CHEMBL4591118


SMILES O=C(CN1CCN(c2ccc(Cl)cn2)CC1)Nc1cccnc1
InChIKey ITYRVEDPENLOKE-UHFFFAOYSA-N

Chemical properties

Hydrogen bond acceptors 5
Hydrogen bond donors 1
Rotatable bonds 4
Molecular weight (Da) 331.1

Drug properties

Molecular type Small molecule
Endogenous/Surrogate Surrogate
Approved drug No

Database connections

Bioactivities

Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
D4 DRD4 Human Dopamine A pKi 5.3 5.3 5.3 ChEMBL
Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
D4 DRD4 Human Dopamine A pIC50 4.4 4.52 4.63 ChEMBL
D2 DRD2 Human Dopamine A pIC50 4.06 4.06 4.06 ChEMBL