CHEMBL3669479


SMILES O=C1N(Cc2cccc(-c3ncccn3)c2)CCCC12CCN(c1cnc3ccccc3n1)CC2
InChIKey CWVRYJFYEUMVAB-UHFFFAOYSA-N

Chemical properties

Hydrogen bond acceptors 6
Hydrogen bond donors 0
Rotatable bonds 4
Molecular weight (Da) 464.2

Drug properties

Molecular type Small molecule
Endogenous/Surrogate Surrogate
Approved drug No

Database connections

Bioactivities

Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
OX1 OX1R Human Orexin A pKd 5.69 5.69 5.69 ChEMBL
OX1 OX1R Human Orexin A pKi 6.43 6.43 6.43 ChEMBL
OX2 OX2R Human Orexin A pKd 6.4 6.4 6.4 ChEMBL
OX2 OX2R Human Orexin A pKi 7.21 7.21 7.21 ChEMBL
Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database