CHEMBL3665722


SMILES Cc1ccc2c(n1)CC[C@@H]2NC(=O)COc1cc(C(F)F)c2c(-c3cc(C)oc3C)nn(C)c2n1
InChIKey HGSOFDAPWKEOJR-IBGZPJMESA-N

Chemical properties

Hydrogen bond acceptors 7
Hydrogen bond donors 1
Rotatable bonds 6
Molecular weight (Da) 481.2

Drug properties

Molecular type Small molecule
Endogenous/Surrogate Surrogate
Approved drug No

Database connections

Bioactivities

Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
OX2 OX2R Human Orexin A pKd 6.57 6.57 6.57 ChEMBL
OX1 OX1R Human Orexin A pKd 6.91 6.91 6.91 ChEMBL
Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database