CHEMBL246637


SMILES OC1(c2ccc(Cl)c(Cl)c2)CCN(Cc2c[nH]c3ccccc23)CC1
InChIKey YZIXUQBOLGXTJS-UHFFFAOYSA-N

Chemical properties

Hydrogen bond acceptors 2
Hydrogen bond donors 2
Rotatable bonds 3
Molecular weight (Da) 374.1

Drug properties

Molecular type Small molecule
Endogenous/Surrogate Surrogate
Approved drug No

Database connections

Bioactivities

Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
D4 DRD4 Human Dopamine A pKi 5.96 5.96 5.96 ChEMBL
D3 DRD3 Human Dopamine A pKi 6.96 6.96 6.96 ChEMBL
D2 DRD2 Human Dopamine A pKi 8.16 8.16 8.16 ChEMBL
Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
D3 DRD3 Human Dopamine A pEC50 7.38 7.38 7.38 ChEMBL
D2 DRD2 Human Dopamine A pEC50 7.82 7.82 7.82 ChEMBL