CHEMBL86504


SMILES FC(F)(F)c1nc2c(OCCNCc3ccccc3)cc(Cl)cc2[nH]1
InChIKey MMZIPJNBJQJCBM-UHFFFAOYSA-N

Chemical properties

Hydrogen bond acceptors 3
Hydrogen bond donors 2
Rotatable bonds 6
Molecular weight (Da) 369.1

Drug properties

Molecular type Small molecule
Endogenous/Surrogate Surrogate
Approved drug No

Database connections

Bioactivities

Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
D4 DRD4 Human Dopamine A pKi 8.15 8.15 8.15 ChEMBL
D2 DRD2 Rat Dopamine A pKi 7.94 8.54 9.15 ChEMBL
D3 DRD3 Human Dopamine A pKi 7.38 7.38 7.38 ChEMBL
D2 DRD2 Human Dopamine A pKi 7.49 7.49 7.49 ChEMBL
Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database