CHEMBL3669568


SMILES Cc1cc(N2CCC3(CCCN(Cc4c[nH]c5ccccc45)C3=O)CC2)nc2ccccc12
InChIKey DDYKRFYMWLKLMC-UHFFFAOYSA-N

Chemical properties

Hydrogen bond acceptors 3
Hydrogen bond donors 1
Rotatable bonds 3
Molecular weight (Da) 438.2

Drug properties

Molecular type Small molecule
Endogenous/Surrogate Surrogate
Approved drug No

Database connections

Bioactivities

Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
OX1 OX1R Human Orexin A pKd 7.05 7.05 7.05 ChEMBL
OX1 OX1R Human Orexin A pKi 6.94 6.94 6.94 ChEMBL
OX2 OX2R Human Orexin A pKi 7.85 7.85 7.85 ChEMBL
OX2 OX2R Human Orexin A pKd 7.92 7.92 7.92 ChEMBL
Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database