CHEMBL3335537


SMILES c1ccc(CC[C@@H]2CN(Cc3nc4ccccc4[nH]3)CCO2)cc1
InChIKey JVQBISWUXRKBAJ-QGZVFWFLSA-N

Chemical properties

Hydrogen bond acceptors 3
Hydrogen bond donors 1
Rotatable bonds 5
Molecular weight (Da) 321.2

Drug properties

Molecular type Small molecule
Endogenous/Surrogate Surrogate
Approved drug No

Database connections

Bioactivities

Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
D4 DRD4 Human Dopamine A pKi 7.16 7.16 7.16 ChEMBL
D3 DRD3 Human Dopamine A pKi 4.8 4.8 4.8 ChEMBL
Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
D4 DRD4 Human Dopamine A pIC50 6.75 6.75 6.75 ChEMBL
D3 DRD3 Human Dopamine A pIC50 4.33 4.33 4.33 ChEMBL