CHEMBL2387265


SMILES O=c1cc(-c2ccccc2)c2ccc(OCCCCN3CCC(c4noc5cc(F)ccc45)CC3)cc2o1
InChIKey GKSPYGYNVWVOQQ-UHFFFAOYSA-N

Chemical properties

Hydrogen bond acceptors 6
Hydrogen bond donors 0
Rotatable bonds 8
Molecular weight (Da) 512.2

Drug properties

Molecular type Small molecule
Endogenous/Surrogate Surrogate
Approved drug No

Database connections

Bioactivities

Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
D3 DRD3 Rat Dopamine A pKi 7.14 7.14 7.14 ChEMBL
5-HT2C 5HT2C Rat 5-Hydroxytryptamine A pKi 6.59 6.59 6.59 ChEMBL
H1 HRH1 Guinea pig Histamine A pKi 7.42 7.42 7.42 ChEMBL
D2 DRD2 Rat Dopamine A pKi 7.83 7.83 7.83 ChEMBL
5-HT1A 5HT1A Rat 5-Hydroxytryptamine A pKi 7.9 7.9 7.9 ChEMBL
Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database