CHEMBL3335554


SMILES FC(F)(F)Oc1ccc(CN2CCO[C@H](CCc3ccccc3)C2)cc1
InChIKey RXEIDFSWABFHSZ-LJQANCHMSA-N

Chemical properties

Hydrogen bond acceptors 3
Hydrogen bond donors 0
Rotatable bonds 6
Molecular weight (Da) 365.2

Drug properties

Molecular type Small molecule
Endogenous/Surrogate Surrogate
Approved drug No

Database connections

Bioactivities

Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
D4 DRD4 Human Dopamine A pKi 7.19 7.19 7.19 ChEMBL
D3 DRD3 Human Dopamine A pKi 5.56 5.56 5.56 ChEMBL
D2 DRD2 Human Dopamine A pKi 5.26 5.26 5.26 ChEMBL
Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
D4 DRD4 Human Dopamine A pIC50 6.64 6.64 6.64 ChEMBL
D3 DRD3 Human Dopamine A pIC50 5.09 5.09 5.09 ChEMBL