CHEMBL238263


SMILES O=c1c2sc3ncc4cn[nH]c4c3c2ncn1-c1ccc(Cl)cc1
InChIKey LKBNBRKQCADHSO-UHFFFAOYSA-N

Chemical properties

Hydrogen bond acceptors 6
Hydrogen bond donors 1
Rotatable bonds 1
Molecular weight (Da) 353.0

Drug properties

Molecular type Small molecule
Endogenous/Surrogate Surrogate
Approved drug No

Database connections

Bioactivities

Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
mGlu1 GRM1 Rat Metabotropic glutamate C pKi 7.71 7.71 7.71 ChEMBL
Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
mGlu1 GRM1 Human Metabotropic glutamate C pIC50 7.42 7.42 7.42 ChEMBL