CHEMBL2112461


SMILES C[C@@]1(O)CCN(CCCOc2ccc(-c3ccc(C#N)cc3)cc2)C1
InChIKey VOSJYQCPCAXSLK-OAQYLSRUSA-N

Chemical properties

Hydrogen bond acceptors 4
Hydrogen bond donors 1
Rotatable bonds 6
Molecular weight (Da) 336.2

Drug properties

Molecular type Small molecule
Endogenous/Surrogate Surrogate
Approved drug No

Database connections

Bioactivities

Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
H3 HRH3 Rat Histamine A pKi 7.81 7.81 7.81 ChEMBL
H2 HRH2 Human Histamine A pKi 4.82 4.82 4.82 ChEMBL
H1 HRH1 Human Histamine A pKi 5.41 5.41 5.41 ChEMBL
H3 HRH3 Human Histamine A pKi 8.39 8.39 8.39 ChEMBL
Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database