CHEMBL3335539


SMILES COc1ccc(CN2CCOC(CCc3ccccc3)C2)cc1
InChIKey DFDOLOVKMMATDA-UHFFFAOYSA-N

Chemical properties

Hydrogen bond acceptors 3
Hydrogen bond donors 0
Rotatable bonds 6
Molecular weight (Da) 311.2

Drug properties

Molecular type Small molecule
Endogenous/Surrogate Surrogate
Approved drug No

Database connections

Bioactivities

Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
D4 DRD4 Human Dopamine A pKi 7.34 7.34 7.34 ChEMBL
D3 DRD3 Human Dopamine A pKi 5.56 5.56 5.56 ChEMBL
Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
D4 DRD4 Human Dopamine A pIC50 6.77 6.77 6.77 ChEMBL
D3 DRD3 Human Dopamine A pIC50 5.09 5.09 5.09 ChEMBL
D2 DRD2 Human Dopamine A pIC50 4.78 4.78 4.78 ChEMBL