CHEMBL564089


SMILES COc1ncc(/C=C/C(=O)C23CC4CC(CC(C4)C2)C3)cc1C
InChIKey QVRVLZOOVQTCDX-ONEGZZNKSA-N

Chemical properties

Hydrogen bond acceptors 3
Hydrogen bond donors 0
Rotatable bonds 4
Molecular weight (Da) 311.2

Drug properties

Molecular type Small molecule
Endogenous/Surrogate Surrogate
Approved drug No

Database connections

Bioactivities

Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
mGlu1 GRM1 Rat Metabotropic glutamate C pKi 6.53 6.53 6.53 ChEMBL
mGlu5 GRM5 Rat Metabotropic glutamate C pKi 5.29 5.29 5.29 ChEMBL
Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database