CHEMBL1940410


SMILES Fc1ccc(SCCCN2CCN(c3ccc(C(F)(F)F)cc3)CC2)cc1
InChIKey QLMIVFXMQPUHKG-UHFFFAOYSA-N

Chemical properties

Hydrogen bond acceptors 3
Hydrogen bond donors 0
Rotatable bonds 6
Molecular weight (Da) 398.1

Drug properties

Molecular type Small molecule
Endogenous/Surrogate Surrogate
Approved drug No

Database connections

Bioactivities

Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
D4 DRD4 Rat Dopamine A pKi 7.05 7.05 7.05 ChEMBL
5-HT1A 5HT1A Human 5-Hydroxytryptamine A pKi 5.97 5.97 5.97 ChEMBL
5-HT2A 5HT2A Human 5-Hydroxytryptamine A pKi 5.95 5.95 5.95 ChEMBL
D3 DRD3 Human Dopamine A pKi 6.26 6.26 6.26 ChEMBL
D2 DRD2 Human Dopamine A pKi 5.32 5.32 5.32 ChEMBL
Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database