CHEMBL3663395


SMILES COc1ccc2cccnc2c1C(=O)N1C2CCC1C(COc1ccccn1)C2
InChIKey GAQMSECBJOFMLH-UHFFFAOYSA-N

Chemical properties

Hydrogen bond acceptors 5
Hydrogen bond donors 0
Rotatable bonds 5
Molecular weight (Da) 389.2

Drug properties

Molecular type Small molecule
Endogenous/Surrogate Surrogate
Approved drug No

Database connections

Bioactivities

Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
OX1 OX1R Rat Orexin A pKi 7.33 7.33 7.33 ChEMBL
OX1 OX1R Human Orexin A pKi 7.31 7.31 7.31 ChEMBL
OX2 OX2R Human Orexin A pKi 6.16 6.16 6.16 ChEMBL
Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database