CHEMBL4087217


SMILES CCCN1CCN(c2ccc(O)c3c2OCC(=O)N3)CC1
InChIKey JNRGVRLFICIPND-UHFFFAOYSA-N

Chemical properties

Hydrogen bond acceptors 5
Hydrogen bond donors 2
Rotatable bonds 3
Molecular weight (Da) 291.2

Drug properties

Molecular type Small molecule
Endogenous/Surrogate Surrogate
Approved drug No

Database connections

Bioactivities

Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
D4 DRD4 Human Dopamine A pKi 6.06 6.06 6.06 ChEMBL
D3 DRD3 Human Dopamine A pKi 8.23 8.23 8.23 ChEMBL
D2 DRD2 Human Dopamine A pKi 6.92 7.19 7.46 ChEMBL
Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
D2 DRD2 Human Dopamine A pEC50 6.01 6.45 6.89 ChEMBL