CHEMBL62624


SMILES COc1ccc(Br)cc1-c1nc(CNC2CCN(Cc3ccccc3)CC2)cs1
InChIKey PGWQCIREQLHHHR-UHFFFAOYSA-N

Chemical properties

Hydrogen bond acceptors 5
Hydrogen bond donors 1
Rotatable bonds 7
Molecular weight (Da) 471.1

Drug properties

Molecular type Small molecule
Endogenous/Surrogate Surrogate
Approved drug No

Database connections

Bioactivities

Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
D1 DRD1 Bovine Dopamine A pKi 5.35 5.35 5.35 ChEMBL
D4 DRD4 Human Dopamine A pKi 6.4 6.4 6.4 ChEMBL
D3 DRD3 Human Dopamine A pKi 6.69 6.69 6.69 ChEMBL
D2 DRD2 Human Dopamine A pKi 6.71 6.85 6.98 ChEMBL
Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database