CHEMBL460854


SMILES OC1(c2ccc(Cl)cc2)CC2CCC(C1)N2CCc1c[nH]c2ccccc12
InChIKey NXGXYFWRVCUKFN-UHFFFAOYSA-N

Chemical properties

Hydrogen bond acceptors 2
Hydrogen bond donors 2
Rotatable bonds 4
Molecular weight (Da) 380.2

Drug properties

Molecular type Small molecule
Endogenous/Surrogate Surrogate
Approved drug No

Database connections

Bioactivities

Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
D4 DRD4 Human Dopamine A pKi 6.56 6.56 6.56 ChEMBL
D3 DRD3 Human Dopamine A pKi 7.75 7.75 7.75 ChEMBL
D2 DRD2 Human Dopamine A pKi 7.28 7.28 7.28 ChEMBL
D2 DRD2 Human Dopamine A pKi 7.28 7.28 7.28 PDSP Ki database
D3 DRD3 Human Dopamine A pKi 7.74 7.74 7.74 PDSP Ki database
D4 DRD4 Human Dopamine A pKi 6.56 6.56 6.56 PDSP Ki database
Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database