CHEMBL152587


SMILES COc1cccc(C(=O)NCCCCN2CCN(c3nccc4ccccc34)CC2)c1
InChIKey MGZOXAOAEVISHM-UHFFFAOYSA-N

Chemical properties

Hydrogen bond acceptors 5
Hydrogen bond donors 1
Rotatable bonds 8
Molecular weight (Da) 418.2

Drug properties

Molecular type Small molecule
Endogenous/Surrogate Surrogate
Approved drug No

Database connections

Bioactivities

Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
D3 DRD3 Rat Dopamine A pKi 8.02 8.02 8.02 ChEMBL
5-HT1A 5HT1A Rat 5-Hydroxytryptamine A pKi 7.9 7.9 7.9 ChEMBL
D2 DRD2 Human Dopamine A pKi 6.11 6.11 6.11 ChEMBL
D4 DRD4 Human Dopamine A pKi 6.78 6.78 6.78 ChEMBL
Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database