CHEMBL2413514


SMILES Cc1noc(-c2ccccc2CN2CCCC3(CCN(c4cnc5ccccc5n4)CC3)C2=O)n1
InChIKey ORQIXYIDXFFJOU-UHFFFAOYSA-N

Chemical properties

Hydrogen bond acceptors 7
Hydrogen bond donors 0
Rotatable bonds 4
Molecular weight (Da) 468.2

Drug properties

Molecular type Small molecule
Endogenous/Surrogate Surrogate
Approved drug No

Database connections

Bioactivities

Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
OX1 OX1R Human Orexin A pKi 5.85 5.85 5.85 ChEMBL
OX1 OX1R Human Orexin A pKd 5.56 5.56 5.56 ChEMBL
OX2 OX2R Human Orexin A pKi 7.6 7.6 7.6 ChEMBL
OX2 OX2R Human Orexin A pKd 6.61 6.61 6.61 ChEMBL
Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database