 small molecule antagonist 21655346 | 18308814 yes
asenapine schizophrenia drd2_human primary Class A (Rhodopsin) Dopamine receptors approved 4 - 2009 small molecule antagonist 21655346 | 21658377 | 18308814 yes
asfotase alfa hypophosphatasia s1pr1_human primary Class A (Rhodopsin) Lysophospholipid (S1P) receptors approved 4 - 2015 enzyme agonist 20446681 | 21345969 no
astemizole Anti-Allergic hrh1_human primary Class A (Rhodopsin) Histamine receptors approved 4 - 1988 small molecule antagonist 8001268 | 6146346 | 3147222 | 10597865 | 10597866 | 6204835 | 2892659 | 11752352 no
atenolol Anti-Arrhythmia ; Antihypertensive adrb1_human primary Class A (Rhodopsin) Adrenoceptors approved 4 - 1981 small molecule antagonist 10913016 | 12065078 | 17628611 | 9300315 | 11752352 yes
atosiban labor repressant oxyr_human primary Class A (Rhodopsin) Vasopressin and oxytocin receptors approved 4 - 2013 small molecule antagonist 22069312 no
atropine nerve antidote acm2_human primary Class A (Rhodopsin) Acetylcholine receptors (muscarinic) approved 4 - 1973 small molecule antagonist 16248990 | 17087737 | 15333678 | 17588565 | 16188951 | 7855217 yes
atropine nerve antidote acm5_human primary Class A (Rhodopsin) Acetylcholine receptors (muscarinic) approved 4 - 1973 small molecule antagonist 7855217 | 17139284 | 17016423 | 11752352 yes
azatadine Anti-Allergic hrh1_human primary Class A (Rhodopsin) Histamine receptors approved 4 - 1977 small molecule antagonist 9638277 | 2568212 | 2523301 | 7528133 | 11752352 yes
azilsartan medoxomil Antihypertensive agtr1_human primary Class A (Rhodopsin) Angiotensin receptors approved 4 - 2011 small molecule antagonist 11752352 | 23563275 yes
azelastine Anti-Allergic hrh1_human primary Class A (Rhodopsin) Histamine receptors approved 4 - 1996 small molecule antagonist 2540229 | 8829888 | 9585822 | 11752352 | 19209282 | 17723160 | 10478514 yes
azelastine Anti-Allergic hrh1_human primary Class A (Rhodopsin) Histamine receptors approved 4 - 2012 small molecule antagonist 2540229 | 8829888 | 9585822 | 11752352 | 19209282 | 17723160 | 10478514 yes
baclofen anti-spastic gabr2_human primary Class C (Glutamate) GABAB receptors approved 4 - 1977 small molecule agonist 10658574 | 15235087 | 8388192 | 10751439 | 11008066 | 19303900 | 10328880 | 10545129 yes
baclofen anti-spastic gabr1_human primary Class C (Glutamate) GABAB receptors approved 4 - 1977 small molecule agonist 8388192 | 11752352 | 10386831 | 19303900 | 10444662 | 10482760 | 10494996 | 10545129 | 10094428 yes
benperidol Antipsychotic drd2_human primary Class A (Rhodopsin) Dopamine receptors approved 4 - 2006 small molecule antagonist 27241797 yes
benzphetamine Central Nervous System Stimulants ada1a_human primary Class A (Rhodopsin) Adrenoceptors approved 4 - 1960 small molecule agonist 17139284 | 17016423 no
benzphetamine Central Nervous System Stimulants ada2a_human primary Class A (Rhodopsin) Adrenoceptors approved 4 - 1960 small molecule agonist 17139284 | 17016423 no
benztropine Antiparkinson acm1_human primary Class A (Rhodopsin) Acetylcholine receptors (muscarinic) approved 4 - 1954 small molecule antagonist 16460947 no
bepotastine Anti-Allergic hrh1_human primary Class A (Rhodopsin) Histamine receptors approved 4 - 2009 small molecule antagonist 16914135 | 11752352 no
betahistine vertigo hrh1_human primary Class A (Rhodopsin) Histamine receptors approved 4 - 1970 small molecule agonist 18447604 | 11700150 yes
betahistine vertigo hrh3_human primary Class A (Rhodopsin) Histamine receptors approved 4 - 1970 small molecule antagonist 18447604 | 11700150 | 20530654 yes
betanechol Antidiabetic acm2_human primary Class A (Rhodopsin) Acetylcholine receptors (muscarinic) approved 4 - 1970 small molecule agonist 11798291 | 17413603 no
betaxolol Antihypertensive adrb1_human primary Class A (Rhodopsin) Adrenoceptors approved 4 - 1985 small molecule antagonist 12181453 | 17513029 | 2077180 | 2891463 | 11752352 yes
betazole Diagnostic hrh2_human primary Class A (Rhodopsin) Histamine receptors approved 4 - 1982 small molecule agonist 2892392 | 3661710 | 2886642 | 2874214 | 7213132 | 11752352 no
bethanechol eosinophilic esophagitis acm2_human primary Class A (Rhodopsin) Acetylcholine receptors (muscarinic) approved 4 - 1948 small molecule agonist 17139284 | 17016423 | 17413603 | 11798291 | 16953191 yes
brimonidine Antiglaucomic ada2b_human primary Class A (Rhodopsin) Adrenoceptors approved 4 - 1996 small molecule agonist 14610637 | 8097565 yes
bethanidine Antihypertensive ada1a_human primary Class A (Rhodopsin) Adrenoceptors approved 4 - 1982 small molecule agonist 11752352 no
bethanidine Antihypertensive ada1b_human primary Class A (Rhodopsin) Adrenoceptors approved 4 - 1982 small molecule agonist 11752352 no
bethanidine Antihypertensive ada1d_human primary Class A (Rhodopsin) Adrenoceptors approved 4 - 1982 small molecule agonist 11752352 no
bromocriptine Antidiabetic drd2_human primary Class A (Rhodopsin) Dopamine receptors approved 4 - 1978 small molecule agonist 12010185 | 11752352 | 18691132 | 10641988 | 10626749 | 12753422 | 10721819 | 11444429 yes
bethanidine Antihypertensive ada2a_human primary Class A (Rhodopsin) Adrenoceptors approved 4 - 1982 small molecule agonist 11752352 | 2545383 no
bethanidine Antihypertensive ada2b_human primary Class A (Rhodopsin) Adrenoceptors approved 4 - 1982 small molecule agonist 11752352 | 2545383 no
bethanidine Antihypertensive ada2c_human primary Class A (Rhodopsin) Adrenoceptors approved 4 - 1982 small molecule agonist 11752352 | 2545383 no
bilastine Anti-Allergic hrh1_human primary Class A (Rhodopsin) Histamine receptors approved 4 - 2010 small molecule antagonist 27110120 yes
bimatoprost Antiglaucomic pf2r_human primary Class A (Rhodopsin) Prostanoid receptors approved 4 - 2001 small molecule agonist 11740958 | 12222762 | 14733708 | 18452763 | 689791 | 19697832 | 17724194 | 11752352 yes
bimatoprost Antiglaucomic pe2r1_human primary Class A (Rhodopsin) Prostanoid receptors approved 4 - 2001 small molecule agonist 14733708 | 16877408 yes
bimatoprost Antiglaucomic pe2r3_human primary Class A (Rhodopsin) Prostanoid receptors approved 4 - 2001 small molecule agonist 14733708 | 19232013 | 16877408 yes
biperiden Antidyskinetics acm1_human primary Class A (Rhodopsin) Acetylcholine receptors (muscarinic) approved 4 - 1959 small molecule antagonist 17139284 | 17016423 | 10907719 | 9798802 | 10370904 | 8081071 | 11752352 yes
bisoprolol Antihypertensive adrb1_human primary Class A (Rhodopsin) Adrenoceptors approved 4 - 1992 small molecule antagonist 1280737 | 14757145 | 16325050 | 1676675 | 1691366 | 11752352 yes
bitolterol obstructive lung disease adrb2_human primary Class A (Rhodopsin) Adrenoceptors approved 4 - 1984 small molecule agonist 17139284 | 17016423 | 10796631 | 3278878 no
bopindolol Antihypertensive adrb1_human primary Class A (Rhodopsin) Adrenoceptors approved 4 - - small molecule partial agonist 11752352 | 14608456 | 1687398 | 2148726 | 8884690 | 2907348 no
bosentan Antihypertensive ednra_human primary Class A (Rhodopsin) Endothelin receptors approved 4 - 2001 small molecule antagonist 11728166 | 11752352 | 11447307 | 11704565 | 10961375 | 11849873 yes
bosentan Antihypertensive ednrb_human primary Class A (Rhodopsin) Endothelin receptors approved 4 - 2001 small molecule antagonist 11752352 | 7921608 | 16335785 | 9806221 | 7858879 | 15629255 yes
bromocriptine Antidiabetic drd3_human primary Class A (Rhodopsin) Dopamine receptors approved 4 - 1978 small molecule agonist 18691132 | 10641988 yes
brexpiprazole Anti-depressant 5ht1a_human primary Class A (Rhodopsin) 5-Hydroxytryptamine receptors approved 4 - 2015 small molecule partial agonist 24947465 no
brexpiprazole Anti-depressant 5ht2a_human primary Class A (Rhodopsin) 5-Hydroxytryptamine receptors approved 4 - 2015 small molecule partial agonist 24947465 no
brexpiprazole Anti-depressant drd2_human primary Class A (Rhodopsin) Dopamine receptors approved 4 - 2015 small molecule partial agonist 24947465 no
bromodiphenhydramine Anti-Allergic hrh1_human primary Class A (Rhodopsin) Histamine receptors approved 4 - 1954 small molecule antagonist 17139284 | 17016423 | 11752352 no
brimonidine Antiglaucomic ada2a_human primary Class A (Rhodopsin) Adrenoceptors approved 4 - 1996 small molecule agonist 10799649 | 11481271 | 1373179 | 11752352 yes
brimonidine Antiglaucomic ada2c_human primary Class A (Rhodopsin) Adrenoceptors approved 4 - 1996 small molecule agonist 14610637 | 11606316 | 12670699 | 16757535 yes
bromopride Antiemetics drd2_human primary Class A (Rhodopsin) Dopamine receptors approved 4 - - small molecule antagonist 14871277 no
brompheniramine Anti-Allergic hrh1_human primary Class A (Rhodopsin) Histamine receptors approved 4 - 1957 small molecule antagonist 1680053 | 1970615 | 7714410 | 7855217 | 10212017 | 11752352 yes
buclizine Antiemetics acm1_human primary Class A (Rhodopsin) Acetylcholine receptors (muscarinic) approved 4 - 1982 small molecule antagonist 17139284 | 17016423 no
buclizine Antiemetics hrh1_human primary Class A (Rhodopsin) Histamine receptors approved 4 - 1982 small molecule antagonist 17139284 | 17016423 | 11752352 no
bupranolol Antihypertensive adrb1_human primary Class A (Rhodopsin) Adrenoceptors approved 4 - - small molecule antagonist 19439807 no
buserelin LHRH analogue gnrhr_human primary Class A (Rhodopsin) Gonadotrophin-releasing hormone receptors approved 4 - - peptide not available 20053189 yes
buprenorphine Anti-depressant; Analgesics; opioid addiction oprm_human primary Class A (Rhodopsin) Opioid receptors approved 4 - 1981 small molecule agonist 10729371 | 10942856 | 11275413 | 12435410 | 15100703 | 11752352 yes
buprenorphine Anti-depressant; Analgesics; opioid addiction oprm_human primary Class A (Rhodopsin) Opioid receptors approved 4 - 2016 small molecule agonist 10729371 | 10942856 | 11275413 | 12435410 | 15100703 | 11752352 yes
buspirone Anti-anxiety 5ht1a_human primary Class A (Rhodopsin) 5-Hydroxytryptamine receptors approved 4 - 1986 small molecule partial agonist 10027850 | 10064829 | 10215901 | 10221756 | 10428422 | 11752352 | 14769835 yes
buprenorphine Anti-depressant; Analgesics; opioid addiction oprk_human primary Class A (Rhodopsin) Opioid receptors approved 4 - 2016 small molecule agonist 17244875 | 16953647 yes
buspirone Anti-anxiety drd2_human primary Class A (Rhodopsin) Dopamine receptors approved 4 - 1986 small molecule partial agonist 12781354 | 11421254 | 11224194 | 14522358 | 16214127 yes
butorphanol Analgesics oprk_human primary Class A (Rhodopsin) Opioid receptors approved 4 - 1978 small molecule partial agonist 10381785 | 10779697 | 12127012 | 12470863 | 15942128 | 8968334 | 8746803 | 7705457 | 2555580 | 17909753 no
buprenorphine Anti-depressant; Analgesics; opioid addiction oprk_human primary Class A (Rhodopsin) Opioid receptors approved 4 - 1981 small molecule agonist 17244875 | 16953647 yes
butorphanol Analgesics oprm_human primary Class A (Rhodopsin) Opioid receptors approved 4 - 1978 small molecule partial agonist 10381785 | 12127012 | 12470863 | 15942128 | 8968334 | 8746803 | 9399970 | 7705457 | 17909753 no
butorphanol Analgesics oprd_human primary Class A (Rhodopsin) Opioid receptors approved 4 - 1978 small molecule partial agonist 12127012 | 12470863 | 15942128 | 8968334 | 8746803 | 7705457 | 17909753 | 11752352 no
cabergoline Antiparkinson drd2_human primary Class A (Rhodopsin) Dopamine receptors approved 4 - 1996 small molecule agonist 11752352 | 12464354 | 12008749 | 12721865 | 15341508 | 8951172 | 11436517 | 18303487 yes
butriptyline Anti-depressant 5ht2a_human primary Class A (Rhodopsin) 5-Hydroxytryptamine receptors approved 4 - 1974 small molecule antagonist 6086881 | 3816971 | 9537821 no
butriptyline Anti-depressant hrh1_human primary Class A (Rhodopsin) Histamine receptors approved 4 - 1974 small molecule antagonist 6086881 | 3816971 | 9537821 no
caffeine Central Nervous System Stimulants aa1r_human primary Class A (Rhodopsin) Adenosine receptors approved 4 - 1999 small molecule antagonist 16702031 | 17372967 | 17126319 | 17162470 | 17085856 | 11752352 yes
caffeine Central Nervous System Stimulants aa2ar_human primary Class A (Rhodopsin) Adenosine receptors approved 4 - 1999 small molecule antagonist 17558310 | 17577101 | 17616786 | 11752352 yes
calcitonin human parathyroid disease calcr_human primary Class B1 (Secretin) Calcitonin receptors approved 4 - 1986 peptide agonist 22461211 no
calcitonin salmon recombinant Paget's disease calcr_human primary Class B1 (Secretin) Calcitonin receptors approved 4 - 2005 peptide agonist 7610922 no
calcitonin salmon recombinant osteitis deformans calcr_human primary Class B1 (Secretin) Calcitonin receptors approved 4 - 2005 peptide agonist 7610922 no
calcitonin salmon recombinant postmenopausal osteoporosis calcr_human primary Class B1 (Secretin) Calcitonin receptors approved 4 - 1978 peptide agonist 7610922 no
candesartan cilexetil Antihypertensive agtr1_human primary Class A (Rhodopsin) Angiotensin receptors approved 4 - 1998 small molecule antagonist 19436650 | 17588300 yes
cangrelor antithrombotic p2y12_human primary Class A (Rhodopsin) P2Y receptors approved 4 - 2015 small molecule antagonist 26402735 no
captodiame anxiolytic drd3_human primary Class A (Rhodopsin) Dopamine receptors approved 4 - - small molecule agonist 23863923 no
captodiame anxiolytic 5ht2c_human primary Class A (Rhodopsin) 5-Hydroxytryptamine receptors approved 4 - - small molecule antagonist 23863923 no
carbachol Antiglaucomic acm1_human primary Class A (Rhodopsin) Acetylcholine receptors (muscarinic) approved 4 - 1972 small molecule agonist 15059034 no
carbachol Antiglaucomic acm2_human primary Class A (Rhodopsin) Acetylcholine receptors (muscarinic) approved 4 - 1972 small molecule agonist 15485827 | 15333678 | 12948933 | 12505062 | 16181410 no
carbinoxamine Anti-Allergic hrh1_human primary Class A (Rhodopsin) Histamine receptors approved 4 - 2003 small molecule antagonist 7513381 | 16574052 | 1143714 | 19761204 | 11752352 no
carboprost tromethamine Abortifacient pe2r1_human primary Class A (Rhodopsin) Prostanoid receptors approved 4 - 1965 small molecule agonist 17016423 | 20519365 | 11338376 | 9462300 no
cevimeline Parasympathomimetics acm3_human primary Class A (Rhodopsin) Acetylcholine receptors (muscarinic) approved 4 - 2000 small molecule agonist 17139284 | 17016423 | 18450949 | 11752352 no
cariprazine schizophrenia drd2_human primary Class A (Rhodopsin) Dopamine receptors approved 4 - 2015 small molecule partial agonist 23320989 no
cariprazine schizophrenia drd3_human primary Class A (Rhodopsin) Dopamine receptors approved 4 - 2015 small molecule partial agonist 23320989 no
carphenazine schizophrenia drd1_human primary Class A (Rhodopsin) Dopamine receptors approved 4 - 1982 small molecule antagonist 4889058 | 4887393 | 4861216 no
carphenazine schizophrenia drd5_human primary Class A (Rhodopsin) Dopamine receptors approved 4 - 1982 small molecule antagonist 4889058 | 4887393 | 4861216 no
carphenazine schizophrenia drd2_human primary Class A (Rhodopsin) Dopamine receptors approved 4 - 1982 small molecule antagonist 4889058 | 4887393 | 4861216 | 11752352 no
carteolol Antiglaucomic adrb1_human primary Class A (Rhodopsin) Adrenoceptors approved 4 - 1988 small molecule antagonist 11752352 | 15526107 | 10864881 | 16160085 yes
carteolol cardiovascular disease adrb2_human primary Class A (Rhodopsin) Adrenoceptors approved 4 - 1988 small molecule antagonist 1349493 | 15526107 | 11752352 yes
carvedilol cardiovascular disease adrb1_human primary Class A (Rhodopsin) Adrenoceptors approved 4 - 1995 small molecule antagonist 1712335 | 2575762 | 2577144 | 7908256 yes
carvedilol congestive heart failure ada1a_human primary Class A (Rhodopsin) Adrenoceptors approved 4 - 1995 small molecule antagonist 17139284 | 17016423 yes
celiprolol Antihypertensive adrb2_human primary Class A (Rhodopsin) Adrenoceptors approved 4 - - small molecule agonist 17141277 yes
celiprolol Antihypertensive adrb1_human primary Class A (Rhodopsin) Adrenoceptors approved 4 - - small molecule antagonist 17384462 | 17141277 | 18636069 yes
ceruletide, caerulein Diagnostic cckar_human primary Class A (Rhodopsin) Cholecystokinin receptors withdrawn 4 - 1982 small molecule agonist 2087492 | 1620654 | 8182534 | 1356589 | 2587420 | 3440035 no
cetirizine Anti-Allergic hrh1_human primary Class A (Rhodopsin) Histamine receptors approved 4 - 2007 small molecule antagonist 11752352 | 12787835 | 15286093 | 14505791 | 10597865 | 15942272 yes
cetrorelix Antineoplastic gnrhr_human primary Class A (Rhodopsin) Gonadotrophin-releasing hormone receptors approved 4 - 2000 peptide antagonist 11854630 | 12606421 | 14561652 | 14605254 | 16809153 | 11752352 yes
cevimeline Parasympathomimetics acm1_human primary Class A (Rhodopsin) Acetylcholine receptors (muscarinic) approved 4 - 2000 small molecule agonist 17139284 | 17016423 | 8624083 no
chlophedianol Antitussive hrh1_human primary Class A (Rhodopsin) Histamine receptors approved 4 - 1987 small molecule antagonist 2905706 no
chlorcyclizine Anti-Allergic hrh1_human primary Class A (Rhodopsin) Histamine receptors approved 4 - - small molecule antagonist 21058326 no
chloropyramine Anti-Allergic hrh1_human primary Class A (Rhodopsin) Histamine receptors approved 4 - - small molecule antagonist 19610651 no
chlorpheniramine Anti-Allergic hrh1_human primary Class A (Rhodopsin) Histamine receptors approved 4 - 1950 small molecule antagonist 11736858 no
chlorpromazine psychosis 5ht2a_human primary Class A (Rhodopsin) 5-Hydroxytryptamine receptors approved 4 - 1957 small molecule antagonist 10821438 | 8593484 yes
chlorpromazine psychosis drd2_human primary Class A (Rhodopsin) Dopamine receptors approved 4 - 1957 small molecule antagonist 11103886 | 11873706 | 15694263 | 16867246 | 11752352 | 20643630 | 7908055 | 8524985 yes
chlorprothixene schizophrenia 5ht2a_human primary Class A (Rhodopsin) 5-Hydroxytryptamine receptors approved 4 - 1967 small molecule antagonist 3774629 | 2891550 yes
chlorprothixene schizophrenia 5ht2b_human primary Class A (Rhodopsin) 5-Hydroxytryptamine receptors approved 4 - 1967 small molecule antagonist 17139284 | 17016423 yes
chlorprothixene schizophrenia 5ht2c_human primary Class A (Rhodopsin) 5-Hydroxytryptamine receptors approved 4 - 1967 small molecule antagonist 17139284 | 17016423 yes
chlorprothixene schizophrenia drd1_human primary Class A (Rhodopsin) Dopamine receptors approved 4 - 1967 small molecule antagonist 17139284 | 17016423 | 1830565 yes
chlorprothixene schizophrenia drd3_human primary Class A (Rhodopsin) Dopamine receptors approved 4 - 1967 small molecule antagonist 17139284 | 17016423 | 1830565 yes
chlorprothixene schizophrenia drd2_human primary Class A (Rhodopsin) Dopamine receptors approved 4 - 1967 small molecule antagonist 8101879 | 1830565 | 19091563 | 11752352 yes
chorionic gonadotropin Antineoplastic lshr_human primary Class A (Rhodopsin) Glycoprotein hormone receptors approved 4 - 1973 protein agonist 20836886 no
chorionic gonadotropin stroke lshr_human primary Class A (Rhodopsin) Glycoprotein hormone receptors approved 4 - 1973 protein agonist 20836886 no
chorionic gonadotropin Fertility lshr_human primary Class A (Rhodopsin) Glycoprotein hormone receptors approved 4 - 1973 protein agonist 20836886 no
cimetidine Antihistamines hrh2_human primary Class A (Rhodopsin) Histamine receptors approved 4 - 1977 small molecule antagonist 11752352 | 10950107 | 8863950 | 16723495 yes
cimetidine GI Anti-Ulcer ; antihistamines hrh2_human primary Class A (Rhodopsin) Histamine receptors approved 4 - 1977 small molecule antagonist 11752352 | 10950107 | 8863950 | 16723495 yes
cinacalcet hyperparathyroidism casr_human primary Class C (Glutamate) Calcium-sensing receptors approved 4 - 2004 small molecule PAM 15794735 | 15864123 | 15884662 | 16030053 | 16109140 | 19461861 | 19261825 | 19181759 | 19056615 | 11752352 yes
cinacalcet Calcimimetics casr_human primary Class C (Glutamate) Calcium-sensing receptors approved 4 - 2004 small molecule PAM 15794735 | 15864123 | 15884662 | 16030053 | 16109140 | 19461861 | 19261825 | 19181759 | 19056615 | 11752352 yes
cinitapride gastrointestinal disorders 5ht2a_human primary Class A (Rhodopsin) 5-Hydroxytryptamine receptors approved 4 - - small molecule antagonist 9211565 | 9562338 no
cinitapride gastrointestinal disorders 5ht1a_human primary Class A (Rhodopsin) 5-Hydroxytryptamine receptors approved 4 - - small molecule agonist 9211565 | 9562338 no
cinnarizine Anti-Allergic hrh1_human primary Class A (Rhodopsin) Histamine receptors approved 4 - 1989 small molecule antagonist 11752352 | 2866055 yes
cisapride Parasympathomimetics 5ht4r_human primary Class A (Rhodopsin) 5-Hydroxytryptamine receptors approved 4 - 1993 small molecule agonist 10027842 | 10328995 | 10556228 | 11034583 | 11218067 | 11752352 no
clemastine Anti-Allergic hrh1_human primary Class A (Rhodopsin) Histamine receptors approved 4 - 1977 small molecule antagonist 11752352 | 2890562 | 6701456 | 6387510 | 1678430 | 7513381 | 4074605 | 6449094 | 1266718 | 8930778 yes
glucagon Antidiabetic glr_human primary Class B1 (Secretin) Glucagon receptor family approved 4 - 1960 peptide agonist 17623014 | 17620721 yes
clenbuterol Bronchodilator adrb2_human primary Class A (Rhodopsin) Adrenoceptors approved 4 - - small molecule agonist 11720783 | 12388476 | 1322047 | 1685013 | 17449161 | 11752352 no
clidinium GI Anti-Ulcer ; anticholinergic; Antispasmodics acm1_human primary Class A (Rhodopsin) Acetylcholine receptors (muscarinic) approved 4 - 2013 small molecule antagonist 17139284 | 17016423 | 11752352 no
clofedanol antitussive hrh1_human primary Class A (Rhodopsin) Histamine receptors approved 4 - 1987 small molecule antagonist 17139284 | 17016423 | 11752352 | 2905706 no
cyclobenzaprine Muscle Relaxants 5ht2a_human primary Class A (Rhodopsin) 5-Hydroxytryptamine receptors approved 4 - 1977 small molecule antagonist 12498911 | 8884233 no
clonidine diabetic neuropathy; ADHD; antimucositic ada2b_human primary Class A (Rhodopsin) Adrenoceptors approved 4 - 1974 small molecule agonist 28715875 yes
clonidine diabetic neuropathy; ADHD; antimucositic ada2c_human primary Class A (Rhodopsin) Adrenoceptors approved 4 - 1974 small molecule agonist 28715875 yes
clonidine diabetic neuropathy; ADHD; antimucositic ada2a_human primary Class A (Rhodopsin) Adrenoceptors approved 4 - 1974 small molecule agonist 11752127 | 12357167 | 15306201 | 14757140 | 12098614 yes
clopidogrel antiplatelet p2y12_human primary Class A (Rhodopsin) P2Y receptors approved 4 - 1997 small molecule antagonist 14668029 | 15199474 | 15269827 | 15291969 | 15308557 | 11752352 | 19463375 | 16835302 | 12615691 yes
clopidogrel antithrombotic p2y12_human primary Class A (Rhodopsin) P2Y receptors approved 4 - 1997 small molecule antagonist 14668029 | 15199474 | 15269827 | 15291969 | 15308557 | 11752352 | 19463375 | 16835302 | 12615691 yes
clozapine schizophrenia drd2_human primary Class A (Rhodopsin) Dopamine receptors approved 4 - 1989 small molecule antagonist 12769622 | 14575800 | 15286066 | 15781964 | 16040180 | 11752352 yes
clozapine schizophrenia 5ht2a_human primary Class A (Rhodopsin) 5-Hydroxytryptamine receptors approved 4 - 1989 small molecule antagonist 12973385 | 14530903 | 14687870 | 14751426 | 15037867 | 7520908 yes
cocaine local anesthetic drd3_human secondary Class A (Rhodopsin) Dopamine receptors approved 4 - 1982 small molecule agonist 15351386 yes
cocaine local anesthetic oprk_human secondary Class A (Rhodopsin) Opioid receptors approved 4 - 1982 small molecule agonist 15351386 | 2840298 yes
codeine Analgesics oprm_human primary Class A (Rhodopsin) Opioid receptors approved 4 - 2009 small molecule agonist 15509185 | 17620111 | 8306082 | 11752352 yes
codeine Analgesics oprd_human primary Class A (Rhodopsin) Opioid receptors approved 4 - 2009 small molecule agonist 16386786 | 7885194 | 12067475 | 8119316 | 2156065 | 11752352 yes
codeine Analgesics oprk_human primary Class A (Rhodopsin) Opioid receptors approved 4 - 2009 small molecule agonist 17139284 | 17016423 | 17620111 | 7885194 yes
conivaptan hyponatremia v2r_human primary Class A (Rhodopsin) Vasopressin and oxytocin receptors approved 4 - 2005 small molecule antagonist 11752352 | 15659304 | 16843091 | 17919259 | 17202666 | 17592003 | 19695403 | 16522696 | 19057376 | 20054444 | 17428103 | 19663609 no
conivaptan hyponatremia v1ar_human primary Class A (Rhodopsin) Vasopressin and oxytocin receptors approved 4 - 2005 small molecule antagonist 11752352 | 17919259 | 17202666 | 17592003 | 19695403 | 16522696 | 19057376 | 20054444 | 17428103 | 19663609 no
corticorelin ovine triflutate Diagnostic crfr1_human primary Class B1 (Secretin) Corticotropin-releasing factor receptors approved 4 - 1996 small molecule agonist 20809121 no
cosyntropin Diagnostic acthr_human primary Class A (Rhodopsin) Melanocortin receptors approved 4 - 1970 peptide agonist 15710205 | 2156274 | 20562554 | 11752352 no
cromolyn sodium, chromoglycate anti-allergenic gpr35_human primary Class A (Rhodopsin) Class A orphans approved 4 - 2000 small molecule agonist 20559017 no
cyclizine Antiemetics hrh1_human primary Class A (Rhodopsin) Histamine receptors approved 4 - 1982 small molecule antagonist 11752352 | 1983158 yes
cyclobenzaprine Anti-depressant 5ht2a_human primary Class A (Rhodopsin) 5-Hydroxytryptamine receptors approved 4 - 1977 small molecule antagonist 12498911 | 8884233 no
cyclopentolate Mydriatics acm1_human primary Class A (Rhodopsin) Acetylcholine receptors (muscarinic) approved 4 - 1974 small molecule antagonist 17139284 | 17016423 yes
cycrimine Antiparkinson acm1_human primary Class A (Rhodopsin) Acetylcholine receptors (muscarinic) approved 4 - 1982 small molecule antagonist 17139284 | 17016423 | 1267542 | 11752352 no
cyproheptadine Anti-Allergic ; Appetite Stimulant hrh1_human primary Class A (Rhodopsin) Histamine receptors approved 4 - 1961 small molecule antagonist 11752352 yes
cyproheptadine Anti-Allergic ; Appetite Stimulant 5ht2a_human primary Class A (Rhodopsin) 5-Hydroxytryptamine receptors approved 4 - 1961 small molecule antagonist 12233819 | 12498911 | 1358088 | 1403790 | 16418149 yes
danazol diabetic macular edema gnrhr_human primary Class A (Rhodopsin) Gonadotrophin-releasing hormone receptors approved 4 - 1976 small molecule agonist 14571621 | 3004220 | 14605254 | 2404115 yes
danazol Antiendometriosis ; Antineoplastic gnrhr_human primary Class A (Rhodopsin) Gonadotrophin-releasing hormone receptors approved 4 - 1976 small molecule agonist 14571621 | 3004220 | 14605254 | 2404115 yes
darifenacin overactive bladder acm3_human primary Class A (Rhodopsin) Acetylcholine receptors (muscarinic) approved 4 - 2004 small molecule antagonist 20395537 | 19416629 | 18046909 | 11752352 yes
dapiprazole opthalmological ada1b_human primary Class A (Rhodopsin) Adrenoceptors approved 4 - 1990 small molecule antagonist 17139284 | 17016423 no
dapiprazole opthalmological ada1d_human primary Class A (Rhodopsin) Adrenoceptors approved 4 - 1990 small molecule antagonist 17139284 | 17016423 no
dapiprazole opthalmological ada1a_human primary Class A (Rhodopsin) Adrenoceptors approved 4 - 1990 small molecule antagonist 17139284 | 17016423 | 9401944 no
degarelix Antineoplastic gnrhr_human primary Class A (Rhodopsin) Gonadotrophin-releasing hormone receptors approved 4 - 2008 small molecule antagonist 20110043 | 20053189 | 19450172 | 15705170 yes
desipramine Anti-depressant hrh1_human primary Class A (Rhodopsin) Histamine receptors approved 4 - 1964 small molecule antagonist 10467920 | 7855217 no
desloratadine Anti-Allergic hrh1_human primary Class A (Rhodopsin) Histamine receptors approved 4 - 2001 small molecule antagonist 15564772 | 7581058 | 8174605 | 11752352 | 18336052 | 17902729 | 12642846 | 18797058 yes
desmopressin Antidiuretic v1ar_human primary Class A (Rhodopsin) Vasopressin and oxytocin receptors approved 4 - 1978 peptide not available 10731046 | 10594321 | 8957254 | 15613460 yes
desmopressin Antidiuretic v1br_human primary Class A (Rhodopsin) Vasopressin and oxytocin receptors approved 4 - 1978 peptide not available 15613460 | 14971638 | 18655906 yes
desmopressin Antidiuretic v2r_human primary Class A (Rhodopsin) Vasopressin and oxytocin receptors approved 4 - 1978 peptide agonist 18761325 | 16333859 | 11752352 yes
dexbrompheniramine Anti-Allergic hrh1_human primary Class A (Rhodopsin) Histamine receptors approved 4 - 1963 small molecule antagonist 9691225 | 1680053 | 1970615 | 7714410 | 19085565 | 11752352 no
dexchlorpheniramine sunburn hrh1_human primary Class A (Rhodopsin) Histamine receptors approved 4 - 1981 small molecule antagonist 374215 no
dexmedetomidine Analgesics ada2b_human primary Class A (Rhodopsin) Adrenoceptors approved 4 - 1999 small molecule agonist 15306201 no
dexmedetomidine Antineoplastic ada2c_human primary Class A (Rhodopsin) Adrenoceptors approved 4 - 1999 small molecule agonist 15306201 no
dexmedetomidine Analgesics; Hypnotics and Sedatives ada2a_human primary Class A (Rhodopsin) Adrenoceptors approved 4 - 1999 small molecule agonist 11752127 | 11834617 | 14583739 | 15087625 | 15306201 | 17692748 no
dezocine Analgesics oprk_human primary Class A (Rhodopsin) Opioid receptors approved 4 - 1989 small molecule partial agonist 17139284 | 17016423 | 16433932 | 11752352 no
glucagon Antihypoglycemic glr_human primary Class B1 (Secretin) Glucagon receptor family approved 4 - 1960 peptide agonist 17623014 | 17620721 yes
dezocine Analgesics oprm_human primary Class A (Rhodopsin) Opioid receptors approved 4 - 1989 small molecule partial agonist 9399970 | 11702089 | 10958085 | 12513698 | 9972766 | 1361946 no
dicyclomine Antispasmodics acm1_human primary Class A (Rhodopsin) Acetylcholine receptors (muscarinic) approved 4 - 1950 small molecule antagonist 17139284 | 17016423 | 19533734 | 11752352 no
difenoxin recurrent infection of the gastrointestinal tract oprm_human primary Class A (Rhodopsin) Opioid receptors approved 4 - 1978 small molecule agonist 8386327 no
dihydrocodeine Analgesics oprm_human primary Class A (Rhodopsin) Opioid receptors approved 4 - 1958 small molecule agonist 12665158 yes
dihydroergotamine Anti-migraine 5ht1b_human primary Class A (Rhodopsin) 5-Hydroxytryptamine receptors approved 4 - 1997 small molecule agonist 10455274 | 14744615 | 1660351 | 8622623 | 9650800 no
dipivefrin Antiglaucomic adrb2_human primary Class A (Rhodopsin) Adrenoceptors approved 4 - 1980 small molecule agonist 11752352 | 17622774 | 17417877 | 17597612 yes
dihydroergotamine Anti-migraine 5ht1d_human primary Class A (Rhodopsin) 5-Hydroxytryptamine receptors approved 4 - 1997 small molecule agonist 11752352 | 9605573 | 1379707 | 1324091 | 12558771 | 1407010 | 14744615 no
dimenhydrinate Antiemetics hrh1_human primary Class A (Rhodopsin) Histamine receptors approved 4 - 1972 small molecule antagonist 11752352 | 11835984 yes
dimetindene Anti-Allergic acm2_human primary Class A (Rhodopsin) Acetylcholine receptors (muscarinic) approved 4 - - small molecule antagonist 8608784 no
dimetindene Anti-Allergic hrh1_human primary Class A (Rhodopsin) Histamine receptors approved 4 - - small molecule antagonist 20800486 | 8608784 no
dinoprost tromethamine Abortifacient pi2r_human primary Class A (Rhodopsin) Prostanoid receptors approved 4 - 1981 small molecule agonist 17139284 | 17016423 | 11752352 no
dinoprostone Abortifacient pe2r4_human primary Class A (Rhodopsin) Prostanoid receptors approved 4 - 1977 small molecule agonist 16545798 | 18715952 | 20599704 | 19788928 | 17329241 yes
dinoprostone Abortifacient pe2r1_human primary Class A (Rhodopsin) Prostanoid receptors approved 4 - 1977 small molecule agonist 18715952 | 20599704 | 19788928 | 17329241 yes
dinoprostone Abortifacient pe2r3_human primary Class A (Rhodopsin) Prostanoid receptors approved 4 - 1977 small molecule agonist 18715952 | 20599704 | 19788928 | 17329241 yes
dinoprostone Abortifacient pe2r2_human primary Class A (Rhodopsin) Prostanoid receptors approved 4 - 1977 small molecule agonist 18715952 | 20599704 | 19788928 | 17329241 | 11752352 yes
diphemanil Bronchodilator acm3_human primary Class A (Rhodopsin) Acetylcholine receptors (muscarinic) approved 4 - 1976 small molecule antagonist 6450282 no
diphenhydramine Anti-Allergic ; Hypnotics and sedatives; Antiemetics; Antipruritics; Antitussives hrh1_human primary Class A (Rhodopsin) Histamine receptors approved 4 - 1946 small molecule antagonist 11752352 | 17169617 | 16702624 | 17390763 | 17196194 | 17329841 | 2878016 yes
diphenidol Antiemetics acm2_human primary Class A (Rhodopsin) Acetylcholine receptors (muscarinic) approved 4 - 1967 small molecule antagonist 10497897 | 9851542 | 9454790 | 9059856 | 8050463 | 12185001 | 10530931 | 1863523 no
diphenidol Antiemetics acm3_human primary Class A (Rhodopsin) Acetylcholine receptors (muscarinic) approved 4 - 1967 small molecule antagonist 17139284 | 17016423 | 12185001 | 10530931 | 1863523 no
diphenidol Antiemetics acm1_human primary Class A (Rhodopsin) Acetylcholine receptors (muscarinic) approved 4 - 1967 small molecule antagonist 17139284 | 17016423 | 1863523 no
diphenoxylate Antidiuretic oprm_human primary Class A (Rhodopsin) Opioid receptors approved 4 - 1960 small molecule agonist 11752352 | 18192961 | 10202212 | 8583364 | 8386327 no
diphenylpyraline Anti-Allergic hrh1_human primary Class A (Rhodopsin) Histamine receptors approved 4 - 1982 small molecule antagonist 17139284 | 17016423 | 1912125 | 1678430 | 18977145 | 15627433 | 11752352 no
dipivefrin opthalmological ada2a_human primary Class A (Rhodopsin) Adrenoceptors approved 4 - 1980 small molecule agonist 17139284 | 17016423 yes
dipivefrin Antiglaucomic ada1a_human primary Class A (Rhodopsin) Adrenoceptors approved 4 - 1980 small molecule agonist 17603545 | 17658513 yes
dobutamine Cardiotonic adrb1_human primary Class A (Rhodopsin) Adrenoceptors approved 4 - 1978 small molecule agonist 12098582 | 15564877 | 16325050 | 16627864 | 11752352 no
dopamine hypotension adrb1_human primary Class A (Rhodopsin) Adrenoceptors approved 4 - 1974 small molecule agonist 23241039 no
doxepin Hypnotics and Sedatives hrh2_human primary Class A (Rhodopsin) Histamine receptors approved 4 - 1969 small molecule antagonist 2897127 | 2141000 yes
doxacurium Muscle Relaxants acm2_human primary Class A (Rhodopsin) Acetylcholine receptors (muscarinic) approved 4 - 1991 small molecule antagonist 9523819 no
doxazosin Anticholesteremic ; Antihypertensive ; Vasodilator ada1a_human primary Class A (Rhodopsin) Adrenoceptors approved 4 - 1990 small molecule antagonist 15573147 | 8736427 | 14767264 | 9205965 | 16225542 | 19002123 | 17070143 | 10393471 | 11752352 yes
doxazosin Anticholesteremic ; Antihypertensive ; Vasodilator ada1b_human primary Class A (Rhodopsin) Adrenoceptors approved 4 - 1990 small molecule antagonist 18231614 | 19002123 | 17070143 | 10393471 yes
doxazosin Anticholesteremic ; Antihypertensive ; Vasodilator ada1d_human primary Class A (Rhodopsin) Adrenoceptors approved 4 - 1990 small molecule antagonist 18231614 | 19002123 | 17070143 | 10393471 yes
doxepin Hypnotics and Sedatives hrh1_human primary Class A (Rhodopsin) Histamine receptors approved 4 - 1969 small molecule antagonist 15286093 | 7238574 | 15255990 | 3011460 | 6086881 | 7855217 | 19179941 | 17685877 | 2141000 | 11752352 yes
doxepin Hypnotics and Sedatives acm1_human primary Class A (Rhodopsin) Acetylcholine receptors (muscarinic) approved 4 - 1969 small molecule antagonist 7855217 | 19179941 | 2329499 | 2141000 yes
doxepin Hypnotics and Sedatives 5ht2a_human primary Class A (Rhodopsin) 5-Hydroxytryptamine receptors approved 4 - 1969 small molecule antagonist 7855217 | 309138 | 19179941 yes
doxepin Hypnotics and Sedatives acm2_human primary Class A (Rhodopsin) Acetylcholine receptors (muscarinic) approved 4 - 1969 small molecule antagonist 7855217 | 2329499 | 2141000 yes
doxepin Hypnotics and Sedatives acm3_human primary Class A (Rhodopsin) Acetylcholine receptors (muscarinic) approved 4 - 1969 small molecule antagonist 7855217 | 2329499 | 2141000 yes
doxepin Hypnotics and Sedatives acm4_human primary Class A (Rhodopsin) Acetylcholine receptors (muscarinic) approved 4 - 1969 small molecule antagonist 7855217 | 2329499 | 2141000 yes
doxepin Hypnotics and Sedatives acm5_human primary Class A (Rhodopsin) Acetylcholine receptors (muscarinic) approved 4 - 1969 small molecule antagonist 7855217 | 2329499 | 2141000 yes
doxylamine Antihistamine; for nausea and vomiting of pregnancy hrh1_human primary Class A (Rhodopsin) Histamine receptors approved 4 - 1948 small molecule antagonist 17139284 | 17016423 | 11752352 no
doxepin Hypnotics and Sedatives 5ht2b_human primary Class A (Rhodopsin) 5-Hydroxytryptamine receptors approved 4 - 1969 small molecule antagonist 7855217 | 309138 yes
doxepin Hypnotics and Sedatives 5ht2c_human primary Class A (Rhodopsin) 5-Hydroxytryptamine receptors approved 4 - 1969 small molecule antagonist 7855217 | 309138 yes
doxylamine Anti-Allergic ; Antiemetics; Antitussive ; Hypnotics and Sedatives hrh1_human primary Class A (Rhodopsin) Histamine receptors approved 4 - 1948 small molecule antagonist 17139284 | 17016423 | 11752352 no
dronabinol Analgesics cnr1_human primary Class A (Rhodopsin) Cannabinoid receptors approved 4 - 1985 small molecule agonist 17139284 | 17016423 | 12686391 | 11204352 | 11752352 no
dronabinol Appetite stimulant cnr1_human primary Class A (Rhodopsin) Cannabinoid receptors approved 4 - 1985 small molecule agonist 17139284 | 17016423 | 12686391 | 11204352 | 11752352 no
droperidol psychosis 5ht2a_human primary Class A (Rhodopsin) 5-Hydroxytryptamine receptors approved 4 - 1970 small molecule antagonist 2527092 no
dronedarone Anti-Arrhythmia ada1a_human primary Class A (Rhodopsin) Adrenoceptors approved 4 - 2009 small molecule antagonist 17389667 yes
dronedarone Anti-Arrhythmia adrb1_human primary Class A (Rhodopsin) Adrenoceptors approved 4 - 2009 small molecule antagonist 17389667 yes
droperidol Adjuvants; Anesthesia drd2_human primary Class A (Rhodopsin) Dopamine receptors approved 4 - 1970 small molecule antagonist 1549935 | 2527092 | 14633536 | 20358234 no
droxidopa orthostatic hypotension ada1a_human primary Class A (Rhodopsin) Adrenoceptors approved 4 - 2014 small molecule agonist 11482743 | 17266602 | 20412040 | 9138687 | 8825367 no
droxidopa orthostatic hypotension ada1d_human primary Class A (Rhodopsin) Adrenoceptors approved 4 - 2014 small molecule agonist 17266602 | 20412040 | 7582530 | 7674815 no
droxidopa orthostatic hypotension ada1b_human primary Class A (Rhodopsin) Adrenoceptors approved 4 - 2014 small molecule agonist 17266602 | 20412040 | 7773533 | 8166240 no
droxidopa orthostatic hypotension adrb3_human primary Class A (Rhodopsin) Adrenoceptors approved 4 - 2014 small molecule agonist 19434307 | 9464897 | 19110970 | 18064417 no
droxidopa orthostatic hypotension ada2a_human primary Class A (Rhodopsin) Adrenoceptors approved 4 - 2014 small molecule agonist 21173850 | 18680204 | 11306720 no
droxidopa orthostatic hypotension ada2b_human primary Class A (Rhodopsin) Adrenoceptors approved 4 - 2014 small molecule agonist 21173850 | 18680204 | 18064417 no
droxidopa orthostatic hypotension ada2c_human primary Class A (Rhodopsin) Adrenoceptors approved 4 - 2014 small molecule agonist 21173850 | 18680204 | 8590979 no
droxidopa orthostatic hypotension adrb1_human primary Class A (Rhodopsin) Adrenoceptors approved 4 - 2014 small molecule agonist 9464897 | 19110970 | 18064417 no
droxidopa orthostatic hypotension adrb2_human primary Class A (Rhodopsin) Adrenoceptors approved 4 - 2014 small molecule agonist 9464897 | 9666280 | 7969507 | 19110970 | 18064417 no
dulaglutide Antidiabetic glp1r_human primary Class B1 (Secretin) Glucagon receptor family approved 4 - 2014 protein agonist 25367716 yes
eletriptan Anti-migraine 5ht1b_human primary Class A (Rhodopsin) 5-Hydroxytryptamine receptors approved 4 - 2002 small molecule agonist 10193663 | 11050304 | 11069595 | 11513839 | 12384251 | 11752352 yes
eletriptan Anti-migraine 5ht1f_human primary Class A (Rhodopsin) 5-Hydroxytryptamine receptors approved 4 - 2002 small molecule agonist 10193663 | 11834243 | 15185063 yes
eletriptan Anti-migraine 5ht1d_human primary Class A (Rhodopsin) 5-Hydroxytryptamine receptors approved 4 - 2002 small molecule agonist 11752352 | 10193663 | 15821444 | 11513839 | 12498013 | 11152011 yes
eluxadoline irritable bowel syndrome oprd_human primary Class A (Rhodopsin) Opioid receptors approved 4 - 2015 small molecule agonist 25261794 no
eluxadoline irritable bowel syndrome oprm_human primary Class A (Rhodopsin) Opioid receptors approved 4 - 2015 small molecule agonist 25261794 | 23583433 no
emedastine Anti-Allergic hrh1_human primary Class A (Rhodopsin) Histamine receptors approved 4 - 1997 small molecule antagonist 7714409 | 7714410 | 9747899 | 19558341 | 15553105 | 18714531 | 11752352 yes
ephedrine Central Nervous System Stimulants ada1a_human primary Class A (Rhodopsin) Adrenoceptors approved 4 - 1963 small molecule not available 17405867 | 12557268 | 10592235 yes
epinastine Anti-Allergic hrh2_human primary Class A (Rhodopsin) Histamine receptors approved 4 - 2003 small molecule antagonist 16131920 yes
epinastine Anti-Allergic hrh1_human primary Class A (Rhodopsin) Histamine receptors approved 4 - 2003 small molecule antagonist 17534605 | 1972625 | 11752352 yes
epinephrine, adrenaline Anesthetics ada2a_human primary Class A (Rhodopsin) Adrenoceptors approved 4 - 1976 small molecule agonist 11306720 | 10742288 | 9836297 | 1980236 | 18680204 | 18064417 no
epinephrine, adrenaline Anesthetics adrb2_human primary Class A (Rhodopsin) Adrenoceptors approved 4 - 1976 small molecule agonist 11752352 | 17622774 | 17417877 | 17597612 no
epinephrine, adrenaline Anesthetics adrb1_human primary Class A (Rhodopsin) Adrenoceptors approved 4 - 1976 small molecule agonist 11752352 | 17622774 | 17541557 no
epinephrine, adrenaline Anesthetics ada1a_human primary Class A (Rhodopsin) Adrenoceptors approved 4 - 1976 small molecule agonist 17603545 | 17658513 | 20412040 | 20857090 no
epinephrine, adrenaline Anesthetics ada2b_human primary Class A (Rhodopsin) Adrenoceptors approved 4 - 1976 small molecule agonist 1979424 | 11728431 | 11053214 | 1980236 | 18064417 no
epinephrine, adrenaline Anesthetics ada1b_human primary Class A (Rhodopsin) Adrenoceptors approved 4 - 1976 small molecule agonist 20954794 | 19730427 | 20412040 | 20857090 no
epoprostenol Antihypertensive ; Platelet Aggregation Inhibitors pi2r_human primary Class A (Rhodopsin) Prostanoid receptors approved 4 - 1995 small molecule agonist 19302827 | 12297509 | 20522800 | 11752352 yes
eprosartan Antihypertensive agtr1_human primary Class A (Rhodopsin) Angiotensin receptors approved 4 - 1997 small molecule antagonist 11752352 | 12927226 | 10856732 | 12540520 | 9602957 | 12782193 | 12184062 | 12766389 | 12517247 | 18093407 | 11320369 yes
ergoloid, co-dergocrine mesilate cardiovascular disease ada1b_human primary Class A (Rhodopsin) Adrenoceptors approved 4 - 1953 small molecule agonist 8786706 | 2869188 no
ergoloid, co-dergocrine mesilate cardiovascular disease ada1d_human primary Class A (Rhodopsin) Adrenoceptors approved 4 - 1953 small molecule agonist 8786706 | 2869188 no
ergoloid cardiovascular disease ada2b_human primary Class A (Rhodopsin) Adrenoceptors approved 4 - 1953 small molecule agonist 8786706 | 2869188 yes
ergoloid cardiovascular disease ada2c_human primary Class A (Rhodopsin) Adrenoceptors approved 4 - 1953 small molecule agonist 8786706 | 2869188 yes
esmolol Anti-Arrhythmia adrb1_human primary Class A (Rhodopsin) Adrenoceptors approved 4 - 1986 small molecule antagonist 11752352 | 7612051 | 7957532 | 2568748 | 2894187 | 1975995 no
ergoloid Nootropic ; Vasodilator ada1a_human primary Class A (Rhodopsin) Adrenoceptors approved 4 - 1953 small molecule agonist 8786706 | 2869188 yes
ergoloid Nootropic ; Vasodilator ada2a_human primary Class A (Rhodopsin) Adrenoceptors approved 4 - 1953 small molecule agonist 8786706 | 2869188 yes
ergonovine, ergometrine antihaemorrhagic ada1a_human primary Class A (Rhodopsin) Adrenoceptors approved 4 - 1946 small molecule agonist 2897449 | 19933260 no
ergotamine Anti-migraine ada1b_human primary Class A (Rhodopsin) Adrenoceptors approved 4 - 1960 small molecule agonist 18066532 yes
ergotamine Anti-migraine ada1d_human primary Class A (Rhodopsin) Adrenoceptors approved 4 - 1960 small molecule agonist 18066532 yes
ergotamine Anti-migraine ada2c_human primary Class A (Rhodopsin) Adrenoceptors approved 4 - 1960 small molecule agonist 18066532 yes
ergotamine Anti-migraine 5ht1b_human primary Class A (Rhodopsin) 5-Hydroxytryptamine receptors approved 4 - 1960 small molecule agonist 10188968 | 10455274 | 11015308 | 15224175 yes
ergotamine Anti-migraine 5ht1d_human primary Class A (Rhodopsin) 5-Hydroxytryptamine receptors approved 4 - 1960 small molecule agonist 12558771 | 8384716 | 1407010 | 14504136 | 1646776 yes
ergotamine Anti-migraine ada2b_human primary Class A (Rhodopsin) Adrenoceptors approved 4 - 1960 small molecule agonist 17139284 | 17016423 yes
ergotamine Anti-migraine ada1a_human primary Class A (Rhodopsin) Adrenoceptors approved 4 - 1960 small molecule agonist 17139284 | 17016423 | 18066532 yes
ergotamine Anti-migraine ada2a_human primary Class A (Rhodopsin) Adrenoceptors approved 4 - 1960 small molecule agonist 17139284 | 17016423 | 18066532 yes
etelcalcetide, amg 416, velcalcetide, kai-4169, ono-5163 parathyroid disorders casr_human primary Class C (Glutamate) Calcium-sensing receptors approved 4 - 2017 peptide agonist 24235081 no
ethopropazine Antidyskinetics acm1_human primary Class A (Rhodopsin) Acetylcholine receptors (muscarinic) approved 4 - 1982 small molecule antagonist 17016423 | 2904117 | 2236897 | 11752352 no
ethylmorphine Analgesics oprm_human primary Class A (Rhodopsin) Opioid receptors approved 4 - - small molecule agonist 16530171 | 16580639 | 16580848 | 16682505 | 11752352 no
etomidate Anesthetics; Intravenous ada2b_human primary Class A (Rhodopsin) Adrenoceptors approved 4 - 1982 small molecule PAM 20496522 | 14508322 yes
exenatide Antidiabetic glp1r_human primary Class B1 (Secretin) Glucagon receptor family approved 4 - 2005 peptide agonist 16722815 | 17292977 | 17353295 | 16534527 | 17379930 | 20649595 | 15331551 | 15495988 | 15700891 | 16341288 | 16627399 | 11752352 yes
exendin-4 Antidiabetic glp1r_human primary Class B1 (Secretin) Glucagon receptor family approved 4 - 2005 peptide agonist 16374859 no
famotidine acid reducer hrh2_human primary Class A (Rhodopsin) Histamine receptors approved 4 - 1986 small molecule antagonist 11752352 | 17273750 | 16723495 | 16702624 | 16513821 | 12832840 | 12509588 | 2067140 | 1646056 | 19578661 | 18310651 yes
famotidine gastric ulcer and gastroesophageal reflux hrh2_human primary Class A (Rhodopsin) Histamine receptors approved 4 - 1986 small molecule antagonist 11752352 | 17273750 | 16723495 | 16702624 | 16513821 | 12832840 | 12509588 | 2067140 | 1646056 | 19578661 | 18310651 yes
fenoldopam Antihypertensive drd1_human primary Class A (Rhodopsin) Dopamine receptors approved 4 - 1997 small molecule agonist 11752352 | 19293728 | 8103596 no
fenoldopam Antihypertensive drd5_human primary Class A (Rhodopsin) Dopamine receptors approved 4 - 1997 small molecule agonist 17139284 | 17016423 | 19293728 | 8103596 no
fenoterol Bronchodilator ; Tocolytic adrb2_human primary Class A (Rhodopsin) Adrenoceptors approved 4 withdrawn - small molecule agonist 11730729 | 16324695 | 6203844 | 8777955 | 8911881 | 11752352 yes
fentanyl adjuvant to anesthesia oprm_human primary Class A (Rhodopsin) Opioid receptors approved 4 - 1968 small molecule agonist 15589524 | 16114980 | 16332149 | 16376082 | 16797997 | 11752352 | 19403616 yes
fingolimod Multiple Sclerosis s1pr1_human primary Class A (Rhodopsin) Lysophospholipid (S1P) receptors approved 4 - 2010 small molecule agonist 16374859 yes
fingolimod Multiple Sclerosis s1pr5_human primary Class A (Rhodopsin) Lysophospholipid (S1P) receptors approved 4 - 2010 small molecule agonist 23579459 | 23579456 yes
flavoxate Antispasmodics acm2_human primary Class A (Rhodopsin) Acetylcholine receptors (muscarinic) approved 4 - 1970 small molecule antagonist 17139284 | 17016423 | 19002123 | 10858873 | 3247311 yes
flavoxate Antispasmodics acm1_human primary Class A (Rhodopsin) Acetylcholine receptors (muscarinic) approved 4 - 1970 small molecule antagonist 17139284 | 17016423 | 3247311 yes
fentanyl Analgesics oprm_human primary Class A (Rhodopsin) Opioid receptors approved 4 - 1968 small molecule agonist 15589524 | 16114980 | 16332149 | 16376082 | 16797997 | 11752352 | 19403616 yes
flibanserin sexual dysfunction 5ht1a_human primary Class A (Rhodopsin) 5-Hydroxytryptamine receptors approved 4 - 2015 small molecule agonist 12890707 | 12177684 | 26412054 no
fentanyl adjuvant to anesthesia oprd_human primary Class A (Rhodopsin) Opioid receptors approved 4 - 1968 small molecule agonist 15665994 | 15828941 | 15868528 | 16372825 | 16861092 | 19403616 yes
flunarizine Anticonvulsants; Vasodilator hrh1_human primary Class A (Rhodopsin) Histamine receptors approved 4 - 1968 small molecule antagonist 17139284 | 17016423 | 20493137 yes
flupentixol Antipsychotic acm1_human primary Class A (Rhodopsin) Acetylcholine receptors (muscarinic) approved 4 - 1965 small molecule antagonist 7052344 yes
flupentixol Antipsychotic 5ht2a_human primary Class A (Rhodopsin) 5-Hydroxytryptamine receptors approved 4 - 1965 small molecule antagonist 17111172 yes
flupentixol Antipsychotic drd2_human primary Class A (Rhodopsin) Dopamine receptors approved 4 - 1965 small molecule antagonist 11752352 | 11873706 | 6149133 | 7498321 | 1674528 | 8797192 | 17111172 yes
fentanyl Analgesics oprd_human primary Class A (Rhodopsin) Opioid receptors approved 4 - 1968 small molecule agonist 15665994 | 15828941 | 15868528 | 16372825 | 16861092 | 19403616 yes
fesoterodine prostate adenocarcinoma acm2_human primary Class A (Rhodopsin) Acetylcholine receptors (muscarinic) approved 4 - 2007 small molecule antagonist 19029429 yes
fesoterodine overactive bladder syndrome acm3_human primary Class A (Rhodopsin) Acetylcholine receptors (muscarinic) approved 4 - 2007 small molecule antagonist 11752352 | 12076307 yes
fexofenadine Anti-Allergic hrh1_human primary Class A (Rhodopsin) Histamine receptors approved 4 - 1996 small molecule antagonist 11752352 | 10864400 | 15352500 | 12712828 | 15286093 | 10597865 | 18336052 | 18797058 | 19545214 | 9506246 yes
flupentixol Antipsychotic drd1_human primary Class A (Rhodopsin) Dopamine receptors approved 4 - 1965 small molecule antagonist 17139284 | 17016423 | 10531405 | 17111172 yes
fluphenazine schizophrenia drd1_human primary Class A (Rhodopsin) Dopamine receptors approved 4 - 1959 small molecule antagonist 11752352 | 11113312 | 10531405 | 11873706 yes
fluphenazine schizophrenia drd2_human primary Class A (Rhodopsin) Dopamine receptors approved 4 - 1959 small molecule antagonist 11873706 | 7508675 | 7828655 | 11752352 yes
fluphenazine decanoate psychosis drd2_human primary Class A (Rhodopsin) Dopamine receptors approved 4 - 1972 small molecule antagonist 7828655 yes
fluphenazine enanthate psychosis drd2_human primary Class A (Rhodopsin) Dopamine receptors approved 4 - 1967 small molecule antagonist 7828655 no
fluspirilene schizophrenia drd2_human primary Class A (Rhodopsin) Dopamine receptors approved 4 - 1977 small molecule antagonist 17139284 | 17016423 | 11752352 | 11842444 | 8935801 no
formoterol Anti-Asthmatic adrb2_human primary Class A (Rhodopsin) Adrenoceptors approved 4 - 2010 small molecule agonist 12090787 | 14662724 | 16432501 | 2544117 | 7675115 | 11752352 | 9506248 | 14720051 | 18686730 | 1718682 | 17594727 yes
follitropin Fertility fshr_human primary Class A (Rhodopsin) Glycoprotein hormone receptors approved 4 - 1997 protein agonist 11299519 | 7755615 | 2108722 | 8319832 | 8070368 | 18020563 | 11752352 yes
forasartan Antihypertensive agtr1_human primary Class A (Rhodopsin) Angiotensin receptors approved 4 - - small molecule antagonist 11569611 | 8981065 | 9156352 | 11752352 no
formoterol Anti-Asthmatic adrb2_human primary Class A (Rhodopsin) Adrenoceptors approved 4 - 2001 small molecule agonist 12090787 | 14662724 | 16432501 | 2544117 | 7675115 | 11752352 | 9506248 | 14720051 | 18686730 | 1718682 | 17594727 yes
formoterol chronic obstructive pulmonary disease (COPD) adrb2_human primary Class A (Rhodopsin) Adrenoceptors approved 4 - 2016 small molecule agonist 12090787 | 14662724 | 16432501 | 2544117 | 7675115 | 11752352 | 9506248 | 14720051 | 18686730 | 1718682 | 17594727 yes
formoterol chronic obstructive pulmonary disease (COPD) adrb2_human primary Class A (Rhodopsin) Adrenoceptors approved 4 - 2001 small molecule agonist 12090787 | 14662724 | 16432501 | 2544117 | 7675115 | 11752352 | 9506248 | 14720051 | 18686730 | 1718682 | 17594727 yes
formoterol Bronchodilator adrb2_human primary Class A (Rhodopsin) Adrenoceptors approved 4 - 2001 small molecule agonist 12090787 | 14662724 | 16432501 | 2544117 | 7675115 | 11752352 | 9506248 | 14720051 | 18686730 | 1718682 | 17594727 yes
formoterol Anti-Asthmatic ; COPD adrb2_human primary Class A (Rhodopsin) Adrenoceptors approved 4 - 2001 small molecule agonist 12090787 | 14662724 | 16432501 | 2544117 | 7675115 | 11752352 | 9506248 | 14720051 | 18686730 | 1718682 | 17594727 yes
frovatriptan Anti-migraine 5ht1d_human primary Class A (Rhodopsin) 5-Hydroxytryptamine receptors approved 4 - 2001 small molecule agonist 11752352 | 11735616 | 12028320 | 11152011 | 10883409 | 15185063 | 15311727 | 9700983 | 18360605 | 15342617 | 12028322 yes
frovatriptan Anti-migraine 5ht1b_human primary Class A (Rhodopsin) 5-Hydroxytryptamine receptors approved 4 - 2001 small molecule agonist 11752352 | 15311727 | 12028320 | 9700983 | 11735616 | 17190530 | 11152011 | 10883409 | 18001261 | 18360605 | 15342617 | 12028322 yes
gamma hydroxybutyric acid Hypnotics and Sedatives gabr1_human primary Class C (Glutamate) GABAB receptors approved 4 - 2002 small molecule agonist 15745703 no
gamma hydroxybutyric acid Hypnotics and Sedatives gabr2_human primary Class C (Glutamate) GABAB receptors approved 4 - 2002 small molecule agonist 15745703 no
ganirelix acetate for prevention of premature ovulation in fertility treatment gnrhr_human primary Class A (Rhodopsin) Gonadotrophin-releasing hormone receptors approved 4 - 1999 small molecule antagonist 15932933 no
ganirelix acetate Fertility gnrhr_human primary Class A (Rhodopsin) Gonadotrophin-releasing hormone receptors approved 4 - 1999 small molecule antagonist 15932933 no
glucagon for prevention of hypoglycemia glr_human primary Class B1 (Secretin) Glucagon receptor family approved 4 - 1960 peptide agonist 17623014 | 17620721 yes
glucagon hypoglycemia glr_human primary Class B1 (Secretin) Glucagon receptor family approved 4 - 1998 peptide agonist 17623014 | 17620721 yes
glycopyrrolate Antineoplastic acm1_human primary Class A (Rhodopsin) Acetylcholine receptors (muscarinic) approved 4 - 1961 small molecule antagonist 8249551 no
hyoscyamine Antispasmodics acm1_human primary Class A (Rhodopsin) Acetylcholine receptors (muscarinic) approved 4 - - small molecule antagonist 17139284 | 17016423 | 9732369 no
glycopyrrolate chronic obstructive pulmonary disease (COPD) acm1_human primary Class A (Rhodopsin) Acetylcholine receptors (muscarinic) approved 4 - 1961 small molecule antagonist 8249551 no
glycopyrronium chronic obstructive pulmonary disease (COPD) adrb2_human primary Class A (Rhodopsin) Adrenoceptors approved 4 - 1961 small molecule antagonist 28767773 yes
gonadorelin Fertility gnrhr_human primary Class A (Rhodopsin) Gonadotrophin-releasing hormone receptors approved 4 - 1982 small molecule agonist 15967801 | 16962597 | 16973761 | 17002488 | 17068198 | 11752352 yes
goserelin Antineoplastic gnrhr_human primary Class A (Rhodopsin) Gonadotrophin-releasing hormone receptors approved 4 - 1989 peptide agonist 20053189 yes
goserelin Antineoplastic s; Hormonal lshr_human primary Class A (Rhodopsin) Glycoprotein hormone receptors approved 4 - 1989 peptide agonist 17139284 | 17016423 | 20053189 yes
guanabenz Antihypertensive ada2a_human primary Class A (Rhodopsin) Adrenoceptors approved 4 - 1982 small molecule agonist 8263811 | 7903385 | 8819507 | 15265636 | 9050980 no
guanfacine ADHD ada2a_human primary Class A (Rhodopsin) Adrenoceptors approved 4 - 1986 small molecule agonist 10942848 | 17173664 | 15928018 | 11164065 | 1356794 | 20331927 yes
haloperidol psychosis drd2_human primary Class A (Rhodopsin) Dopamine receptors approved 4 - 1986 small molecule antagonist 27578530 yes
haloperidol schizophrenia drd2_human primary Class A (Rhodopsin) Dopamine receptors approved 4 - 1967 small molecule antagonist 15894081 | 16132064 | 17134027 | 11752352 | 16730699 | 17316700 | 7520908 | 20643630 yes
hexocyclium digestive system disease acm1_human primary Class A (Rhodopsin) Acetylcholine receptors (muscarinic) approved 4 - 1982 small molecule antagonist 8075869 no
hexocyclium digestive system disease acm3_human primary Class A (Rhodopsin) Acetylcholine receptors (muscarinic) approved 4 - 1982 small molecule antagonist 8075869 no
histamine Anti-migraine hrh1_human primary Class A (Rhodopsin) Histamine receptors approved 4 - 1939 small molecule agonist 16648669 | 17114052 | 17222324 | 17336292 | 17478759 no
histamine for diagnosis of gastric acid secretory function hrh2_human primary Class A (Rhodopsin) Histamine receptors approved 4 - 1939 small molecule agonist 17334413 | 17359382 | 11752352 no
histrelin Antineoplastic gnrhr_human primary Class A (Rhodopsin) Gonadotrophin-releasing hormone receptors approved 4 - 1991 small molecule agonist 10969915 | 9177416 yes
homatropine methylbromide GI Anti-Ulcer ; Antimuscarinics acm5_human primary Class A (Rhodopsin) Acetylcholine receptors (muscarinic) approved 4 - 1982 small molecule antagonist 17139284 | 17016423 | 11752352 no
homatropine methylbromide GI Anti-Ulcer ; Antimuscarinics acm1_human primary Class A (Rhodopsin) Acetylcholine receptors (muscarinic) approved 4 - 1982 small molecule antagonist 17139284 | 17016423 | 20085574 | 11124384 no
homatropine methylbromide GI Anti-Ulcer ; Antimuscarinics acm2_human primary Class A (Rhodopsin) Acetylcholine receptors (muscarinic) approved 4 - 1982 small molecule antagonist 17139284 | 17016423 | 2612581 | 20085574 | 11124384 no
homatropine methylbromide GI Anti-Ulcer ; Antimuscarinics acm4_human primary Class A (Rhodopsin) Acetylcholine receptors (muscarinic) approved 4 - 1982 small molecule antagonist 17139284 | 17016423 | 6893558 no
homatropine methylbromide GI Anti-Ulcer ; Antimuscarinics acm3_human primary Class A (Rhodopsin) Acetylcholine receptors (muscarinic) approved 4 - 1982 small molecule antagonist 17139284 | 17016423 | 6893558 | 11124384 no
icatibant hereditary angioedema bkrb2_human primary Class A (Rhodopsin) Bradykinin receptors approved 4 - 2008 small molecule antagonist 14514033 | 11752352 yes
hydrocodone Analgesics oprm_human primary Class A (Rhodopsin) Opioid receptors approved 4 - 1943 small molecule agonist 11752352 | 10640321 | 16291875 | 2849950 | 14600248 | 20665209 | 18606504 no
icosapent hypertriglyceridemia ffar1_human secondary Class A (Rhodopsin) Free fatty acid receptors approved 4 - - small molecule agonist 16214394 no
indacaterol Bronchodilator adrb2_human primary Class A (Rhodopsin) Adrenoceptors approved 4 - 2009 small molecule agonist 16022567 yes
hydrocodone Analgesics oprd_human primary Class A (Rhodopsin) Opioid receptors approved 4 - 1943 small molecule agonist 16291875 | 14600248 | 11752352 no
hydromorphone Analgesics oprm_human primary Class A (Rhodopsin) Opioid receptors approved 4 - 1984 small molecule agonist 11869661 | 12479250 | 11305075 | 18789923 yes
hydromorphone Analgesics oprk_human primary Class A (Rhodopsin) Opioid receptors approved 4 - 1984 small molecule agonist 17139284 | 17016423 | 16433932 yes
hydromorphone Analgesics oprd_human primary Class A (Rhodopsin) Opioid receptors approved 4 - 1984 small molecule agonist 9301669 | 2849950 | 7511163 | 17658959 | 2478994 | 11752352 yes
hydroxyzine Antipruritics; Anxiolytics sedatives and hypnotics hrh1_human primary Class A (Rhodopsin) Histamine receptors approved 4 - 1956 small molecule antagonist 11752352 | 17222324 | 19057127 | 18781943 | 1979798 yes
hyoscyamine Antispasmodics acm2_human primary Class A (Rhodopsin) Acetylcholine receptors (muscarinic) approved 4 - - small molecule antagonist 17139284 | 17016423 | 11495349 no
iloperidone Antipsychotic ; atypical 5ht2a_human primary Class A (Rhodopsin) 5-Hydroxytryptamine receptors approved 4 - 2009 small molecule antagonist 8997630 | 12861482 no
iloperidone Antipsychotic ; atypical drd2_human primary Class A (Rhodopsin) Dopamine receptors approved 4 - 2009 small molecule antagonist 8997630 | 12861482 no
iloprost Antihypertensive pd2r2_human primary Class A (Rhodopsin) Prostanoid receptors approved 4 - 2004 small molecule agonist 9579725 yes
iloprost Antihypertensive pi2r_human primary Class A (Rhodopsin) Prostanoid receptors approved 4 - 2004 small molecule agonist 11792366 | 1375507 | 17257398 | 17273558 | 2456096 | 15163595 | 20395700 | 19683911 | 19475782 yes
iloprost Antihypertensive pe2r1_human primary Class A (Rhodopsin) Prostanoid receptors approved 4 - 2004 small molecule agonist 11999132 | 11739243 yes
ipratropium chronic obstructive pulmonary disease (COPD) acm1_human primary Class A (Rhodopsin) Acetylcholine receptors (muscarinic) approved 4 - 1986 small molecule antagonist 15987237 yes
ipratropium chronic obstructive pulmonary disease (COPD) acm2_human primary Class A (Rhodopsin) Acetylcholine receptors (muscarinic) approved 4 - 1986 small molecule antagonist 15987237 yes
ipratropium chronic obstructive pulmonary disease (COPD) acm3_human primary Class A (Rhodopsin) Acetylcholine receptors (muscarinic) approved 4 - 1986 small molecule antagonist 15987237 yes
indoramin Antihypertensive ada1a_human primary Class A (Rhodopsin) Adrenoceptors approved 4 - 1993 small molecule not available 7536677 yes
indoramin Antihypertensive ada1b_human primary Class A (Rhodopsin) Adrenoceptors approved 4 - 1993 small molecule not available 7536677 yes
indoramin Antihypertensive ada1d_human primary Class A (Rhodopsin) Adrenoceptors approved 4 - 1993 small molecule not available 7536677 yes
irbesartan Antihypertensive agtr1_human primary Class A (Rhodopsin) Angiotensin receptors approved 4 - 1997 small molecule antagonist 11752352 | 17408613 | 15030294 | 11486244 | 14716205 | 7843749 | 10069682 | 10075381 | 10082498 | 10373224 | 10822210 | 18627212 | 15101793 yes
isoetharine Anti-Asthmatic adrb1_human primary Class A (Rhodopsin) Adrenoceptors approved 4 - 1979 small molecule antagonist 6125600 no
isoetharine Bronchodilator adrb1_human primary Class A (Rhodopsin) Adrenoceptors approved 4 - 1979 small molecule agonist 6125600 no
isometheptene migraines ada1a_human primary Class A (Rhodopsin) Adrenoceptors approved 4 - - small molecule agonist 15094323 | 3129549 yes
isometheptene Anti-migraine ada1a_human primary Class A (Rhodopsin) Adrenoceptors approved 4 - 1962 small molecule agonist 15094323 | 3129549 yes
isopropamide digestive system disease acm1_human primary Class A (Rhodopsin) Acetylcholine receptors (muscarinic) approved 4 - 1957 small molecule antagonist 3580704 | 29133 no
isopropamide digestive system disease acm3_human primary Class A (Rhodopsin) Acetylcholine receptors (muscarinic) approved 4 - 1957 small molecule antagonist 3580704 | 29133 no
isoproterenol cardiovascular ; Anti-Asthmatic adrb2_human primary Class A (Rhodopsin) Adrenoceptors approved 4 - 1956 small molecule agonist 10988267 no
isoproterenol Bronchodilator ; Cardiotonic adrb2_human primary Class A (Rhodopsin) Adrenoceptors approved 4 - 1956 small molecule agonist 10988267 no
isoproterenol cardiovascular ; Anti-Asthmatic adrb1_human primary Class A (Rhodopsin) Adrenoceptors approved 4 - 1956 small molecule agonist 11791000 no
isoproterenol Bronchodilator ; Cardiotonic adrb1_human primary Class A (Rhodopsin) Adrenoceptors approved 4 - 1956 small molecule agonist 11791000 no
isothipendyl antipruritic hrh1_human primary Class A (Rhodopsin) Histamine receptors approved 4 - - small molecule antagonist 8546983 no
itraconazole Antineoplastic smo_human primary Class F (Frizzled) Frizzled approved 4 - 1992 small molecule antagonist 20385363 yes
ketobemidone Analgesics oprd_human primary Class A (Rhodopsin) Opioid receptors approved 4 - - small molecule agonist 8153059 no
ketobemidone Analgesics oprk_human primary Class A (Rhodopsin) Opioid receptors approved 4 - - small molecule agonist 8153059 no
ketobemidone Analgesics oprm_human primary Class A (Rhodopsin) Opioid receptors approved 4 - - small molecule agonist 8878254 | 8153059 no
ketotifen Anti-Allergic hrh1_human primary Class A (Rhodopsin) Histamine receptors approved 4 - 1999 small molecule antagonist 7893266 | 1434122 | 16404130 | 8836617 | 8101246 | 18490184 | 11752352 yes
levallorphan Opiate Antagonists oprm_human primary Class A (Rhodopsin) Opioid receptors approved 4 - 1982 small molecule antagonist 8968334 | 7723747 | 9016350 | 8819494 | 9862398 no
labetalol cardiovascular disease ada2a_human primary Class A (Rhodopsin) Adrenoceptors approved 4 - 1984 small molecule antagonist 6355664 yes
labetalol cardiovascular disease ada2b_human primary Class A (Rhodopsin) Adrenoceptors approved 4 - 1984 small molecule antagonist 6355664 yes
labetalol cardiovascular disease ada2c_human primary Class A (Rhodopsin) Adrenoceptors approved 4 - 1984 small molecule antagonist 6355664 yes
labetalol Antihypertensive adrb2_human primary Class A (Rhodopsin) Adrenoceptors approved 4 - 1984 small molecule antagonist 1361547 | 2907566 | 11752352 | 6355664 | 19879818 | 8104240 | 7684671 yes
labetalol Antihypertensive adrb1_human primary Class A (Rhodopsin) Adrenoceptors approved 4 - 1984 small molecule antagonist 1687367 | 6151824 | 6355664 | 7286847 | 11752352 | 19879818 | 8104240 | 7684671 yes
levobunolol Antiglaucomic adrb2_human primary Class A (Rhodopsin) Adrenoceptors approved 4 - 1985 small molecule antagonist 11752352 | 6147147 | 11572462 | 7928182 | 1351412 | 2892662 | 2891463 yes
labetalol cardiovascular disease ada1d_human primary Class A (Rhodopsin) Adrenoceptors approved 4 - 1984 small molecule antagonist 2696507 | 10529655 yes
labetalol cardiovascular disease adrb3_human primary Class A (Rhodopsin) Adrenoceptors approved 4 - 1984 small molecule antagonist 2696507 | 10529655 yes
labetalol Antihypertensive ada1a_human primary Class A (Rhodopsin) Adrenoceptors approved 4 - 1984 small molecule antagonist 2696507 | 10529655 yes
labetalol Antihypertensive ada1b_human primary Class A (Rhodopsin) Adrenoceptors approved 4 - 1984 small molecule antagonist 2696507 | 10529655 yes
lanreotide acromegaly ssr1_human primary Class A (Rhodopsin) Somatostatin receptors approved 4 - 2007 peptide agonist 15103227 yes
lanreotide acromegaly ssr5_human primary Class A (Rhodopsin) Somatostatin receptors approved 4 - 2007 peptide agonist 26416534 yes
lanreotide Antineoplastic ssr2_human primary Class A (Rhodopsin) Somatostatin receptors approved 4 - 2007 peptide agonist 26416534 yes
levobunolol Antiglaucomic adrb1_human primary Class A (Rhodopsin) Adrenoceptors approved 4 - 1985 small molecule antagonist 2891463 | 7928182 | 10864881 | 11572462 | 1351412 | 2892662 yes
levocabastine Anti-Allergic ntr2_human primary Class A (Rhodopsin) Neurotensin receptors approved 4 - 1993 small molecule antagonist 11723247 | 8647296 | 9080465 yes
latanoprost Antiglaucomic pf2r_human primary Class A (Rhodopsin) Prostanoid receptors approved 4 - 1996 small molecule agonist 16249494 | 14646172 | 15037111 | 9733584 | 12204699 | 11752352 yes
leuprolide Antineoplastic gnrhr_human primary Class A (Rhodopsin) Gonadotrophin-releasing hormone receptors approved 4 - 1985 peptide agonist 16809153 | 10687850 | 9625809 | 15758569 | 10394541 no
levocabastine Anti-Allergic hrh1_human primary Class A (Rhodopsin) Histamine receptors approved 4 - 1993 small molecule antagonist 11752352 | 10631382 | 8647296 | 9627096 | 9551716 | 11915520 yes
leuprolide Antineoplastic ; endometriosis gnrhr_human primary Class A (Rhodopsin) Gonadotrophin-releasing hormone receptors approved 4 - 1985 peptide agonist 16809153 | 10687850 | 9625809 | 15758569 | 10394541 no
leuprolide Alzheimer's disease gnrhr_human primary Class A (Rhodopsin) Gonadotrophin-releasing hormone receptors approved 4 - 1985 peptide agonist 16809153 | 10687850 | 9625809 | 15758569 | 10394541 no
levocetirizine Anti-Allergic hrh1_human primary Class A (Rhodopsin) Histamine receptors approved 4 - 2007 small molecule antagonist 21639816 | 18336052 yes
levodopa Antiparkinson drd2_human primary Class A (Rhodopsin) Dopamine receptors approved 4 - 1993 small molecule agonist 17553470 | 15710490 | 15824260 | 15728856 | 18549347 | 11978145 | 9633680 yes
levodopa Antiparkinson drd2_human primary Class A (Rhodopsin) Dopamine receptors approved 4 - 2015 small molecule agonist 17553470 | 15710490 | 15824260 | 15728856 | 18549347 | 11978145 | 9633680 yes
levodopa Antiparkinson drd1_human primary Class A (Rhodopsin) Dopamine receptors approved 4 - 2015 small molecule agonist 18549347 | 11978145 | 9633680 yes
levodopa Antiparkinson drd3_human primary Class A (Rhodopsin) Dopamine receptors approved 4 - 2015 small molecule agonist 18549347 | 11978145 | 9633680 yes
levodopa Antiparkinson drd4_human primary Class A (Rhodopsin) Dopamine receptors approved 4 - 2015 small molecule agonist 18549347 | 11978145 | 9633680 yes
levodopa Antiparkinson drd5_human primary Class A (Rhodopsin) Dopamine receptors approved 4 - 2015 small molecule agonist 18549347 | 11978145 | 9633680 yes
levorphanol Analgesics oprm_human primary Class A (Rhodopsin) Opioid receptors approved 4 - 1953 small molecule agonist 12975489 | 17039381 no
levodopa Antiparkinson drd1_human primary Class A (Rhodopsin) Dopamine receptors approved 4 - 1993 small molecule agonist 18549347 | 11978145 | 9633680 yes
levodopa Antiparkinson drd3_human primary Class A (Rhodopsin) Dopamine receptors approved 4 - 1993 small molecule agonist 18549347 | 11978145 | 9633680 yes
levodopa Antiparkinson drd4_human primary Class A (Rhodopsin) Dopamine receptors approved 4 - 1993 small molecule agonist 18549347 | 11978145 | 9633680 yes
levodopa Antiparkinson drd5_human primary Class A (Rhodopsin) Dopamine receptors approved 4 - 1993 small molecule agonist 18549347 | 11978145 | 9633680 yes
levomepromazine psychosis drd2_human primary Class A (Rhodopsin) Dopamine receptors approved 4 - 1982 small molecule antagonist 2870716 yes
levomepromazine psychosis drd4_human primary Class A (Rhodopsin) Dopamine receptors approved 4 - 1982 small molecule antagonist 2870716 yes
levomepromazine psychosis drd3_human primary Class A (Rhodopsin) Dopamine receptors approved 4 - 1982 small molecule antagonist 10741754 yes
levomepromazine schizophrenia drd3_human primary Class A (Rhodopsin) Dopamine receptors approved 4 - 1982 small molecule antagonist 10741754 yes
levomepromazine schizophrenia 5ht2b_human primary Class A (Rhodopsin) 5-Hydroxytryptamine receptors approved 4 - 1982 small molecule antagonist 15701205 yes
levomethadyl acetate Analgesics oprm_human primary Class A (Rhodopsin) Opioid receptors approved 4 - 1993 small molecule agonist 9360954 | 2471291 | 10911931 | 11561100 | 11752352 no
levonordefrin decongestant ada1a_human primary Class A (Rhodopsin) Adrenoceptors approved 4 - 1960 small molecule agonist 19326476 no
levonordefrin nasal decongestant ada1a_human primary Class A (Rhodopsin) Adrenoceptors approved 4 - 1960 small molecule agonist 19326476 no
levosalbutamol Anti-Asthmatic adrb2_human primary Class A (Rhodopsin) Adrenoceptors approved 4 - 1999 small molecule agonist 21453221 no
liraglutide Antidiabetic glp1r_human primary Class B1 (Secretin) Glucagon receptor family approved 4 - 2009 protein agonist 14678021 | 18333889 yes
liraglutide Antidiabetic glp1r_human primary Class B1 (Secretin) Glucagon receptor family approved 4 - 2010 protein agonist 14678021 | 18333889 yes
lisdexamfetamine Central Nervous System Stimulants ada1b_human primary Class A (Rhodopsin) Adrenoceptors approved 4 - 2007 small molecule antagonist 17016423 | 11752352 yes
lisdexamfetamine Central Nervous System Stimulants taar1_human primary Class A (Rhodopsin) Trace amine receptors approved 4 - 2007 small molecule antagonist 17016423 | 11752352 yes
lisuride Antiparkinson 5ht1a_human primary Class A (Rhodopsin) 5-Hydroxytryptamine receptors approved 4 - 2011 small molecule agonist 11224054 | 18691132 | 12373423 | 1678728 | 1783326 | 2887435 no
lisuride Antiparkinson drd2_human primary Class A (Rhodopsin) Dopamine receptors approved 4 - 2011 small molecule agonist 11752352 | 18691132 no
lisuride Antiparkinson drd1_human primary Class A (Rhodopsin) Dopamine receptors approved 4 - 2011 small molecule agonist 17139284 | 17016423 | 18691132 no
lixisenatide Antidiabetic glp1r_human primary Class B1 (Secretin) Glucagon receptor family approved 4 - 2016 small molecule agonist 25119443 yes
lofexidine opiate withdrawal ada2b_human primary Class A (Rhodopsin) Adrenoceptors approved 4 - 2006 small molecule agonist 1357064 | 10598217 yes
lofexidine opiate withdrawal ada2c_human primary Class A (Rhodopsin) Adrenoceptors approved 4 - 2006 small molecule agonist 1357064 | 10598217 yes
lofexidine opiate withdrawal ada2a_human primary Class A (Rhodopsin) Adrenoceptors approved 4 - 2006 small molecule agonist 1357064 | 10598217 | 10882840 yes
loperamide Antidiuretic oprm_human primary Class A (Rhodopsin) Opioid receptors approved 4 - 1976 small molecule agonist 10087042 | 14592702 | 8488368 | 11752352 | 6319884 | 18284554 yes
loratadine Anti-Asthmatic hrh1_human primary Class A (Rhodopsin) Histamine receptors approved 4 - 1993 small molecule antagonist 11752352 | 1303772 | 7581058 | 8174605 | 10597865 | 15942272 | 1303773 | 9444440 | 1977506 | 11291777 yes
lorcaserin Anti-obesity 5ht2c_human primary Class A (Rhodopsin) 5-Hydroxytryptamine receptors approved 4 - 2012 small molecule agonist 16625817 | 16259227 no
losartan Antihypertensive ; for Diabetic neuropathy agtr1_human primary Class A (Rhodopsin) Angiotensin receptors approved 4 - 1995 small molecule antagonist 11752352 | 15026875 | 15991937 | 12710529 | 12719755 | 15573751 yes
losartan Antihypertensive agtr1_human primary Class A (Rhodopsin) Angiotensin receptors approved 4 - 1995 small molecule antagonist 11752352 | 15026875 | 15991937 | 12710529 | 12719755 | 15573751 yes
loxapine schizophrenia 5ht2a_human primary Class A (Rhodopsin) 5-Hydroxytryptamine receptors approved 4 - 1975 small molecule antagonist 12664192 yes
loxapine schizophrenia drd2_human primary Class A (Rhodopsin) Dopamine receptors approved 4 - 1975 small molecule antagonist 6239298 | 15694653 | 9570468 | 8101879 | 9342550 | 8665533 | 11752352 yes
mepenzolate digestive system disease acm1_human primary Class A (Rhodopsin) Acetylcholine receptors (muscarinic) approved 4 - 1956 small molecule antagonist 7623487 | 2791613 | 7122991 yes
mepenzolate digestive system disease acm3_human primary Class A (Rhodopsin) Acetylcholine receptors (muscarinic) approved 4 - 1956 small molecule antagonist 7623487 | 2791613 | 7122991 yes
meperidine, pethidine Analgesics oprk_human primary Class A (Rhodopsin) Opioid receptors approved 4 - 1942 small molecule agonist 28625303 | 26732307 no
lurasidone schizophrenia 5ht2a_human primary Class A (Rhodopsin) 5-Hydroxytryptamine receptors approved 4 - 2010 small molecule antagonist 23545936 yes
lurasidone schizophrenia drd2_human primary Class A (Rhodopsin) Dopamine receptors approved 4 - 2010 small molecule antagonist 23545936 yes
lutropin alfa Fertility lshr_human primary Class A (Rhodopsin) Glycoprotein hormone receptors approved 4 - 2004 peptide agonist 17139284 | 17016423 | 20161981 | 11752352 yes
macitentan cardiovascular disease ednra_human primary Class A (Rhodopsin) Endothelin receptors approved 4 - 2013 small molecule antagonist 22862294 | 22458347 | 24261583 yes
macitentan cardiovascular disease ednrb_human primary Class A (Rhodopsin) Endothelin receptors approved 4 - 2013 small molecule antagonist 22862294 | 22458347 | 24261583 yes
maraviroc antiviral ; HIV ccr5_human primary Class A (Rhodopsin) Chemokine receptors approved 4 - 2007 small molecule antagonist 17139284 | 17016423 | 11752352 | 19098484 | 19692476 | 16298345 yes
marinol Antiemetics cnr1_human primary Class A (Rhodopsin) Cannabinoid receptors approved 4 - 1985 small molecule agonist 17828291 no
meclizine Antiemetics hrh1_human primary Class A (Rhodopsin) Histamine receptors approved 4 - 1957 small molecule antagonist 7513381 | 1350745 | 1362160 | 1678430 no
melatonin Hypnotics and Sedatives mtr1a_human primary Class A (Rhodopsin) Melatonin approved 4 - 2005 small molecule agonist 19463840 | 11752352 | 15992934 | 19449447 | 20827520 | 20674373 | 19966183 yes
melatonin Hypnotics and Sedatives mtr1b_human primary Class A (Rhodopsin) Melatonin approved 4 - 2005 small molecule agonist 19463840 | 15992934 | 19449447 | 20827520 | 20674373 | 19966183 yes
methacholine Anti-Asthmatic acm3_human primary Class A (Rhodopsin) Acetylcholine receptors (muscarinic) approved 4 - 1986 small molecule agonist 20888332 | 20347047 | 19951374 | 19460789 no
methadone Analgesics oprm_human primary Class A (Rhodopsin) Opioid receptors approved 4 - 1947 small molecule agonist 17139284 | 17016423 | 11933204 | 17850768 | 14991152 yes
melevodopa Antiparkinson drd1_human primary Class A (Rhodopsin) Dopamine receptors approved 4 - 2000 small molecule agonist 20302892 no
melevodopa Antiparkinson drd2_human primary Class A (Rhodopsin) Dopamine receptors approved 4 - 2000 small molecule agonist 20302892 no
melevodopa Antiparkinson drd3_human primary Class A (Rhodopsin) Dopamine receptors approved 4 - 2000 small molecule agonist 20302892 no
melevodopa Antiparkinson drd4_human primary Class A (Rhodopsin) Dopamine receptors approved 4 - 2000 small molecule agonist 20302892 no
melevodopa Antiparkinson drd5_human primary Class A (Rhodopsin) Dopamine receptors approved 4 - 2000 small molecule agonist 20302892 no
menotropins, menotrophin Fertility lshr_human primary Class A (Rhodopsin) Glycoprotein hormone receptors approved 4 - 1975 protein agonist 17139284 | 17016423 | 14680547 | 7872378 no
menotropins, menotrophin Fertility fshr_human primary Class A (Rhodopsin) Glycoprotein hormone receptors approved 4 - 1975 protein agonist 17139284 | 17016423 | 14680547 | 7872378 | 11752352 no
methadyl acetate Analgesics oprm_human primary Class A (Rhodopsin) Opioid receptors approved 4 - 1993 small molecule agonist 20163389 | 6268422 | 19153939 | 11752352 no
methamphetamine neuroprotectant taar1_human secondary Class A (Rhodopsin) Trace amine receptors approved 4 - 1943 small molecule agonist 17888514 | 11459929 | 17218486 | 17234900 | 17212650 | 17234899 | 15764732 no
mephentermine cardiovascular disease ada1b_human primary Class A (Rhodopsin) Adrenoceptors approved 4 - 1951 small molecule agonist 21182601 | 5334234 no
mephentermine cardiovascular disease ada1d_human primary Class A (Rhodopsin) Adrenoceptors approved 4 - 1951 small molecule agonist 21182601 | 5334234 no
mephentermine cardiovascular disease ada2a_human primary Class A (Rhodopsin) Adrenoceptors approved 4 - 1951 small molecule agonist 21182601 | 5334234 no
mephentermine cardiovascular disease ada2b_human primary Class A (Rhodopsin) Adrenoceptors approved 4 - 1951 small molecule agonist 21182601 | 5334234 no
mephentermine cardiovascular disease ada2c_human primary Class A (Rhodopsin) Adrenoceptors approved 4 - 1951 small molecule agonist 21182601 | 5334234 no
mephentermine cardiovascular disease adrb1_human primary Class A (Rhodopsin) Adrenoceptors approved 4 - 1951 small molecule agonist 21182601 | 5334234 no
mephentermine cardiovascular disease adrb2_human primary Class A (Rhodopsin) Adrenoceptors approved 4 - 1951 small molecule agonist 21182601 | 5334234 no
mephentermine cardiovascular disease adrb3_human primary Class A (Rhodopsin) Adrenoceptors approved 4 - 1951 small molecule agonist 21182601 | 5334234 no
mephentermine Antihypotensive ; Vasoconstrictor ada1a_human primary Class A (Rhodopsin) Adrenoceptors approved 4 - 1951 small molecule agonist 21182601 | 5334234 no
mequitazine Anti-Allergic hrh1_human primary Class A (Rhodopsin) Histamine receptors approved 4 - - small molecule antagonist 9454781 | 7650688 | 8808167 | 7511558 | 12244568 | 6418550 | 11752352 no
mesoridazine schizophrenia drd2_human primary Class A (Rhodopsin) Dopamine receptors approved 4 - 1970 small molecule antagonist 11752352 | 16135699 | 15357957 no
mesoridazine schizophrenia 5ht2a_human primary Class A (Rhodopsin) 5-Hydroxytryptamine receptors approved 4 - 1970 small molecule antagonist 15357957 | 11561066 | 10991983 no
metaproterenol, orciprenaline Anti-Asthmatic adrb2_human primary Class A (Rhodopsin) Adrenoceptors approved 4 - 1973 small molecule agonist 10490901 | 3168573 | 2870555 | 8760245 | 10973730 | 11752352 no
metaraminol Antihypotensive ; Vasoconstrictor ada1a_human primary Class A (Rhodopsin) Adrenoceptors approved 4 - 1954 small molecule agonist 17139284 | 17016423 | 9663612 no
methantheline GI Anti-Ulcer ; anticholinergic; Antispasmodics acm1_human primary Class A (Rhodopsin) Acetylcholine receptors (muscarinic) approved 4 - 1951 small molecule antagonist 17139284 | 17016423 no
methamphetamine neuroprotectant ada2b_human secondary Class A (Rhodopsin) Adrenoceptors approved 4 - 1943 small molecule agonist 9551769 | 15955613 no
methamphetamine neuroprotectant ada2c_human secondary Class A (Rhodopsin) Adrenoceptors approved 4 - 1943 small molecule agonist 9551769 | 15955613 no
methamphetamine neuroprotectant ada2a_human secondary Class A (Rhodopsin) Adrenoceptors approved 4 - 1943 small molecule agonist 9551769 | 15955613 | 12453616 no
methantheline digestive system disease hrh2_human primary Class A (Rhodopsin) Histamine receptors approved 4 - 1951 small molecule antagonist 6116801 no
methdilazine Anti-Allergic hrh1_human primary Class A (Rhodopsin) Histamine receptors approved 4 - 1982 small molecule antagonist 17139284 | 17016423 | 11752352 | 9700532 | 20012879 no
methoxamine cardiovascular disease ada1d_human primary Class A (Rhodopsin) Adrenoceptors approved 4 - 1982 small molecule agonist 19493707 no
methoxamine Antihypotensive ; Vasoconstrictor ada1b_human primary Class A (Rhodopsin) Adrenoceptors approved 4 - 1982 small molecule agonist 2546049 | 2988814 | 8635240 | 11752352 | 11331292 no
methoxamine Antihypotensive ; Vasoconstrictor ada1a_human primary Class A (Rhodopsin) Adrenoceptors approved 4 - 1982 small molecule agonist 7875228 | 1978244 | 1680715 | 7511752 | 8986981 no
methyldopa Antihypertensive ada2a_human primary Class A (Rhodopsin) Adrenoceptors approved 4 - 1962 small molecule agonist 17139284 | 17016423 | 17485976 | 9284427 | 10415926 | 8743022 | 1363322 | 14557373 yes
methylergonovine Abortifacient drd1_human primary Class A (Rhodopsin) Dopamine receptors approved 4 - 1946 small molecule partial agonist 15930499 no
methylnaltrexone opioid-induced constipation oprm_human primary Class A (Rhodopsin) Opioid receptors approved 4 - 2008 small molecule antagonist 17504835 yes
methylnaltrexone OIC treatment oprm_human primary Class A (Rhodopsin) Opioid receptors approved 4 - 2008 small molecule antagonist 17504835 yes
methylscopolamine, methscopolamine Anti-ulcer acm1_human primary Class A (Rhodopsin) Acetylcholine receptors (muscarinic) approved 4 - 1953 small molecule antagonist 17139284 | 17016423 | 20590642 no
methylscopolamine, methscopolamine Antispasmodics acm1_human primary Class A (Rhodopsin) Acetylcholine receptors (muscarinic) approved 4 - 1953 small molecule antagonist 17139284 | 17016423 | 20590642 no
methylscopolamine Anti-ulcer acm2_human primary Class A (Rhodopsin) Acetylcholine receptors (muscarinic) approved 4 - 1953 small molecule antagonist 19565307 | 11752352 no
methysergide Anti-migraine 5ht2b_human primary Class A (Rhodopsin) 5-Hydroxytryptamine receptors approved 4 - 1962 small molecule antagonist 8743744 yes
methysergide Anti-migraine s; Vasoconstrictor 5ht7r_human primary Class A (Rhodopsin) 5-Hydroxytryptamine receptors approved 4 - 1962 small molecule antagonist 14501155 yes
methysergide Anti-migraine s; Vasoconstrictor 5ht2a_human primary Class A (Rhodopsin) 5-Hydroxytryptamine receptors approved 4 - 1962 small molecule antagonist 10080233 | 10455282 | 11061982 | 11704657 | 11720080 yes
methysergide Anti-migraine s; Vasoconstrictor 5ht1a_human primary Class A (Rhodopsin) 5-Hydroxytryptamine receptors approved 4 - 1962 small molecule antagonist 11049861 | 14501155 | 14517765 | 14581123 | 1838579 yes
methysergide Anti-migraine s; Vasoconstrictor 5ht2c_human primary Class A (Rhodopsin) 5-Hydroxytryptamine receptors approved 4 - 1962 small molecule antagonist 11752352 | 12555241 yes
metiamide acid reducer hrh2_human primary Class A (Rhodopsin) Histamine receptors approved 4 - - small molecule antagonist 7725982 no
metipranolol Anti-Arrhythmia ; Antihypertensive ; Anti-glaucoma adrb1_human primary Class A (Rhodopsin) Adrenoceptors approved 4 - 1989 small molecule antagonist 17139284 | 17016423 | 2895037 | 12967722 | 2885244 yes
metipranolol Anti-Arrhythmia ; Antihypertensive ; Anti-glaucoma adrb2_human primary Class A (Rhodopsin) Adrenoceptors approved 4 - 1989 small molecule antagonist 17139284 | 17016423 | 2895037 | 2876128 | 12967722 | 2885244 yes
metixene, methixene Antiparkinson acm1_human primary Class A (Rhodopsin) Acetylcholine receptors (muscarinic) approved 4 - 1982 small molecule antagonist 17139284 | 17016423 no
mianserin Anti-depressant 5ht2a_human primary Class A (Rhodopsin) 5-Hydroxytryptamine receptors approved 4 - 1996 small molecule antagonist 11004734 yes
mianserin Anti-depressant 5ht2c_human primary Class A (Rhodopsin) 5-Hydroxytryptamine receptors approved 4 - 1996 small molecule antagonist 11004734 yes
metixene Antiparkinson acm2_human primary Class A (Rhodopsin) Acetylcholine receptors (muscarinic) approved 4 - 1982 small molecule antagonist 17139284 | 17016423 no
metixene Antiparkinson acm3_human primary Class A (Rhodopsin) Acetylcholine receptors (muscarinic) approved 4 - 1982 small molecule antagonist 17139284 | 17016423 no
metixene Antiparkinson acm4_human primary Class A (Rhodopsin) Acetylcholine receptors (muscarinic) approved 4 - 1982 small molecule antagonist 17139284 | 17016423 no
metixene Antiparkinson acm5_human primary Class A (Rhodopsin) Acetylcholine receptors (muscarinic) approved 4 - 1982 small molecule antagonist 17139284 | 17016423 | 11752352 no
metoclopramide motilitant; gastroesophageal reflux disease drd2_human primary Class A (Rhodopsin) Dopamine receptors approved 4 - 1979 small molecule antagonist 11752352 | 8730709 | 8230103 | 7745844 | 8981558 | 9876882 | 15835479 yes
metoclopramide Antiemetics drd2_human primary Class A (Rhodopsin) Dopamine receptors approved 4 - 1979 small molecule antagonist 11752352 | 8730709 | 8230103 | 7745844 | 8981558 | 9876882 | 15835479 yes
metoclopramide motilitant; gastroesophageal reflux disease acm1_human primary Class A (Rhodopsin) Acetylcholine receptors (muscarinic) approved 4 - 1979 small molecule agonist 17139284 | 17016423 | 16466463 | 15835479 yes
metoclopramide Antiemetics acm1_human primary Class A (Rhodopsin) Acetylcholine receptors (muscarinic) approved 4 - 1979 small molecule agonist 17139284 | 17016423 | 16466463 | 15835479 yes
metoprolol Antihypertensive adrb1_human primary Class A (Rhodopsin) Adrenoceptors approved 4 - 1978 small molecule antagonist 10913016 | 11448474 | 12679135 | 12844134 | 14534524 | 11752352 yes
metoprolol Anti-Arrhythmia ; Antihypertensive adrb1_human primary Class A (Rhodopsin) Adrenoceptors approved 4 - 1978 small molecule antagonist 10913016 | 11448474 | 12679135 | 12844134 | 14534524 | 11752352 yes
mianserin Anti-depressant ada2a_human primary Class A (Rhodopsin) Adrenoceptors approved 4 - 1996 small molecule antagonist 16814817 yes
mianserin Anti-depressant hrh1_human primary Class A (Rhodopsin) Histamine receptors approved 4 - 1996 small molecule antagonist 12967590 | 11004734 | 6302549 yes
midodrine cardiovascular disease ada1d_human primary Class A (Rhodopsin) Adrenoceptors approved 4 - 1996 small molecule agonist 12238918 yes
midodrine Antihypotensive ; Vasoconstrictor ada1b_human primary Class A (Rhodopsin) Adrenoceptors approved 4 - 1996 small molecule agonist 15163201 yes
midodrine Antihypotensive ; Vasoconstrictor ada1a_human primary Class A (Rhodopsin) Adrenoceptors approved 4 - 1996 small molecule agonist 12163120 | 9007522 | 15163201 yes
minaprine Anti-depressant 5ht2a_human primary Class A (Rhodopsin) 5-Hydroxytryptamine receptors approved 4 withdrawn 1984 small molecule antagonist 1361012 | 2530096 | 2975224 | 3836113 no
minaprine Anti-depressant 5ht2c_human primary Class A (Rhodopsin) 5-Hydroxytryptamine receptors approved 4 withdrawn 1984 small molecule antagonist 17139284 | 17016423 | 1361012 | 2975224 no
minaprine Anti-depressant 5ht2b_human primary Class A (Rhodopsin) 5-Hydroxytryptamine receptors approved 4 withdrawn 1984 small molecule antagonist 17139284 | 17016423 | 1361012 | 2975224 | 11752352 no
mirabegron incontinence adrb3_human primary Class A (Rhodopsin) Adrenoceptors approved 4 - 2012 small molecule agonist 23550899 yes
mirtazapine Anti-depressant 5ht2a_human primary Class A (Rhodopsin) 5-Hydroxytryptamine receptors approved 4 - 1996 small molecule antagonist 10446734 | 10446735 | 10446738 | 10451911 | 11063897 | 11607047 yes
mirtazapine unipolar depression 5ht2c_human primary Class A (Rhodopsin) 5-Hydroxytryptamine receptors approved 4 - 1996 small molecule antagonist 14615872 | 10762339 | 9832994 | 16433010 | 11271412 | 11752352 yes
mirtazapine Anti-depressant ada2a_human primary Class A (Rhodopsin) Adrenoceptors approved 4 - 1996 small molecule antagonist 14628003 | 11607047 | 10793320 | 11931344 | 11939713 | 12523492 yes
misoprostol hemorrhage pe2r2_human primary Class A (Rhodopsin) Prostanoid receptors approved 4 - 1988 small molecule agonist 16039053 | 18472336 | 12097143 | 9313928 | 11602631 yes
misoprostol hemorrhage pe2r3_human primary Class A (Rhodopsin) Prostanoid receptors approved 4 - 1988 small molecule agonist 16039053 | 18472336 | 12097143 | 9313928 | 11602631 yes
mivacurium Muscle Relaxants acm2_human primary Class A (Rhodopsin) Acetylcholine receptors (muscarinic) approved 4 - 1992 small molecule antagonist 17139284 | 17016423 yes
molindone schizophrenia drd2_human primary Class A (Rhodopsin) Dopamine receptors approved 4 - 1974 small molecule antagonist 17016423 | 9577836 | 9353417 | 9342550 | 11752352 no
montelukast Anti-Asthmatic cltr1_human primary Class A (Rhodopsin) Leukotriene receptors approved 4 - 1998 small molecule antagonist 15013935 | 15456537 | 16815057 | 16815146 | 17199874 | 11752352 yes
morphine Analgesics oprd_human primary Class A (Rhodopsin) Opioid receptors approved 4 - 1984 small molecule agonist 16530171 | 16534251 | 16539674 | 16650582 | 16678156 | 11752352 | 12015197 yes
morphine Analgesics oprd_human primary Class A (Rhodopsin) Opioid receptors approved 4 - 2002 small molecule agonist 16530171 | 16534251 | 16539674 | 16650582 | 16678156 | 11752352 | 12015197 yes
morphine Analgesics; opioid addiction oprd_human primary Class A (Rhodopsin) Opioid receptors approved 4 - 1984 small molecule agonist 16530171 | 16534251 | 16539674 | 16650582 | 16678156 | 11752352 | 12015197 yes
morphine Analgesics oprm_human primary Class A (Rhodopsin) Opioid receptors approved 4 - 1984 small molecule agonist 16530171 | 16580639 | 16580848 | 16682505 | 11752352 yes
morphine Analgesics oprm_human primary Class A (Rhodopsin) Opioid receptors approved 4 - 2002 small molecule agonist 16530171 | 16580639 | 16580848 | 16682505 | 11752352 yes
morphine Analgesics; opioid addiction oprm_human primary Class A (Rhodopsin) Opioid receptors approved 4 - 1984 small molecule agonist 16530171 | 16580639 | 16580848 | 16682505 | 11752352 yes
morphine Analgesics oprk_human primary Class A (Rhodopsin) Opioid receptors approved 4 - 1984 small molecule agonist 17139284 | 17016423 | 9808678 | 7959748 | 16753266 yes
morphine Analgesics oprk_human primary Class A (Rhodopsin) Opioid receptors approved 4 - 2002 small molecule agonist 17139284 | 17016423 | 9808678 | 7959748 | 16753266 yes
morphine Analgesics; opioid addiction oprk_human primary Class A (Rhodopsin) Opioid receptors approved 4 - 1984 small molecule agonist 17139284 | 17016423 | 9808678 | 7959748 | 16753266 yes
nabilone Antiemetics cnr2_human primary Class A (Rhodopsin) Cannabinoid receptors approved 4 - 1985 small molecule agonist 11786493 | 17450170 | 17139494 | 15221424 | 11698062 yes
nabilone Antiemetics cnr1_human primary Class A (Rhodopsin) Cannabinoid receptors approved 4 - 1985 small molecule agonist 17139494 | 11698062 | 8981483 | 10575283 | 8864542 | 11752352 yes
nadolol Anti-Arrhythmia ; Antihypertensive adrb1_human primary Class A (Rhodopsin) Adrenoceptors approved 4 - 1979 small molecule antagonist 11752352 | 7981009 | 1354084 | 10433496 | 10606440 | 7912539 yes
nadolol Anti-Arrhythmia ; Antihypertensive adrb2_human primary Class A (Rhodopsin) Adrenoceptors approved 4 - 1979 small molecule antagonist 11752352 | 7981009 | 17622774 | 8574280 | 1349493 | 10433496 yes
nafarelin Antiendometriosis gnrhr_human primary Class A (Rhodopsin) Gonadotrophin-releasing hormone receptors approved 4 - 1990 small molecule agonist 2137975 | 14687742 | 14644830 | 17097577 | 9622415 | 7996307 | 1830521 | 2140979 | 2151003 | 11752352 yes
nalbuphine Analgesics oprm_human primary Class A (Rhodopsin) Opioid receptors approved 4 - 1979 small molecule agonist 10844102 | 8388112 | 9084061 | 9399970 | 18425947 | 16517095 | 19403853 | 15602503 | 18810678 | 17407276 yes
nalbuphine Analgesics oprk_human primary Class A (Rhodopsin) Opioid receptors approved 4 - 1979 small molecule agonist 17139284 | 17016423 | 8388112 | 15655510 | 16517095 | 19403853 | 15602503 | 10534607 | 17407276 yes
nalbuphine Analgesics oprd_human primary Class A (Rhodopsin) Opioid receptors approved 4 - 1979 small molecule agonist 8093631 | 2826773 | 11752352 yes
naldemedine opioid-induced constipation oprm_human primary Class A (Rhodopsin) Opioid receptors approved 4 - 2017 small molecule antagonist 25442002 no
nalmefene smoking-cessation ; addiction oprm_human primary Class A (Rhodopsin) Opioid receptors approved 4 - 2013 small molecule antagonist 25442002 yes
nalmefene pruritus oprm_human primary Class A (Rhodopsin) Opioid receptors approved 4 - 1995 small molecule antagonist 25442002 yes
nalmefene smoking-cessation ; addiction oprd_human primary Class A (Rhodopsin) Opioid receptors approved 4 - 2013 small molecule antagonist 28844812 | 28721822 yes
nalmefene smoking-cessation ; addiction oprk_human primary Class A (Rhodopsin) Opioid receptors approved 4 - 2013 small molecule antagonist 28844812 | 28721823 yes
nalmefene pruritus oprd_human primary Class A (Rhodopsin) Opioid receptors approved 4 - 1995 small molecule antagonist 28844812 | 28721824 yes
nalmefene pruritus oprk_human primary Class A (Rhodopsin) Opioid receptors approved 4 - 1995 small molecule antagonist 28844812 | 28721825 yes
naloxegol opioid-induced constipation oprm_human primary Class A (Rhodopsin) Opioid receptors approved 4 - 2014 small molecule antagonist 25471070 yes
naloxone Analgesics; opioid addiction oprm_human primary Class A (Rhodopsin) Opioid receptors approved 4 - 1971 small molecule antagonist 12566163 | 12799988 | 12842269 | 12887410 | 12909198 | 11752352 | 18354714 | 17918759 | 17367258 yes
naloxone Analgesics oprm_human primary Class A (Rhodopsin) Opioid receptors approved 4 - 1971 small molecule antagonist 12566163 | 12799988 | 12842269 | 12887410 | 12909198 | 11752352 | 18354714 | 17918759 | 17367258 yes
naloxone Analgesics; overdose/drug toxicity oprm_human primary Class A (Rhodopsin) Opioid receptors approved 4 - 1971 small molecule antagonist 12566163 | 12799988 | 12842269 | 12887410 | 12909198 | 11752352 | 18354714 | 17918759 | 17367258 yes
naloxone Analgesics oprm_human primary Class A (Rhodopsin) Opioid receptors approved 4 - 2006 small molecule antagonist 12566163 | 12799988 | 12842269 | 12887410 | 12909198 | 11752352 | 18354714 | 17918759 | 17367258 yes
naltrexone Analgesics; for type 1A Charcot-Marie-Tooth disease oprd_human primary Class A (Rhodopsin) Opioid receptors approved 4 - 1998 small molecule antagonist 11752352 | 15788780 | 17661275 | 17487229 | 9673788 | 9040115 yes
naltrexone Analgesics oprd_human primary Class A (Rhodopsin) Opioid receptors approved 4 - 1998 small molecule antagonist 11752352 | 15788780 | 17661275 | 17487229 | 9673788 | 9040115 yes
naloxone Analgesics oprk_human primary Class A (Rhodopsin) Opioid receptors approved 4 - 1971 small molecule antagonist 17305578 | 17367258 | 18354714 yes
naloxone Analgesics oprd_human primary Class A (Rhodopsin) Opioid receptors approved 4 - 1971 small molecule antagonist 12650833 | 12657847 | 12749773 | 14646257 | 14708857 | 18354714 | 17367258 yes
naloxone Analgesics; overdose/drug toxicity oprd_human primary Class A (Rhodopsin) Opioid receptors approved 4 - 1971 small molecule antagonist 12650833 | 12657847 | 12749773 | 14646257 | 14708857 | 18354714 | 17367258 yes
naloxone Analgesics oprd_human primary Class A (Rhodopsin) Opioid receptors approved 4 - 2006 small molecule antagonist 12650833 | 12657847 | 12749773 | 14646257 | 14708857 | 18354714 | 17367258 yes
naloxone Analgesics; opioid addiction oprd_human primary Class A (Rhodopsin) Opioid receptors approved 4 - 1971 small molecule antagonist 12650833 | 12657847 | 12749773 | 14646257 | 14708857 | 18354714 | 17367258 yes
naloxone Analgesics; opioid addiction oprk_human primary Class A (Rhodopsin) Opioid receptors approved 4 - 1971 small molecule antagonist 17305578 | 17367258 | 18354714 yes
naloxone Analgesics; overdose/drug toxicity oprk_human primary Class A (Rhodopsin) Opioid receptors approved 4 - 1971 small molecule antagonist 17305578 | 17367258 | 18354714 yes
naloxone Analgesics oprk_human primary Class A (Rhodopsin) Opioid receptors approved 4 - 2006 small molecule antagonist 17305578 | 17367258 | 18354714 yes
naltrexone Appetite suppressant oprd_human primary Class A (Rhodopsin) Opioid receptors approved 4 - 1998 small molecule antagonist 11752352 | 15788780 | 17661275 | 17487229 | 9673788 | 9040115 yes
naltrexone substance abuse oprd_human primary Class A (Rhodopsin) Opioid receptors approved 4 - 1998 small molecule antagonist 11752352 | 15788780 | 17661275 | 17487229 | 9673788 | 9040115 yes
naltrexone addiction oprd_human primary Class A (Rhodopsin) Opioid receptors approved 4 - 2016 small molecule antagonist 11752352 | 15788780 | 17661275 | 17487229 | 9673788 | 9040115 yes
naltrexone Analgesics oprk_human primary Class A (Rhodopsin) Opioid receptors approved 4 - 1998 small molecule antagonist 11752352 | 18354714 | 9040115 | 17661275 | 19484223 yes
naltrexone Appetite suppressant oprk_human primary Class A (Rhodopsin) Opioid receptors approved 4 - 1998 small molecule antagonist 11752352 | 18354714 | 9040115 | 17661275 | 19484223 yes
naltrexone substance abuse oprk_human primary Class A (Rhodopsin) Opioid receptors approved 4 - 1998 small molecule antagonist 11752352 | 18354714 | 9040115 | 17661275 | 19484223 yes
naltrexone addiction oprk_human primary Class A (Rhodopsin) Opioid receptors approved 4 - 2016 small molecule antagonist 11752352 | 18354714 |