CHEMBL1185415


SMILES c1ccc(N2CCN(CCCNC3=Nc4ccccc4OC3)CC2)cc1
InChIKey YYAHKCMGTOAAMI-UHFFFAOYSA-N

Chemical properties

Hydrogen bond acceptors 5
Hydrogen bond donors 1
Rotatable bonds 5
Molecular weight (Da) 350.2

Drug properties

Molecular type Small molecule
Endogenous/Surrogate Surrogate
Approved drug No

Database connections

Bioactivities

Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
D4 DRD4 Human Dopamine A pKi 7.75 7.75 7.75 ChEMBL
D3 DRD3 Human Dopamine A pKi 5.46 5.46 5.46 ChEMBL
D2 DRD2 Human Dopamine A pKi 5.7 5.7 5.7 ChEMBL
Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
D4 DRD4 Human Dopamine A pIC50 7.02 7.02 7.02 ChEMBL