CP-316,311
| SMILES | CCC(Oc1cc(C)nc(c1C)Oc1c(C)cc(cc1C)C)CC |
| InChIKey | ZSEJGVQTBLJRCQ-UHFFFAOYSA-N |
Chemical properties
| Hydrogen bond acceptors | 3 |
| Hydrogen bond donors | 0 |
| Rotatable bonds | 6 |
| Molecular weight (Da) | 327.2 |
Drug properties
| Molecular type | Small molecule |
| Endogenous/Surrogate | Surrogate |
| Approved drug | No |
Database connections
Bioactivities
| Receptor | Activity | Source | |||||||
|---|---|---|---|---|---|---|---|---|---|
| GTP | Uniprot | Species | Family | Class | Type | Min | Avg | Max | Database |
| CRF1 | CRFR1 | Human | Corticotropin-releasing factor | B1 | pKi | 8.07 | 8.07 | 8.07 | Guide to Pharmacology |
| CRF1 | CRFR1 | Human | Corticotropin-releasing factor | B1 | pKi | 8.07 | 8.07 | 8.07 | ChEMBL |
| CRF1 | CRFR1 | Rat | Corticotropin-releasing factor | B1 | pKi | 8.12 | 8.12 | 8.12 | ChEMBL |
| Receptor | Activity | Source | |||||||
|---|---|---|---|---|---|---|---|---|---|
| GTP | Uniprot | Species | Family | Class | Type | Min | Avg | Max | Database |
| CRF1 | CRFR1 | Rat | Corticotropin-releasing factor | B1 | pIC50 | 8.17 | 8.17 | 8.17 | Guide to Pharmacology |
| CRF1 | CRFR1 | Human | Corticotropin-releasing factor | B1 | pIC50 | 7.04 | 7.61 | 8.17 | ChEMBL |
| CRF1 | CRFR1 | Rat | Corticotropin-releasing factor | B1 | pIC50 | 8.17 | 8.17 | 8.17 | ChEMBL |