CHEMBL69571


SMILES O=C(NC/C=C/CN1CCN(c2cccc(Cl)c2Cl)CC1)c1cccc2c1-c1ccccc1C2
InChIKey LFQZHAKGDXWDRR-ONEGZZNKSA-N

Chemical properties

Hydrogen bond acceptors 3
Hydrogen bond donors 1
Rotatable bonds 6
Molecular weight (Da) 491.2

Drug properties

Molecular type Small molecule
Endogenous/Surrogate Surrogate
Approved drug No

Database connections

Bioactivities

Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
D3 DRD3 Rat Dopamine A pKi 7.72 7.72 7.72 ChEMBL
D4 DRD4 Human Dopamine A pKi 6.44 6.44 6.44 ChEMBL
D2 DRD2 Rat Dopamine A pKi 6.97 6.97 6.97 ChEMBL
D3 DRD3 Human Dopamine A pKi 7.19 7.64 8.09 ChEMBL
D2 DRD2 Human Dopamine A pKi 7.2 7.2 7.2 ChEMBL
Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
D3 DRD3 Human Dopamine A pIC50 6.94 6.94 6.94 ChEMBL