CHEMBL3669490


SMILES Cc1nc(CN2CCCC3(CCN(c4cnc5ccccc5n4)CC3)C2=O)c(-c2cccc(F)c2)s1
InChIKey DPSCLWDDYMNDKJ-UHFFFAOYSA-N

Chemical properties

Hydrogen bond acceptors 6
Hydrogen bond donors 0
Rotatable bonds 4
Molecular weight (Da) 501.2

Drug properties

Molecular type Small molecule
Endogenous/Surrogate Surrogate
Approved drug No

Database connections

Bioactivities

Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
OX1 OX1R Human Orexin A pKd 5.94 5.94 5.94 ChEMBL
OX1 OX1R Human Orexin A pKi 6.36 6.36 6.36 ChEMBL
OX2 OX2R Human Orexin A pKd 6.66 6.66 6.66 ChEMBL
OX2 OX2R Human Orexin A pKi 7.26 7.26 7.26 ChEMBL
Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database