CHEMBL5222200


SMILES O=C1CCc2ccccc2N1CCCN1CCN(c2ccc(Cl)cc2)CC1
InChIKey WCAGCKMTLAATQU-UHFFFAOYSA-N

Chemical properties

Hydrogen bond acceptors 3
Hydrogen bond donors 0
Rotatable bonds 5
Molecular weight (Da) 383.2

Drug properties

Molecular type Small molecule
Endogenous/Surrogate Surrogate
Approved drug No

Database connections

Bioactivities

Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
D4 DRD4 Human Dopamine A pKi 8.83 9.0 9.18 ChEMBL
D3 DRD3 Human Dopamine A pKi 5.61 5.61 5.61 ChEMBL
D2 DRD2 Human Dopamine A pKi 5.26 5.26 5.26 ChEMBL
Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
D4 DRD4 Human Dopamine A pEC50 7.29 7.29 7.29 ChEMBL
D4 DRD4 Human Dopamine A pIC50 4.98 6.0 6.6 ChEMBL