CHEMBL5222201


SMILES O=C1CCc2ccccc2N1CCCN1CCN(c2ccccn2)CC1
InChIKey UWUBDOPGNONVDN-UHFFFAOYSA-N

Chemical properties

Hydrogen bond acceptors 4
Hydrogen bond donors 0
Rotatable bonds 5
Molecular weight (Da) 350.2

Drug properties

Molecular type Small molecule
Endogenous/Surrogate Surrogate
Approved drug No

Database connections

Bioactivities

Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
D4 DRD4 Human Dopamine A pKi 8.65 8.65 8.65 ChEMBL
D3 DRD3 Human Dopamine A pKi 5.59 5.59 5.59 ChEMBL
D2 DRD2 Human Dopamine A pKi 5.56 5.56 5.56 ChEMBL
Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
D4 DRD4 Human Dopamine A pEC50 7.91 7.99 8.07 ChEMBL
D4 DRD4 Human Dopamine A pIC50 7.17 7.17 7.17 ChEMBL