CHEMBL11879


SMILES c1ccc(C(CCc2nc(CCN3CCCC3)c[nH]2)c2ccccc2)cc1
InChIKey HKZSTMPUPMSPLU-UHFFFAOYSA-N

Chemical properties

Hydrogen bond acceptors 2
Hydrogen bond donors 1
Rotatable bonds 8
Molecular weight (Da) 359.2

Drug properties

Molecular type Small molecule
Endogenous/Surrogate Surrogate
Approved drug No

Database connections

Bioactivities

Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
H1 HRH1 Guinea pig Histamine A pKd 9.02 9.02 9.02 ChEMBL
Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
H1 HRH1 Rat Histamine A pEC50 5.87 5.87 5.87 ChEMBL
H1 HRH1 Guinea pig Histamine A pEC50 6.53 6.53 6.53 ChEMBL