CHEMBL178447


SMILES O=C(c1ccc2ncccc2c1)N1CCC(N2CC[C@H](Cc3ccc(Cl)c(Cl)c3)[C@H](CO)C2)CC1
InChIKey BKSRLDUBSLBPQQ-OFNKIYASSA-N

Chemical properties

Hydrogen bond acceptors 4
Hydrogen bond donors 1
Rotatable bonds 5
Molecular weight (Da) 511.2

Drug properties

Molecular type Small molecule
Endogenous/Surrogate Surrogate
Approved drug No

Database connections

Bioactivities

Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
CCR3 CCR3 Rhesus macaque Chemokine A pKi 8.14 8.14 8.14 ChEMBL
CCR3 CCR3 Rat Chemokine A pKi 5.53 5.53 5.53 ChEMBL
CCR3 CCR3 Mouse Chemokine A pKi 6.22 6.22 6.22 ChEMBL
CCR3 CCR3 Human Chemokine A pKi 7.3 8.08 8.48 ChEMBL
Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database