BIIE0246


SMILES C1CCC(C1)(CC(=O)NC(CCCN=C(N)N)C(=O)NCCN2C(=O)N(N(C2=O)C3=CC=CC=C3)C4=CC=CC=C4)CC(=O)N5CCN(CC5)C6C7=CC=CC=C7C(=O)NC8=CC=CC=C68
InChIKey RSJAXPUYVJKAAA-UHFFFAOYSA-N

Chemical properties

Hydrogen bond acceptors 11
Hydrogen bond donors 5
Rotatable bonds 16
Molecular weight (Da) 895.4

Drug properties

Molecular type Small molecule
Endogenous/Surrogate Surrogate
Approved drug No

Database connections

Bioactivities

Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
Y2 Q9ERC0 Rat Neuropeptide Y A pKi 8.05 8.12 8.19 PDSP Ki database
Y5 NPY5R Rat Neuropeptide Y A pKi 6.0 6.0 6.0 PDSP Ki database
Y2 NPY2R Chicken Neuropeptide Y A pKi 6.2 6.2 6.2 PDSP Ki database
Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database