CHEMBL4441358


SMILES CCc1cccc(N2CCNCC2)c1Cl
InChIKey CKRMQSOTIYEXQI-UHFFFAOYSA-N

Chemical properties

Hydrogen bond acceptors 2
Hydrogen bond donors 1
Rotatable bonds 2
Molecular weight (Da) 224.1

Drug properties

Molecular type Small molecule
Endogenous/Surrogate Surrogate
Approved drug No

Database connections

Bioactivities

Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
D4 DRD4 Human Dopamine A pKi 6.5 6.5 6.5 ChEMBL
5-HT2C 5HT2C Human 5-Hydroxytryptamine A pKi 8.27 8.27 8.27 ChEMBL
5-HT1A 5HT1A Human 5-Hydroxytryptamine A pKi 7.15 7.15 7.15 ChEMBL
5-HT2A 5HT2A Human 5-Hydroxytryptamine A pKi 8.15 8.15 8.15 ChEMBL
D3 DRD3 Human Dopamine A pKi 7.51 7.51 7.51 ChEMBL
D2 DRD2 Human Dopamine A pKi 6.86 6.86 6.86 ChEMBL
Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
5-HT1A 5HT1A Human 5-Hydroxytryptamine A pEC50 7.11 7.11 7.11 ChEMBL
D3 DRD3 Human Dopamine A pEC50 7.75 7.75 7.75 ChEMBL