CHEMBL1180609


SMILES Oc1ccc2c(c1)O[C@@H](CN1CCc3ccccc3C1)CC2
InChIKey IWUPLAFLTUWLMF-GOSISDBHSA-N

Chemical properties

Hydrogen bond acceptors 3
Hydrogen bond donors 1
Rotatable bonds 2
Molecular weight (Da) 295.2

Drug properties

Molecular type Small molecule
Endogenous/Surrogate Surrogate
Approved drug No

Database connections

Bioactivities

Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
D4 DRD4 Human Dopamine A pKi 6.28 6.28 6.28 ChEMBL
D2 DRD2 Rat Dopamine A pKi 8.42 8.82 9.22 ChEMBL
D3 DRD3 Human Dopamine A pKi 9.7 9.7 9.7 ChEMBL
D2 DRD2 Human Dopamine A pKi 8.6 8.6 8.6 ChEMBL
5-HT1A 5HT1A Rat 5-Hydroxytryptamine A pKi 7.47 7.47 7.47 ChEMBL
Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database