CHEMBL303556


SMILES O=C1Cc2c(ccc3c2O[C@@H](CNCc2ccccc2)CC3)N1
InChIKey NPATVCXCHCPFCB-OAHLLOKOSA-N

Chemical properties

Hydrogen bond acceptors 3
Hydrogen bond donors 2
Rotatable bonds 4
Molecular weight (Da) 308.2

Drug properties

Molecular type Small molecule
Endogenous/Surrogate Surrogate
Approved drug No

Database connections

Bioactivities

Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
D4 DRD4 Human Dopamine A pKi 6.45 6.45 6.45 ChEMBL
D2 DRD2 Rat Dopamine A pKi 8.23 9.04 9.85 ChEMBL
5-HT1A 5HT1A Rat 5-Hydroxytryptamine A pKi 8.07 8.07 8.07 ChEMBL
D3 DRD3 Human Dopamine A pKi 8.62 8.62 8.62 ChEMBL
D2 DRD2 Human Dopamine A pKi 8.03 8.03 8.03 ChEMBL
Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database