CHEMBL446892


SMILES OC1(c2cccc(C(F)(F)F)c2)CCN(Cc2ccn(-c3ccccc3)c2)CC1
InChIKey TVQJPTVBALUGFW-UHFFFAOYSA-N

Chemical properties

Hydrogen bond acceptors 3
Hydrogen bond donors 1
Rotatable bonds 4
Molecular weight (Da) 400.2

Drug properties

Molecular type Small molecule
Endogenous/Surrogate Surrogate
Approved drug No

Database connections

Bioactivities

Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
D3 DRD3 Green monkey Dopamine A pKi 6.38 6.38 6.38 ChEMBL
D2 DRD2 Green monkey Dopamine A pKi 6.62 6.62 6.62 ChEMBL
D4 DRD4 Human Dopamine A pKi 6.31 6.31 6.31 ChEMBL
Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database