CHEMBL323562


SMILES CC1CCN(CCCOc2ccc(-c3ccc(C#N)cc3)cc2)CC1
InChIKey GMFZCHLJVCOHAA-UHFFFAOYSA-N

Chemical properties

Hydrogen bond acceptors 3
Hydrogen bond donors 0
Rotatable bonds 6
Molecular weight (Da) 334.2

Drug properties

Molecular type Small molecule
Endogenous/Surrogate Surrogate
Approved drug No

Database connections

Bioactivities

Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
H3 HRH3 Rat Histamine A pKi 8.01 8.01 8.01 ChEMBL
H2 HRH2 Human Histamine A pKi 5.04 5.04 5.04 ChEMBL
H1 HRH1 Human Histamine A pKi 6.37 6.37 6.37 ChEMBL
H3 HRH3 Human Histamine A pKi 7.86 7.86 7.86 ChEMBL
Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database