CHEMBL3663462


SMILES O=C(c1c(O)ccc2cccnc12)N1C2CCC1C(COc1ccccn1)C2
InChIKey PSWFZILNDVZSTQ-UHFFFAOYSA-N

Chemical properties

Hydrogen bond acceptors 5
Hydrogen bond donors 1
Rotatable bonds 4
Molecular weight (Da) 375.2

Drug properties

Molecular type Small molecule
Endogenous/Surrogate Surrogate
Approved drug No

Database connections

Bioactivities

Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
OX1 OX1R Rat Orexin A pKi 6.58 6.58 6.58 ChEMBL
OX2 OX2R Human Orexin A pKi 6.11 6.11 6.11 ChEMBL
Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database