CHEMBL397770


SMILES OC1(c2cccc(Cl)c2Cl)CCN(Cc2c[nH]c3ccccc23)CC1
InChIKey ASKCQUQTSBOXCM-UHFFFAOYSA-N

Chemical properties

Hydrogen bond acceptors 2
Hydrogen bond donors 2
Rotatable bonds 3
Molecular weight (Da) 374.1

Drug properties

Molecular type Small molecule
Endogenous/Surrogate Surrogate
Approved drug No

Database connections

Bioactivities

Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
D4 DRD4 Human Dopamine A pKi 5.81 5.81 5.81 ChEMBL
D3 DRD3 Human Dopamine A pKi 6.56 6.56 6.56 ChEMBL
D2 DRD2 Human Dopamine A pKi 7.58 7.58 7.58 ChEMBL
Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
D3 DRD3 Human Dopamine A pEC50 6.63 6.63 6.63 ChEMBL
D2 DRD2 Human Dopamine A pEC50 7.46 7.46 7.46 ChEMBL