CHEMBL3361416


SMILES N=C(N)NCC(=O)NCC1(Nc2ccccc2)CCN(Cc2ccccc2)CC1
InChIKey JOTDNJDIGBWICX-UHFFFAOYSA-N

Chemical properties

Hydrogen bond acceptors 4
Hydrogen bond donors 5
Rotatable bonds 8
Molecular weight (Da) 394.2

Drug properties

Molecular type Small molecule
Endogenous/Surrogate Surrogate
Approved drug No

Database connections

Bioactivities

Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
NPFF1 NPFF1 Human Neuropeptide FF/neuropeptide AF A pKi 6.5 6.5 6.5 ChEMBL
NPFF2 NPFF2 Human Neuropeptide FF/neuropeptide AF A pKi 6.39 6.39 6.39 ChEMBL
κ OPRK Human Opioid A pKi 5.91 5.91 5.91 ChEMBL
Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
NPFF1 NPFF1 Human Neuropeptide FF/neuropeptide AF A pEC50 4.66 4.66 4.66 ChEMBL