CHEMBL423659


SMILES N#Cc1ccccc1N1CCN(CNC(=O)c2ccccc2)CC1
InChIKey YVWOLSSJSAUBFF-UHFFFAOYSA-N

Chemical properties

Hydrogen bond acceptors 4
Hydrogen bond donors 1
Rotatable bonds 4
Molecular weight (Da) 320.2

Drug properties

Molecular type Small molecule
Endogenous/Surrogate Surrogate
Approved drug No

Database connections

Bioactivities

Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
D4 DRD4 Human Dopamine A pKi 7.57 7.59 7.62 ChEMBL
D2 DRD2 Human Dopamine A pKi 5.38 5.45 5.52 ChEMBL
Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
D4 DRD4 Human Dopamine A pEC50 7.62 7.62 7.62 ChEMBL