CHEMBL328681


SMILES COc1cccc2c1CCCC2NCCN1CCN(c2ccc(Cl)cc2)CC1
InChIKey CIXHJOHVILFKGB-UHFFFAOYSA-N

Chemical properties

Hydrogen bond acceptors 4
Hydrogen bond donors 1
Rotatable bonds 6
Molecular weight (Da) 399.2

Drug properties

Molecular type Small molecule
Endogenous/Surrogate Surrogate
Approved drug No

Database connections

Bioactivities

Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
D4 DRD4 Human Dopamine A pKi 7.5 7.5 7.5 ChEMBL
5-HT1A 5HT1A Rat 5-Hydroxytryptamine A pKi 6.09 6.09 6.09 ChEMBL
D2 DRD2 Human Dopamine A pKi 5.5 5.5 5.5 ChEMBL
Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database