CHEMBL562620


SMILES COc1ccccc1N1CCN(Cc2cc3ccccn3n2)CC1
InChIKey PONADOYAURXJAH-UHFFFAOYSA-N

Chemical properties

Hydrogen bond acceptors 5
Hydrogen bond donors 0
Rotatable bonds 4
Molecular weight (Da) 322.2

Drug properties

Molecular type Small molecule
Endogenous/Surrogate Surrogate
Approved drug No

Database connections

Bioactivities

Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
D4 DRD4 Human Dopamine A pKi 8.64 8.78 8.92 ChEMBL
D3 DRD3 Human Dopamine A pKi 5.64 6.48 7.36 ChEMBL
D2 DRD2 Human Dopamine A pKi 5.44 6.15 6.55 ChEMBL
Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database