CHEMBL251835


SMILES CN1C[C@H](C(=O)N2CCN(c3ccc4nonc4c3)CC2)C[C@@H]2c3cccc4[nH]c(Br)c(c34)C[C@H]21
InChIKey GZFMZJDVLOZLLL-OMXJDXKCSA-N

Chemical properties

Hydrogen bond acceptors 6
Hydrogen bond donors 1
Rotatable bonds 2
Molecular weight (Da) 534.1

Drug properties

Molecular type Small molecule
Endogenous/Surrogate Surrogate
Approved drug No

Database connections

Bioactivities

Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
SST1 SSR1 Rat Somatostatin A pKd 9.43 9.43 9.43 ChEMBL
SST2 SSR2 Rat Somatostatin A pKd 5.19 5.19 5.19 ChEMBL
SST1 SSR1 Human Somatostatin A pKd 8.91 8.91 8.91 ChEMBL
SST4 SSR4 Human Somatostatin A pKd 5.44 5.44 5.44 ChEMBL
SST2 SSR2 Human Somatostatin A pKd 5.17 5.17 5.17 ChEMBL
SST5 SSR5 Human Somatostatin A pKd 5.19 5.19 5.19 ChEMBL
SST3 SSR3 Human Somatostatin A pKd 5.63 5.63 5.63 ChEMBL
D4 DRD4 Human Dopamine A pKd 7.11 7.11 7.11 ChEMBL
5-HT1A 5HT1A Human 5-Hydroxytryptamine A pKd 7.55 7.55 7.55 ChEMBL
D2 DRD2 Human Dopamine A pKd 6.9 6.9 6.9 ChEMBL
Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database