CHEMBL1946123


SMILES OC1(c2ccc(Cl)cc2)C[C@@H]2CC[C@H](C1)N2CCCCc1ccc(F)cc1
InChIKey SFPSQBFPUCFLEZ-AIZNXBIQSA-N

Chemical properties

Hydrogen bond acceptors 2
Hydrogen bond donors 1
Rotatable bonds 6
Molecular weight (Da) 387.2

Drug properties

Molecular type Small molecule
Endogenous/Surrogate Surrogate
Approved drug No

Database connections

Bioactivities

Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
D4 DRD4 Rat Dopamine A pKi 8.03 8.03 8.03 ChEMBL
H1 HRH1 Human Histamine A pKi 5.76 5.76 5.76 ChEMBL
5-HT2C 5HT2C Human 5-Hydroxytryptamine A pKi 5.61 5.61 5.61 ChEMBL
5-HT1A 5HT1A Human 5-Hydroxytryptamine A pKi 6.99 6.99 6.99 ChEMBL
5-HT2A 5HT2A Human 5-Hydroxytryptamine A pKi 6.5 6.5 6.5 ChEMBL
D3 DRD3 Human Dopamine A pKi 8.01 8.01 8.01 ChEMBL
D2 DRD2 Human Dopamine A pKi 7.48 7.48 7.48 ChEMBL
Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database