CHEMBL45187
| SMILES | CCC(CC)Nc1cc(C)nc2c(-c3ccc(OC)cc3C)c(C)nn12 |
| InChIKey | QBBJSFUFEUXTNU-UHFFFAOYSA-N |
Chemical properties
| Hydrogen bond acceptors | 5 |
| Hydrogen bond donors | 1 |
| Rotatable bonds | 6 |
| Molecular weight (Da) | 352.2 |
Drug properties
| Molecular type | Small molecule |
| Endogenous/Surrogate | Surrogate |
| Approved drug | No |
Database connections
Bioactivities
| Receptor | Activity | Source | |||||||
|---|---|---|---|---|---|---|---|---|---|
| GTP | Uniprot | Species | Family | Class | Type | Min | Avg | Max | Database |
| CRF1 | CRFR1 | Human | Corticotropin-releasing factor | B1 | pKi | 8.82 | 8.96 | 9.0 | ChEMBL |
| CRF1 | CRFR1 | Human | Corticotropin-releasing factor | B1 | pKd | 9.55 | 9.55 | 9.55 | ChEMBL |
| Receptor | Activity | Source | |||||||
|---|---|---|---|---|---|---|---|---|---|
| GTP | Uniprot | Species | Family | Class | Type | Min | Avg | Max | Database |
| CRF1 | CRFR1 | Human | Corticotropin-releasing factor | B1 | pIC50 | 8.0 | 8.0 | 8.0 | ChEMBL |