CHEMBL450021


SMILES COc1ccc(-c2nc(O)n(C3CCN(Cc4ccccc4)CC3)c2C)cc1
InChIKey JSOOBIHCFROWDG-UHFFFAOYSA-N

Chemical properties

Hydrogen bond acceptors 5
Hydrogen bond donors 1
Rotatable bonds 5
Molecular weight (Da) 377.2

Drug properties

Molecular type Small molecule
Endogenous/Surrogate Surrogate
Approved drug No

Database connections

Bioactivities

Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
D4 DRD4 Human Dopamine A pKi 7.92 7.92 7.92 ChEMBL
D3 DRD3 Human Dopamine A pKi 6.44 6.44 6.44 ChEMBL
D2 DRD2 Human Dopamine A pKi 6.96 6.96 6.96 ChEMBL
Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database