(S)-1-(3-(3-(3,4-dimethoxyphenyl)-4,5-dihydroisoxazol-5-yl)propyl)-4-(2-ethoxyphenyl)piperazine


SMILES CCOC1=CC=CC=C1N2CCN(CC2)CCCC3CC(=NO3)C4=CC(=C(C=C4)OC)OC
InChIKey BUSRXNBLQQVZCO-UHFFFAOYSA-N

Chemical properties

Hydrogen bond acceptors 7
Hydrogen bond donors 0
Rotatable bonds 10
Molecular weight (Da) 453.3

Drug properties

Molecular type Small molecule
Endogenous/Surrogate Surrogate
Approved drug No

Database connections

Bioactivities

Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
D2 DRD2 Human Dopamine A pKi 7.15 7.25 7.34 PDSP Ki database
D3 DRD3 Human Dopamine A pKi 8.29 8.48 8.68 PDSP Ki database
D4 DRD4 Human Dopamine A pKi 6.29 6.47 6.65 PDSP Ki database
Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database